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embelin and Cell Transformation, Neoplastic

embelin has been researched along with Cell Transformation, Neoplastic in 2 studies

embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
" We previously reported that embelin suppresses colitis-associated tumorigenesis."7.83Macrophage targeting contributes to the inhibitory effects of embelin on colitis-associated cancer. ( Dai, Y; Jiao, H; Qiao, L; Shuai, X; Teng, G; Wang, W; Wu, T; Zhang, R; Zhao, P, 2016)
"Embelin is a small molecule inhibitor of X-linked inhibitor of apoptosis protein (XIAP), with antioxidant, anti-inflammatory, and antitumor activities."5.40Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling. ( Dai, Y; George, J; Hebbard, L; Jiao, H; Qiao, L; Teng, G; Wang, W; Wang, Y; Zhang, R, 2014)
" We previously reported that embelin suppresses colitis-associated tumorigenesis."3.83Macrophage targeting contributes to the inhibitory effects of embelin on colitis-associated cancer. ( Dai, Y; Jiao, H; Qiao, L; Shuai, X; Teng, G; Wang, W; Wu, T; Zhang, R; Zhao, P, 2016)
"Embelin is a small molecule inhibitor of X-linked inhibitor of apoptosis protein (XIAP), with antioxidant, anti-inflammatory, and antitumor activities."1.40Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling. ( Dai, Y; George, J; Hebbard, L; Jiao, H; Qiao, L; Teng, G; Wang, W; Wang, Y; Zhang, R, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dai, Y2
Jiao, H2
Teng, G2
Wang, W2
Zhang, R2
Wang, Y1
Hebbard, L1
George, J1
Qiao, L2
Wu, T1
Shuai, X1
Zhao, P1

Other Studies

2 other studies available for embelin and Cell Transformation, Neoplastic

ArticleYear
Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:5

    Topics: Animals; Benzoquinones; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Cell Trans

2014
Macrophage targeting contributes to the inhibitory effects of embelin on colitis-associated cancer.
    Oncotarget, 2016, Apr-12, Volume: 7, Issue:15

    Topics: Animals; Benzoquinones; Cell Transformation, Neoplastic; Cells, Cultured; Colitis; Colon; Colonic Ne

2016