embelin has been researched along with Leucocythaemia in 3 studies
embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was designed to explore the effects of low-toxicity Embelin on TRAIL-induced apoptosis and its possible mechanism in human leukemia cells." | 7.81 | The XIAP inhibitor Embelin enhances TRAIL-induced apoptosis in human leukemia cells by DR4 and DR5 upregulation. ( Hu, R; Jiang, H; Li, J; Liu, Z; Xu, W; Yang, Y; Zhu, K, 2015) |
| "The present study was undertaken to determine the molecular mechanisms by which embelin induces apoptosis in human leukemia cells." | 7.77 | Embelin induces apoptosis through down-regulation of XIAP in human leukemia cells. ( Hu, R; Li, Y; Liu, Z; Wang, H; Yang, W; Yao, K; Zhang, R; Zhu, K, 2011) |
| "The present study was designed to explore the effects of low-toxicity Embelin on TRAIL-induced apoptosis and its possible mechanism in human leukemia cells." | 3.81 | The XIAP inhibitor Embelin enhances TRAIL-induced apoptosis in human leukemia cells by DR4 and DR5 upregulation. ( Hu, R; Jiang, H; Li, J; Liu, Z; Xu, W; Yang, Y; Zhu, K, 2015) |
| "The present study was undertaken to determine the molecular mechanisms by which embelin induces apoptosis in human leukemia cells." | 3.77 | Embelin induces apoptosis through down-regulation of XIAP in human leukemia cells. ( Hu, R; Li, Y; Liu, Z; Wang, H; Yang, W; Yao, K; Zhang, R; Zhu, K, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prabhu, KS | 1 |
| Siveen, KS | 1 |
| Kuttikrishnan, S | 1 |
| Iskandarani, A | 1 |
| Tsakou, M | 1 |
| Achkar, IW | 1 |
| Therachiyil, L | 1 |
| Krishnankutty, R | 1 |
| Parray, A | 1 |
| Kulinski, M | 1 |
| Merhi, M | 1 |
| Dermime, S | 1 |
| Mohammad, RM | 1 |
| Uddin, S | 1 |
| Hu, R | 2 |
| Yang, Y | 1 |
| Liu, Z | 2 |
| Jiang, H | 1 |
| Zhu, K | 2 |
| Li, J | 1 |
| Xu, W | 1 |
| Li, Y | 1 |
| Yao, K | 1 |
| Zhang, R | 1 |
| Wang, H | 1 |
| Yang, W | 1 |
3 other studies available for embelin and Leucocythaemia
| Article | Year |
|---|---|
Targeting of X-linked inhibitor of apoptosis protein and PI3-kinase/AKT signaling by embelin suppresses growth of leukemic cells.
Topics: Benzoquinones; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Drug Synergism; Gene | 2017 |
The XIAP inhibitor Embelin enhances TRAIL-induced apoptosis in human leukemia cells by DR4 and DR5 upregulation.
Topics: Apoptosis; Benzoquinones; Caspases; Cell Proliferation; Gene Expression Regulation, Leukemic; HL-60 | 2015 |
Embelin induces apoptosis through down-regulation of XIAP in human leukemia cells.
Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Blotting, Western; Caspases; Cell Line, Tumor; Cell | 2011 |