Page last updated: 2024-10-26

embelin and Glioma

embelin has been researched along with Glioma in 3 studies

embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Embelin is an active compound identified as a novel XIAP inhibitor from the Embelia ribes that exhibits various medicinal effects including anti-inflammatory and anti-cancer activities."5.39Embelin induces apoptosis in human glioma cells through inactivating NF-κB. ( Ahn, KS; Jang, HJ; Kim, SH; Lee, JH; Lee, SG; Lim, SL; Park, SY; Um, JY, 2013)
"Brain glioma is the most common malignant intracranial tumor and has become the focus of research on diseases of the central nervous system due to its high incidence and poor prognosis."5.39Embelin-induced brain glioma cell apoptosis and cell cycle arrest via the mitochondrial pathway. ( Wang, A; Wu, W; Zhang, B; Zhang, J, 2013)
"Embelin has been reported to exhibit therapeutic activity in cancer."5.35The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP. ( Gaiser, T; Siegelin, MD; Siegelin, Y, 2009)
"Embelin is an active compound identified as a novel XIAP inhibitor from the Embelia ribes that exhibits various medicinal effects including anti-inflammatory and anti-cancer activities."1.39Embelin induces apoptosis in human glioma cells through inactivating NF-κB. ( Ahn, KS; Jang, HJ; Kim, SH; Lee, JH; Lee, SG; Lim, SL; Park, SY; Um, JY, 2013)
"Brain glioma is the most common malignant intracranial tumor and has become the focus of research on diseases of the central nervous system due to its high incidence and poor prognosis."1.39Embelin-induced brain glioma cell apoptosis and cell cycle arrest via the mitochondrial pathway. ( Wang, A; Wu, W; Zhang, B; Zhang, J, 2013)
"Embelin has been reported to exhibit therapeutic activity in cancer."1.35The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP. ( Gaiser, T; Siegelin, MD; Siegelin, Y, 2009)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, SY1
Lim, SL1
Jang, HJ1
Lee, JH1
Um, JY1
Kim, SH1
Ahn, KS1
Lee, SG1
Wang, A1
Zhang, B1
Zhang, J1
Wu, W2
Siegelin, MD1
Gaiser, T1
Siegelin, Y1

Other Studies

3 other studies available for embelin and Glioma

ArticleYear
Embelin induces apoptosis in human glioma cells through inactivating NF-κB.
    Journal of pharmacological sciences, 2013, Volume: 121, Issue:3

    Topics: Apoptosis; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Glioma; Humans; NF-kappa B

2013
Embelin-induced brain glioma cell apoptosis and cell cycle arrest via the mitochondrial pathway.
    Oncology reports, 2013, Volume: 29, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Caspases; Cell Cycle Checkpoints; Cell Cycle Protei

2013
The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP.
    Neurochemistry international, 2009, Volume: 55, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulato

2009