Page last updated: 2024-10-26

embelin and Colonic Neoplasms

embelin has been researched along with Colonic Neoplasms in 4 studies

embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
" We previously reported that embelin suppresses colitis-associated tumorigenesis."7.83Macrophage targeting contributes to the inhibitory effects of embelin on colitis-associated cancer. ( Dai, Y; Jiao, H; Qiao, L; Shuai, X; Teng, G; Wang, W; Wu, T; Zhang, R; Zhao, P, 2016)
"Embelin is a small molecule inhibitor of X-linked inhibitor of apoptosis protein (XIAP), with antioxidant, anti-inflammatory, and antitumor activities."5.40Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling. ( Dai, Y; George, J; Hebbard, L; Jiao, H; Qiao, L; Teng, G; Wang, W; Wang, Y; Zhang, R, 2014)
" We previously reported that embelin suppresses colitis-associated tumorigenesis."3.83Macrophage targeting contributes to the inhibitory effects of embelin on colitis-associated cancer. ( Dai, Y; Jiao, H; Qiao, L; Shuai, X; Teng, G; Wang, W; Wu, T; Zhang, R; Zhao, P, 2016)
"Embelin is a small molecule inhibitor of X-linked inhibitor of apoptosis protein (XIAP), with antioxidant, anti-inflammatory, and antitumor activities."1.40Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling. ( Dai, Y; George, J; Hebbard, L; Jiao, H; Qiao, L; Teng, G; Wang, W; Wang, Y; Zhang, R, 2014)
"injected to induce colon cancer in PPARgamma(+/+) and PPARgamma(+/-) mice."1.35Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis. ( Chan, KW; Dai, Y; Gu, Q; Lan, HY; Ma, J; Pang, R; Qiao, L; Wang, J; Wong, BC; Yang, M; Ye, J; Zou, B, 2009)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dai, Y3
Jiao, H2
Teng, G2
Wang, W2
Zhang, R2
Wang, Y1
Hebbard, L1
George, J1
Qiao, L3
Wu, T1
Shuai, X1
Zhao, P1
Sumalatha, K1
Gowda, M1
Meenakshisundaram, S1
Chan, KW1
Yang, M1
Ye, J1
Ma, J1
Zou, B1
Gu, Q1
Wang, J1
Pang, R1
Lan, HY1
Wong, BC1

Other Studies

4 other studies available for embelin and Colonic Neoplasms

ArticleYear
Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:5

    Topics: Animals; Benzoquinones; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Cell Trans

2014
Macrophage targeting contributes to the inhibitory effects of embelin on colitis-associated cancer.
    Oncotarget, 2016, Apr-12, Volume: 7, Issue:15

    Topics: Animals; Benzoquinones; Cell Transformation, Neoplastic; Cells, Cultured; Colitis; Colon; Colonic Ne

2016
ROS-mediated induction of apoptosis by benzoquinone embelin in human colon adenocarcinoma cells HT-29.
    Journal of complementary & integrative medicine, 2017, Mar-16, Volume: 14, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Benzoquinones; Cell Line, Tumor; Colon

2017
Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis.
    Cancer research, 2009, Jun-01, Volume: 69, Issue:11

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Cell Proliferation; Coloni

2009