emd 53998 has been researched along with Cardiac Failure in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Fuhrer, W; Herold, P; Herzig, JW; Leutert, T; Meier, M; Rihs, G; Schenker, K; Stutz, S; Wenk, P; Zbinden, P | 1 |
| Irving, T; Jani, V; Ma, W; Qian, W; Yuan, S | 1 |
| Andersen, GØ; Ata, SH; Dahl, CP; Levy, FO; Orstavik, O; Osnes, JB; Qvigstad, E; Riise, J; Skomedal, T | 1 |
| Endoh, M | 1 |
| Borbély, A; Edes, I; Papp, Z; Stienen, GJ; Van Der Velden, J | 1 |
| Brixius, K; Schwinger, RH | 1 |
| Gwathmey, JK; Hajjar, RJ; Helm, P; Schmidt, U | 1 |
| Holubarsch, C | 1 |
| Allen, DG; Lee, JA | 1 |
| Arimura, K; Egashira, K; Ide, T; Kinugawa, S; Nakamura, R; Takeshita, A; Tsutsui, H | 1 |
| Atsumi, H; Endoh, M; Nakada, S; Sakurai, K; Sugawara, H; Tomoike, H | 1 |
| Egashira, K; Makino, N; Satoh, S; Suematsu, N; Takeshita, A; Tsutsui, H; Ueda, Y | 1 |
3 review(s) available for emd 53998 and Cardiac Failure
| Article | Year |
|---|---|
Cardiac Ca2+ signaling and Ca2+ sensitizers.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Angiotensin II; Animals; Azocines; Calcium; Calcium Signaling; Cardiotonic Agents; Cholinergic Agonists; Dihydropyridines; Endothelins; Heart Failure; Humans; Hydrazones; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Pyridazines; Quinolines; Simendan; Thiadiazines; Troponin C | 2008 |
[If the myofilaments become sensitive: Ca2+-sensitizer for the therapy of heart insufficiency].
Topics: Actin Cytoskeleton; Calcium; Cardiotonic Agents; Heart; Heart Failure; Humans; Hydrazones; Myocardium; Oxygen Consumption; Pyridazines; Quinolines; Simendan; Thiadiazines | 2005 |
Calcium sensitisers: mechanisms of action and potential usefulness as inotropes.
Topics: Animals; Calcium; Cardiotonic Agents; Heart Failure; Humans; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Quinolines; Thiadiazines | 1997 |
9 other study(ies) available for emd 53998 and Cardiac Failure
| Article | Year |
|---|---|
5-Methyl-6-phenyl-1,3,5,6-tetrahydro-3,6-methano-1,5-benzodiazocine-2,4-dione (BA 41899): representative of a novel class of purely calcium-sensitizing agents.
Topics: Animals; Azocines; Calcium; Cardiotonic Agents; Electric Stimulation; Guinea Pigs; Heart Atria; Heart Failure; Imidazoles; In Vitro Techniques; Isometric Contraction; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Sensitivity and Specificity; Stereoisomerism; Swine | 1995 |
EMD-57033 Augments the Contractility in Porcine Myocardium by Promoting the Activation of Myosin in Thick Filaments.
Topics: Animals; Heart Failure; Myocardium; Myocytes, Cardiac; Myosins; Swine; Troponin | 2022 |
Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiotonic Agents; Heart; Heart Failure; Humans; Hydrazones; In Vitro Techniques; Isoproterenol; Male; Milrinone; Myocardial Contraction; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 4 Inhibitors; Pyridazines; Quinolines; Quinolones; Rats, Wistar; Rolipram; Simendan; Thiadiazines | 2014 |
Effects of Ca2+ -sensitizers in permeabilized cardiac myocytes from donor and end-stage failing human hearts.
Topics: Acetamides; Adult; Aged; Calcium; Cell Membrane Permeability; Female; Heart Failure; Humans; In Vitro Techniques; Male; Middle Aged; Myocardium; Myocytes, Cardiac; Pyridazines; Quinolines; Thiadiazines; Tissue Donors | 2004 |
Ca++ sensitizers impair cardiac relaxation in failing human myocardium.
Topics: Adult; Calcium; Cardiotonic Agents; Diastole; Dose-Response Relationship, Drug; Female; Heart Failure; Humans; Male; Middle Aged; Myocardial Contraction; Organic Chemicals; Quinolines; Thiadiazines | 1997 |
New inotropic concepts: rationale for and differences between calcium sensitizers and phosphodiesterase inhibitors.
Topics: Animals; Calcium; Cardiotonic Agents; Deoxyepinephrine; Energy Metabolism; Guinea Pigs; Heart Failure; Humans; Imidazoles; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Papillary Muscles; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Quinolines; Thiadiazines | 1997 |
Positive inotropic effect of insulin-like growth factor-1 on normal and failing cardiac myocytes.
Topics: Actin Cytoskeleton; Analysis of Variance; Animals; Calcium; Cardiac Pacing, Artificial; Cell Size; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diacetyl; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Growth Hormone; Heart Failure; Homeostasis; In Vitro Techniques; Insulin-Like Growth Factor I; Myocardial Contraction; Myocardium; Quinolines; Stimulation, Chemical; Thiadiazines | 1999 |
Differential alteration of cardiotonic effects of EMD 57033 and beta-adrenoceptor agonists in volume-overload rabbit ventricular myocytes.
Topics: Adrenergic beta-Agonists; Animals; Cardiomegaly; Cardiotonic Agents; Disease Models, Animal; Dobutamine; Drug Evaluation, Preclinical; Electrocardiography; Heart Failure; Hemodynamics; Isoproterenol; Male; Myocardial Contraction; Myofibrils; Phosphodiesterase Inhibitors; Quinolines; Rabbits; Thiadiazines | 2000 |
Post-beta-receptor impairment in the regulation of myofibrillar Ca2+ sensitivity in tachypacing-induced canine failing heart.
Topics: Animals; Blotting, Western; Calcium; Cell Size; Cyclic AMP; Dogs; Electrophoresis, Polyacrylamide Gel; Heart Failure; Myocardial Contraction; Myocardium; Myofibrils; Pacemaker, Artificial; Phosphodiesterase Inhibitors; Phosphorylation; Quinolines; Receptors, Adrenergic, beta; Signal Transduction; Thiadiazines; Troponin I; Ventricular Function, Left | 2002 |