Page last updated: 2024-10-26

embelin and Brain Ischemia

embelin has been researched along with Brain Ischemia in 2 studies

embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Embelin treatment has significantly protected synaptic plasticity impairment as assessed by hippocampal long-term potentiation (LTP) test."1.51Embelin Improves the Spatial Memory and Hippocampal Long-Term Potentiation in a Rat Model of Chronic Cerebral Hypoperfusion. ( Bakar, SNS; Bhuvanendran, S; Hassan, Z; Kumari, Y; Othman, I; Shaikh, MF, 2019)
"Embelin treatment significantly exacerbated stroke-induced injury in females but had no effect in males, demonstrating that XIAP is an important mediator of sex-specific responses after stroke."1.37miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia. ( Benashski, SE; Li, J; Liu, F; McCullough, LD; Siegel, C, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhuvanendran, S1
Bakar, SNS1
Kumari, Y1
Othman, I1
Shaikh, MF1
Hassan, Z1
Siegel, C1
Li, J1
Liu, F1
Benashski, SE1
McCullough, LD1

Other Studies

2 other studies available for embelin and Brain Ischemia

ArticleYear
Embelin Improves the Spatial Memory and Hippocampal Long-Term Potentiation in a Rat Model of Chronic Cerebral Hypoperfusion.
    Scientific reports, 2019, 10-10, Volume: 9, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Benzoquinones; Brain Ischemia; Brain-Der

2019
miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Jul-12, Volume: 108, Issue:28

    Topics: 3' Untranslated Regions; Animals; Apoptosis Regulatory Proteins; Base Sequence; Benzoquinones; Bindi

2011