emedastine has been researched along with Renal Insufficiency in 1 studies
emedastine: structure given in first source
emedastine : 1-Methyl-1,4-diazepane in which the hydrogen attached to the nitrogen at position 4 is substituted by a 1-(2-ethoxyethyl)-1H-benzimidazol-2-yl group. A relatively selective histamine H1 antagonist, it is used as the difumatate salt for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Emedastine difumarate is a new H1 receptor antagonist with well defined pharmacokinetic and pharmacodynamic profiles in healthy volunteers." | 2.70 | Pharmacokinetics of emedastine difumarate, a new anti-histaminic agent in patients with renal impairment. ( Assandri, A; Eichler, HG; Herranz, U; Joukhadar, C; Klein, N; Lackner, E; Müller, M; Pernerstorfer, T; Schrolnberger, C, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joukhadar, C | 1 |
| Herranz, U | 1 |
| Pernerstorfer, T | 1 |
| Assandri, A | 1 |
| Klein, N | 1 |
| Schrolnberger, C | 1 |
| Lackner, E | 1 |
| Eichler, HG | 1 |
| Müller, M | 1 |
1 trial available for emedastine and Renal Insufficiency
| Article | Year |
|---|---|
Pharmacokinetics of emedastine difumarate, a new anti-histaminic agent in patients with renal impairment.
Topics: Administration, Oral; Adult; Area Under Curve; Benzimidazoles; Female; Half-Life; Histamine H1 Antag | 2001 |