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emodin and Adenocarcinoma

emodin has been researched along with Adenocarcinoma in 13 studies

Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"This study investigated the mechanism of the cytotoxic effect of emodin, an active anthraquinone, on human lung adenocarcinoma A549 cells."7.80Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis. ( Chan, SW; Guo, DJ; Guo, ZD; Kwan, YW; Lee, SM; Leung, GP; Li, WY; Ng, YF; Yu, PH; Zhang, H, 2014)
"To investigate the anti-tumor mechanisms of emodin on human lung adenocarcinoma cell line Anip973 (LACC)."7.73[Inhibitory effect of emodin on proliferation of human lung adenocarcinoma cells in vitro]. ( Bao, Y; Li, JN; Lu, FZ; Xiao, JL, 2005)
"To study the suppressive role of emodin on the growth and its effect on the proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line Anip 973."7.73[Effects of emodin on proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line Anip 973]. ( Li, JN; Lv, FZ; Xiao, JL, 2006)
"Emodin is an anthraquinone derivative originally isolated from Chinese rhubarb, possesses anticancer properties."5.46Emodin Inhibits ATP-Induced Proliferation and Migration by Suppressing P2Y Receptors in Human Lung Adenocarcinoma Cells. ( Guan, R; Li, L; Shen, L; Song, N; Wang, X; Zhu, D, 2017)
"The emodin treatment induced P450s 1A1 and 1B1 mRNA in human lung carcinoma NCI-H322 and breast cancer MCF-7 cells."5.31Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5. ( Chen, TL; Ueng, TH; Wang, HW; Yang, PC, 2001)
"This study investigated the mechanism of the cytotoxic effect of emodin, an active anthraquinone, on human lung adenocarcinoma A549 cells."3.80Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis. ( Chan, SW; Guo, DJ; Guo, ZD; Kwan, YW; Lee, SM; Leung, GP; Li, WY; Ng, YF; Yu, PH; Zhang, H, 2014)
"To investigate the anti-tumor mechanisms of emodin on human lung adenocarcinoma cell line Anip973 (LACC)."3.73[Inhibitory effect of emodin on proliferation of human lung adenocarcinoma cells in vitro]. ( Bao, Y; Li, JN; Lu, FZ; Xiao, JL, 2005)
"To study the suppressive role of emodin on the growth and its effect on the proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line Anip 973."3.73[Effects of emodin on proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line Anip 973]. ( Li, JN; Lv, FZ; Xiao, JL, 2006)
"Emodin is an anthraquinone derivative originally isolated from Chinese rhubarb, possesses anticancer properties."1.46Emodin Inhibits ATP-Induced Proliferation and Migration by Suppressing P2Y Receptors in Human Lung Adenocarcinoma Cells. ( Guan, R; Li, L; Shen, L; Song, N; Wang, X; Zhu, D, 2017)
"Emodin is an active component of Chinese medicinal herbs and can inhibit the activation of Akt and NF-κB."1.37Antitumor and apoptosis-promoting properties of emodin, an anthraquinone derivative from Rheum officinale Baill, against pancreatic cancer in mice via inhibition of Akt activation. ( Chen, H; Fan, L; Guo, HC; Lin, SZ; Liu, A; Liu, DL; Liu, HB; Ni, ZL; Qiu, MX; Tong, HF; Wang, ZH; Wei, WT, 2011)
"The emodin treatment induced P450s 1A1 and 1B1 mRNA in human lung carcinoma NCI-H322 and breast cancer MCF-7 cells."1.31Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5. ( Chen, TL; Ueng, TH; Wang, HW; Yang, PC, 2001)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (46.15)29.6817
2010's5 (38.46)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Shi, X1
Huang, B1
Zhu, J1
Yamaguchi, T1
Hu, A1
Tabuchi, M1
Watanabe, D1
Yoshikawa, S1
Mizushima, S1
Mizushima, A1
Xia, S1
Li, Q1
Zhang, D1
Sui, X1
Song, T1
Hu, L1
Xu, X1
Wang, X2
Wang, F1
Braumann, C1
Koplin, G1
Geier, C1
Höhn, P1
Pohlenz, J1
Dubiel, W1
Rogalla, S1
Li, L1
Guan, R1
Zhu, D1
Song, N1
Shen, L1
Li, WY1
Ng, YF1
Zhang, H1
Guo, ZD1
Guo, DJ1
Kwan, YW1
Leung, GP1
Lee, SM1
Yu, PH1
Chan, SW1
Wei, WT1
Chen, H1
Ni, ZL1
Liu, HB1
Tong, HF1
Fan, L1
Liu, A1
Qiu, MX1
Liu, DL1
Guo, HC1
Wang, ZH1
Lin, SZ1
Ma, YS1
Weng, SW1
Lin, MW1
Lu, CC1
Chiang, JH1
Yang, JS1
Lai, KC1
Lin, JP1
Tang, NY1
Lin, JG1
Chung, JG1
Su, YT1
Chang, HL1
Shyue, SK1
Hsu, SL1
Li, JN2
Lu, FZ1
Xiao, JL2
Bao, Y1
Götz, C1
Bachmann, C1
Montenarh, M1
Lv, FZ1
Yu, CX1
Zhang, XQ1
Kang, LD1
Zhang, PJ1
Chen, WW1
Liu, WW1
Liu, QW1
Zhang, JY1
Wang, HW1
Chen, TL1
Yang, PC1
Ueng, TH1

