Page last updated: 2024-10-26

embelin and Leukemia, Myeloid, Acute

embelin has been researched along with Leukemia, Myeloid, Acute in 2 studies

embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research Excerpts

ExcerptRelevanceReference
"Embelin is a potent XIAP inhibitor which has been shown to inhibit the proliferation of tumor cells and cause cell apoptosis."1.42Embelin sensitizes acute myeloid leukemia cells to TRAIL through XIAP inhibition and NF-κB inactivation. ( Chen, X; Huang, Q; Jin, T; Lan, J; Liu, X; Mou, X; Sun, X; Wang, S; Yang, P; Yang, T, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Reis-Silva, CSM1
Branco, PC1
Lima, K1
Silva, FL1
Moreno, PRH1
Guallar, V1
Costa-Lotufo, LV1
Machado-Neto, JA1
Yang, T1
Lan, J1
Huang, Q1
Chen, X1
Sun, X1
Liu, X1
Yang, P1
Jin, T1
Wang, S1
Mou, X1

Other Studies

2 other studies available for embelin and Leukemia, Myeloid, Acute

ArticleYear
Embelin potentiates venetoclax-induced apoptosis in acute myeloid leukemia cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2021, Volume: 76

    Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Bridged Bicyclo Compounds, Heterocyclic; Cell Line,

2021
Embelin sensitizes acute myeloid leukemia cells to TRAIL through XIAP inhibition and NF-κB inactivation.
    Cell biochemistry and biophysics, 2015, Volume: 71, Issue:1

    Topics: Adenoviridae; Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Female; HL-60 Cells; Humans;

2015