embelin has been researched along with Leukemia, Myeloid, Acute in 2 studies
embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Embelin is a potent XIAP inhibitor which has been shown to inhibit the proliferation of tumor cells and cause cell apoptosis." | 1.42 | Embelin sensitizes acute myeloid leukemia cells to TRAIL through XIAP inhibition and NF-κB inactivation. ( Chen, X; Huang, Q; Jin, T; Lan, J; Liu, X; Mou, X; Sun, X; Wang, S; Yang, P; Yang, T, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reis-Silva, CSM | 1 |
| Branco, PC | 1 |
| Lima, K | 1 |
| Silva, FL | 1 |
| Moreno, PRH | 1 |
| Guallar, V | 1 |
| Costa-Lotufo, LV | 1 |
| Machado-Neto, JA | 1 |
| Yang, T | 1 |
| Lan, J | 1 |
| Huang, Q | 1 |
| Chen, X | 1 |
| Sun, X | 1 |
| Liu, X | 1 |
| Yang, P | 1 |
| Jin, T | 1 |
| Wang, S | 1 |
| Mou, X | 1 |
2 other studies available for embelin and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Embelin potentiates venetoclax-induced apoptosis in acute myeloid leukemia cells.
Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, | 2021 |
Embelin sensitizes acute myeloid leukemia cells to TRAIL through XIAP inhibition and NF-κB inactivation.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Female; HL-60 Cells; Humans; | 2015 |