Other Studies

13 other studies available for emodin and Adenocarcinoma

ArticleYear
A network pharmacology-based investigation of emodin against pancreatic adenocarcinoma.
    Medicine, 2023, May-19, Volume: 102, Issue:20

    Topics: Adenocarcinoma; Emodin; Gene Expression Regulation, Neoplastic; Humans; Molecular Docking Simulation

2023
The Warburg effect drives cachectic states in patients with pancreatobiliary adenocarcinoma.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023, Volume: 37, Issue:9

    Topics: Adenocarcinoma; Animals; Cachexia; Emodin; Mice; Mice, Nude; Pancreatic Neoplasms

2023
Dose-dependent role of novel agents emodin and BTB14431 in colonic cancer treatment in rats.
    Acta chirurgica Belgica, 2017, Volume: 117, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Blood Cell Count; Colonic Neoplasms; Dise

2017
Emodin Inhibits ATP-Induced Proliferation and Migration by Suppressing P2Y Receptors in Human Lung Adenocarcinoma Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 44, Issue:4

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Adenosine Triphosphate; bcl-2-Associated X Prote

2017
Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis.
    Inflammopharmacology, 2014, Volume: 22, Issue:2

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Checkpo

2014
Antitumor and apoptosis-promoting properties of emodin, an anthraquinone derivative from Rheum officinale Baill, against pancreatic cancer in mice via inhibition of Akt activation.
    International journal of oncology, 2011, Volume: 39, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Body Weight;

2011
Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Calcium; Caspase 3; Caspas

2012
Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway.
    Biochemical pharmacology, 2005, Jul-15, Volume: 70, Issue:2

    Topics: Adenocarcinoma; Animals; Apoptosis; Cell Line, Tumor; Emodin; Humans; Lung Neoplasms; Mitochondria;

2005
[Inhibitory effect of emodin on proliferation of human lung adenocarcinoma cells in vitro].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2005, Volume: 25, Issue:7

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation;

2005
Inhibition of protein kinase CK2 leads to a modulation of androgen receptor dependent transcription in prostate cancer cells.
    The Prostate, 2007, Feb-01, Volume: 67, Issue:2

    Topics: Adenocarcinoma; Benzimidazoles; Blotting, Western; Casein Kinase II; Cell Line, Tumor; Dose-Response

2007
[Effects of emodin on proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line Anip 973].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2006, Volume: 26, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase 3; Ce

2006
Emodin induces apoptosis in human prostate cancer cell LNCaP.
    Asian journal of andrology, 2008, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cell

2008
Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5.
    Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:9

    Topics: Adenocarcinoma; Anthracenes; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-45

2001