emodin has been researched along with Adenocarcinoma of Lung in 5 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Adenocarcinoma of Lung: A carcinoma originating in the lung and the most common lung cancer type in never-smokers. Malignant cells exhibit distinct features such as glandular epithelial, or tubular morphology. Mutations in KRAS, EGFR, BRAF, and ERBB2 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the mechanism of the cytotoxic effect of emodin, an active anthraquinone, on human lung adenocarcinoma A549 cells." | 7.80 | Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis. ( Chan, SW; Guo, DJ; Guo, ZD; Kwan, YW; Lee, SM; Leung, GP; Li, WY; Ng, YF; Yu, PH; Zhang, H, 2014) |
| "Lung adenocarcinoma is the most common type of lung cancer." | 5.91 | The ethyl acetate extract of Wenxia Changfu Formula inhibits the carcinogenesis of lung adenocarcinoma by regulating PI3K-AKT signaling pathway. ( Han, X; Li, H; Lv, C; Wang, L; Wang, M, 2023) |
| "Emodin is an anthraquinone derivative originally isolated from Chinese rhubarb, possesses anticancer properties." | 5.46 | Emodin Inhibits ATP-Induced Proliferation and Migration by Suppressing P2Y Receptors in Human Lung Adenocarcinoma Cells. ( Guan, R; Li, L; Shen, L; Song, N; Wang, X; Zhu, D, 2017) |
| "This study investigated the mechanism of the cytotoxic effect of emodin, an active anthraquinone, on human lung adenocarcinoma A549 cells." | 3.80 | Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis. ( Chan, SW; Guo, DJ; Guo, ZD; Kwan, YW; Lee, SM; Leung, GP; Li, WY; Ng, YF; Yu, PH; Zhang, H, 2014) |
| "Lung adenocarcinoma is the most common type of lung cancer." | 1.91 | The ethyl acetate extract of Wenxia Changfu Formula inhibits the carcinogenesis of lung adenocarcinoma by regulating PI3K-AKT signaling pathway. ( Han, X; Li, H; Lv, C; Wang, L; Wang, M, 2023) |
| "Emodin is an anthraquinone derivative originally isolated from Chinese rhubarb, possesses anticancer properties." | 1.46 | Emodin Inhibits ATP-Induced Proliferation and Migration by Suppressing P2Y Receptors in Human Lung Adenocarcinoma Cells. ( Guan, R; Li, L; Shen, L; Song, N; Wang, X; Zhu, D, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, L | 1 |
| Han, X | 1 |
| Li, H | 1 |
| Lv, C | 1 |
| Wang, M | 1 |
| Teng, X | 1 |
| Wang, SY | 1 |
| Shi, YQ | 1 |
| Fan, XF | 1 |
| Liu, S | 1 |
| Xing, Y | 1 |
| Guo, YY | 1 |
| Dong, M | 1 |
| Wang, X | 1 |
| Li, L | 1 |
| Guan, R | 1 |
| Zhu, D | 1 |
| Song, N | 1 |
| Shen, L | 1 |
| Iyer, VV | 1 |
| Priya, PY | 1 |
| Kangeyavelu, J | 1 |
| Li, WY | 1 |
| Ng, YF | 1 |
| Zhang, H | 1 |
| Guo, ZD | 1 |
| Guo, DJ | 1 |
| Kwan, YW | 1 |
| Leung, GP | 1 |
| Lee, SM | 1 |
| Yu, PH | 1 |
| Chan, SW | 1 |
5 other studies available for emodin and Adenocarcinoma of Lung
| Article | Year |
|---|---|
The ethyl acetate extract of Wenxia Changfu Formula inhibits the carcinogenesis of lung adenocarcinoma by regulating PI3K-AKT signaling pathway.
Topics: Adenocarcinoma of Lung; Carcinogenesis; Emodin; Humans; Lung Neoplasms; Matrix Metalloproteinase 3; | 2023 |
The role of emodin on cisplatin resistance reversal of lung adenocarcinoma A549/DDP cell.
Topics: A549 Cells; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transport | 2021 |
Emodin Inhibits ATP-Induced Proliferation and Migration by Suppressing P2Y Receptors in Human Lung Adenocarcinoma Cells.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Adenosine Triphosphate; bcl-2-Associated X Prote | 2017 |
Effects of increased accumulation of doxorubicin due to emodin on efflux transporter and LRP1 expression in lung adenocarcinoma and colorectal carcinoma cells.
Topics: A549 Cells; Adenocarcinoma of Lung; Carrier Proteins; Colorectal Neoplasms; Doxorubicin; Emodin; Hum | 2018 |
Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Checkpo | 2014 |