Page last updated: 2024-10-26

embelin and Degenerative Disc Disease

embelin has been researched along with Degenerative Disc Disease in 1 studies

embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.

Research Excerpts

ExcerptRelevanceReference
"Embelin treatment caused inhibitory effects on the IL-1β-stimulated production of COX-2, IL-6, IL-8, and TNF-α, which were abolished by LY294002 treatment."5.91Embelin protects against apoptosis and inflammation by regulating PI3K/Akt signaling in IL-1β-stimulated human nucleus pulposus cells. ( Bai, X; Ding, S; Guo, S; Jiang, M; Mu, W; Pei, B; Wang, J; Yang, S; Yao, M; Zhang, M; Zhu, X, 2023)
"Embelin treatment caused inhibitory effects on the IL-1β-stimulated production of COX-2, IL-6, IL-8, and TNF-α, which were abolished by LY294002 treatment."1.91Embelin protects against apoptosis and inflammation by regulating PI3K/Akt signaling in IL-1β-stimulated human nucleus pulposus cells. ( Bai, X; Ding, S; Guo, S; Jiang, M; Mu, W; Pei, B; Wang, J; Yang, S; Yao, M; Zhang, M; Zhu, X, 2023)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Bai, X1
Wang, J1
Ding, S1
Yang, S1
Pei, B1
Yao, M1
Zhu, X1
Jiang, M1
Zhang, M1
Mu, W1
Guo, S1

Other Studies

1 other study available for embelin and Degenerative Disc Disease

ArticleYear
Embelin protects against apoptosis and inflammation by regulating PI3K/Akt signaling in IL-1β-stimulated human nucleus pulposus cells.
    Tissue & cell, 2023, Volume: 82

    Topics: Apoptosis; bcl-2-Associated X Protein; Benzoquinones; Caspase 3; Cells, Cultured; Cyclooxygenase 2;

2023