emedastine has been researched along with Conjunctivitis in 3 studies
emedastine: structure given in first source
emedastine : 1-Methyl-1,4-diazepane in which the hydrogen attached to the nitrogen at position 4 is substituted by a 1-(2-ethoxyethyl)-1H-benzimidazol-2-yl group. A relatively selective histamine H1 antagonist, it is used as the difumatate salt for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.
Conjunctivitis: INFLAMMATION of the CONJUNCTIVA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of this study suggest that emedastine and ketotifen are not significantly different with respect to anti-itching efficacy in the CAC model of acute allergic conjunctivitis." | 5.10 | Randomized, double-masked, placebo-controlled comparison of the efficacy of emedastine difumarate 0.05% ophthalmic solution and ketotifen fumarate 0.025% ophthalmic solution in the human conjunctival allergen challenge model. ( Bensch, G; D'Arienzo, PA; Leonardi, A, 2002) |
| "In this study, emedastine was more efficacious than loratadine for reducing the itching and redness associated with allergic conjunctivitis in the human conjunctival allergen challenge model." | 5.10 | A randomized, double-blind, placebo-controlled comparison of emedastine 0.05% ophthalmic solution with loratadine 10 mg and their combination in the human conjunctival allergen challenge model. ( Abelson, MB; Kaplan, AP, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blondin, C | 1 |
| Cholley, B | 1 |
| Haeffner-Cavaillon, N | 1 |
| Goldschmidt, P | 1 |
| D'Arienzo, PA | 1 |
| Leonardi, A | 1 |
| Bensch, G | 1 |
| Abelson, MB | 1 |
| Kaplan, AP | 1 |
2 trials available for emedastine and Conjunctivitis
| Article | Year |
|---|---|
Randomized, double-masked, placebo-controlled comparison of the efficacy of emedastine difumarate 0.05% ophthalmic solution and ketotifen fumarate 0.025% ophthalmic solution in the human conjunctival allergen challenge model.
Topics: Allergens; Anti-Allergic Agents; Benzimidazoles; Conjunctivitis; Double-Blind Method; Eye Color; Fem | 2002 |
A randomized, double-blind, placebo-controlled comparison of emedastine 0.05% ophthalmic solution with loratadine 10 mg and their combination in the human conjunctival allergen challenge model.
Topics: Adult; Allergens; Anti-Allergic Agents; Benzimidazoles; Conjunctivitis; Double-Blind Method; Drug Th | 2002 |
1 other study available for emedastine and Conjunctivitis
| Article | Year |
|---|---|
[In vitro effects of antiallergic eyedrops on complement activation induced by particulate matter].
Topics: Air Pollutants; Anti-Allergic Agents; Benzalkonium Compounds; Benzimidazoles; Complement Activation; | 2003 |