emodin has been researched along with Adenocarcinoma in 13 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the mechanism of the cytotoxic effect of emodin, an active anthraquinone, on human lung adenocarcinoma A549 cells." | 7.80 | Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis. ( Chan, SW; Guo, DJ; Guo, ZD; Kwan, YW; Lee, SM; Leung, GP; Li, WY; Ng, YF; Yu, PH; Zhang, H, 2014) |
| "To investigate the anti-tumor mechanisms of emodin on human lung adenocarcinoma cell line Anip973 (LACC)." | 7.73 | [Inhibitory effect of emodin on proliferation of human lung adenocarcinoma cells in vitro]. ( Bao, Y; Li, JN; Lu, FZ; Xiao, JL, 2005) |
| "To study the suppressive role of emodin on the growth and its effect on the proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line Anip 973." | 7.73 | [Effects of emodin on proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line Anip 973]. ( Li, JN; Lv, FZ; Xiao, JL, 2006) |
| "Emodin is an anthraquinone derivative originally isolated from Chinese rhubarb, possesses anticancer properties." | 5.46 | Emodin Inhibits ATP-Induced Proliferation and Migration by Suppressing P2Y Receptors in Human Lung Adenocarcinoma Cells. ( Guan, R; Li, L; Shen, L; Song, N; Wang, X; Zhu, D, 2017) |
| "The emodin treatment induced P450s 1A1 and 1B1 mRNA in human lung carcinoma NCI-H322 and breast cancer MCF-7 cells." | 5.31 | Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5. ( Chen, TL; Ueng, TH; Wang, HW; Yang, PC, 2001) |
| "This study investigated the mechanism of the cytotoxic effect of emodin, an active anthraquinone, on human lung adenocarcinoma A549 cells." | 3.80 | Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis. ( Chan, SW; Guo, DJ; Guo, ZD; Kwan, YW; Lee, SM; Leung, GP; Li, WY; Ng, YF; Yu, PH; Zhang, H, 2014) |
| "To investigate the anti-tumor mechanisms of emodin on human lung adenocarcinoma cell line Anip973 (LACC)." | 3.73 | [Inhibitory effect of emodin on proliferation of human lung adenocarcinoma cells in vitro]. ( Bao, Y; Li, JN; Lu, FZ; Xiao, JL, 2005) |
| "To study the suppressive role of emodin on the growth and its effect on the proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line Anip 973." | 3.73 | [Effects of emodin on proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line Anip 973]. ( Li, JN; Lv, FZ; Xiao, JL, 2006) |
| "Emodin is an anthraquinone derivative originally isolated from Chinese rhubarb, possesses anticancer properties." | 1.46 | Emodin Inhibits ATP-Induced Proliferation and Migration by Suppressing P2Y Receptors in Human Lung Adenocarcinoma Cells. ( Guan, R; Li, L; Shen, L; Song, N; Wang, X; Zhu, D, 2017) |
| "Emodin is an active component of Chinese medicinal herbs and can inhibit the activation of Akt and NF-κB." | 1.37 | Antitumor and apoptosis-promoting properties of emodin, an anthraquinone derivative from Rheum officinale Baill, against pancreatic cancer in mice via inhibition of Akt activation. ( Chen, H; Fan, L; Guo, HC; Lin, SZ; Liu, A; Liu, DL; Liu, HB; Ni, ZL; Qiu, MX; Tong, HF; Wang, ZH; Wei, WT, 2011) |
| "The emodin treatment induced P450s 1A1 and 1B1 mRNA in human lung carcinoma NCI-H322 and breast cancer MCF-7 cells." | 1.31 | Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5. ( Chen, TL; Ueng, TH; Wang, HW; Yang, PC, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, X | 1 |
| Huang, B | 1 |
| Zhu, J | 1 |
| Yamaguchi, T | 1 |
| Hu, A | 1 |
| Tabuchi, M | 1 |
| Watanabe, D | 1 |
| Yoshikawa, S | 1 |
| Mizushima, S | 1 |
| Mizushima, A | 1 |
| Xia, S | 1 |
| Li, Q | 1 |
| Zhang, D | 1 |
| Sui, X | 1 |
