emodin has been researched along with Adverse Drug Event in 2 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
| Excerpt | Relevance | Reference |
|---|---|---|
| " multiflorum vary, and the toxic components are even more controversial." | 1.72 | Polygonum multiflorum Thunb. Induces hepatotoxicity in SD rats and hepatocyte spheroids by Disrupting the metabolism of bilirubin and bile acid. ( Ma, S; Wang, Q; Wen, H; Zhang, Y, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Q | 1 |
| Wen, H | 1 |
| Ma, S | 1 |
| Zhang, Y | 1 |
| Li, D | 1 |
| Song, Q | 1 |
| Ji, X | 1 |
| Lyu, Y | 1 |
| Lai, YS | 1 |
| Zuo, Z | 1 |
2 other studies available for emodin and Adverse Drug Event
| Article | Year |
|---|---|
Polygonum multiflorum Thunb. Induces hepatotoxicity in SD rats and hepatocyte spheroids by Disrupting the metabolism of bilirubin and bile acid.
Topics: Animals; Bile Acids and Salts; Bilirubin; Chemical and Drug Induced Liver Injury; Drug-Related Side | 2022 |
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside enhances the hepatotoxicity of emodin in vitro and in vivo.
Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liv | 2022 |