embelin has been researched along with Intervertebral Disc Degeneration in 1 studies
embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.
Intervertebral Disc Degeneration: Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Embelin treatment caused inhibitory effects on the IL-1β-stimulated production of COX-2, IL-6, IL-8, and TNF-α, which were abolished by LY294002 treatment." | 5.91 | Embelin protects against apoptosis and inflammation by regulating PI3K/Akt signaling in IL-1β-stimulated human nucleus pulposus cells. ( Bai, X; Ding, S; Guo, S; Jiang, M; Mu, W; Pei, B; Wang, J; Yang, S; Yao, M; Zhang, M; Zhu, X, 2023) |
| "Embelin treatment caused inhibitory effects on the IL-1β-stimulated production of COX-2, IL-6, IL-8, and TNF-α, which were abolished by LY294002 treatment." | 1.91 | Embelin protects against apoptosis and inflammation by regulating PI3K/Akt signaling in IL-1β-stimulated human nucleus pulposus cells. ( Bai, X; Ding, S; Guo, S; Jiang, M; Mu, W; Pei, B; Wang, J; Yang, S; Yao, M; Zhang, M; Zhu, X, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, X | 1 |
| Wang, J | 1 |
| Ding, S | 1 |
| Yang, S | 1 |
| Pei, B | 1 |
| Yao, M | 1 |
| Zhu, X | 1 |
| Jiang, M | 1 |
| Zhang, M | 1 |
| Mu, W | 1 |
| Guo, S | 1 |
1 other study available for embelin and Intervertebral Disc Degeneration
| Article | Year |
|---|---|
Embelin protects against apoptosis and inflammation by regulating PI3K/Akt signaling in IL-1β-stimulated human nucleus pulposus cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Benzoquinones; Caspase 3; Cells, Cultured; Cyclooxygenase 2; | 2023 |