| Song, T | 1 |
| Hu, L | 1 |
| Xu, X | 1 |
| Wang, X | 2 |
| Wang, F | 1 |
| Braumann, C | 1 |
| Koplin, G | 1 |
| Geier, C | 1 |
| Höhn, P | 1 |
| Pohlenz, J | 1 |
| Dubiel, W | 1 |
| Rogalla, S | 1 |
| Li, L | 1 |
| Guan, R | 1 |
| Zhu, D | 1 |
| Song, N | 1 |
| Shen, L | 1 |
| Li, WY | 1 |
| Ng, YF | 1 |
| Zhang, H | 1 |
| Guo, ZD | 1 |
| Guo, DJ | 1 |
| Kwan, YW | 1 |
| Leung, GP | 1 |
| Lee, SM | 1 |
| Yu, PH | 1 |
| Chan, SW | 1 |
| Wei, WT | 1 |
| Chen, H | 1 |
| Ni, ZL | 1 |
| Liu, HB | 1 |
| Tong, HF | 1 |
| Fan, L | 1 |
| Liu, A | 1 |
| Qiu, MX | 1 |
| Liu, DL | 1 |
| Guo, HC | 1 |
| Wang, ZH | 1 |
| Lin, SZ | 1 |
| Ma, YS | 1 |
| Weng, SW | 1 |
| Lin, MW | 1 |
| Lu, CC | 1 |
| Chiang, JH | 1 |
| Yang, JS | 1 |
| Lai, KC | 1 |
| Lin, JP | 1 |
| Tang, NY | 1 |
| Lin, JG | 1 |
| Chung, JG | 1 |
| Su, YT | 1 |
| Chang, HL | 1 |
| Shyue, SK | 1 |
| Hsu, SL | 1 |
| Li, JN | 2 |
| Lu, FZ | 1 |
| Xiao, JL | 2 |
| Bao, Y | 1 |
| Götz, C | 1 |
| Bachmann, C | 1 |
| Montenarh, M | 1 |
| Lv, FZ | 1 |
| Yu, CX | 1 |
| Zhang, XQ | 1 |
| Kang, LD | 1 |
| Zhang, PJ | 1 |
| Chen, WW | 1 |
| Liu, WW | 1 |
| Liu, QW | 1 |
| Zhang, JY | 1 |
| Wang, HW | 1 |
| Chen, TL | 1 |
| Yang, PC | 1 |
| Ueng, TH | 1 |
13 other studies available for emodin and Adenocarcinoma
| Article | Year |
|---|---|
A network pharmacology-based investigation of emodin against pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Emodin; Gene Expression Regulation, Neoplastic; Humans; Molecular Docking Simulation | 2023 |
The Warburg effect drives cachectic states in patients with pancreatobiliary adenocarcinoma.
Topics: Adenocarcinoma; Animals; Cachexia; Emodin; Mice; Mice, Nude; Pancreatic Neoplasms | 2023 |
Dose-dependent role of novel agents emodin and BTB14431 in colonic cancer treatment in rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Blood Cell Count; Colonic Neoplasms; Dise | 2017 |
Emodin Inhibits ATP-Induced Proliferation and Migration by Suppressing P2Y Receptors in Human Lung Adenocarcinoma Cells.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Adenosine Triphosphate; bcl-2-Associated X Prote | 2017 |
Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Checkpo | 2014 |
Antitumor and apoptosis-promoting properties of emodin, an anthraquinone derivative from Rheum officinale Baill, against pancreatic cancer in mice via inhibition of Akt activation.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Body Weight; | 2011 |
Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Calcium; Caspase 3; Caspas | 2012 |
Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway.
Topics: Adenocarcinoma; Animals; Apoptosis; Cell Line, Tumor; Emodin; Humans; Lung Neoplasms; Mitochondria; | 2005 |
[Inhibitory effect of emodin on proliferation of human lung adenocarcinoma cells in vitro].
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; | 2005 |
Inhibition of protein kinase CK2 leads to a modulation of androgen receptor dependent transcription in prostate cancer cells.
Topics: Adenocarcinoma; Benzimidazoles; Blotting, Western; Casein Kinase II; Cell Line, Tumor; Dose-Response | 2007 |
[Effects of emodin on proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line Anip 973].
Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase 3; Ce | 2006 |
Emodin induces apoptosis in human prostate cancer cell LNCaP.
Topics: Adenocarcinoma; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cell | 2008 |
Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5.
Topics: Adenocarcinoma; Anthracenes; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-45 | 2001 |