embelin has been researched along with Glioma in 3 studies
embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Embelin is an active compound identified as a novel XIAP inhibitor from the Embelia ribes that exhibits various medicinal effects including anti-inflammatory and anti-cancer activities." | 5.39 | Embelin induces apoptosis in human glioma cells through inactivating NF-κB. ( Ahn, KS; Jang, HJ; Kim, SH; Lee, JH; Lee, SG; Lim, SL; Park, SY; Um, JY, 2013) |
| "Brain glioma is the most common malignant intracranial tumor and has become the focus of research on diseases of the central nervous system due to its high incidence and poor prognosis." | 5.39 | Embelin-induced brain glioma cell apoptosis and cell cycle arrest via the mitochondrial pathway. ( Wang, A; Wu, W; Zhang, B; Zhang, J, 2013) |
| "Embelin has been reported to exhibit therapeutic activity in cancer." | 5.35 | The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP. ( Gaiser, T; Siegelin, MD; Siegelin, Y, 2009) |
| "Embelin is an active compound identified as a novel XIAP inhibitor from the Embelia ribes that exhibits various medicinal effects including anti-inflammatory and anti-cancer activities." | 1.39 | Embelin induces apoptosis in human glioma cells through inactivating NF-κB. ( Ahn, KS; Jang, HJ; Kim, SH; Lee, JH; Lee, SG; Lim, SL; Park, SY; Um, JY, 2013) |
| "Brain glioma is the most common malignant intracranial tumor and has become the focus of research on diseases of the central nervous system due to its high incidence and poor prognosis." | 1.39 | Embelin-induced brain glioma cell apoptosis and cell cycle arrest via the mitochondrial pathway. ( Wang, A; Wu, W; Zhang, B; Zhang, J, 2013) |
| "Embelin has been reported to exhibit therapeutic activity in cancer." | 1.35 | The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP. ( Gaiser, T; Siegelin, MD; Siegelin, Y, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, SY | 1 |
| Lim, SL | 1 |
| Jang, HJ | 1 |
| Lee, JH | 1 |
| Um, JY | 1 |
| Kim, SH | 1 |
| Ahn, KS | 1 |
| Lee, SG | 1 |
| Wang, A | 1 |
| Zhang, B | 1 |
| Zhang, J | 1 |
| Wu, W | 2 |
| Siegelin, MD | 1 |
| Gaiser, T | 1 |
| Siegelin, Y | 1 |
3 other studies available for embelin and Glioma
| Article | Year |
|---|---|
Embelin induces apoptosis in human glioma cells through inactivating NF-κB.
Topics: Apoptosis; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Glioma; Humans; NF-kappa B | 2013 |
Embelin-induced brain glioma cell apoptosis and cell cycle arrest via the mitochondrial pathway.
Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Caspases; Cell Cycle Checkpoints; Cell Cycle Protei | 2013 |
The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulato | 2009 |