embelin has been researched along with Brain Ischemia in 2 studies
embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Embelin treatment has significantly protected synaptic plasticity impairment as assessed by hippocampal long-term potentiation (LTP) test." | 1.51 | Embelin Improves the Spatial Memory and Hippocampal Long-Term Potentiation in a Rat Model of Chronic Cerebral Hypoperfusion. ( Bakar, SNS; Bhuvanendran, S; Hassan, Z; Kumari, Y; Othman, I; Shaikh, MF, 2019) |
| "Embelin treatment significantly exacerbated stroke-induced injury in females but had no effect in males, demonstrating that XIAP is an important mediator of sex-specific responses after stroke." | 1.37 | miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia. ( Benashski, SE; Li, J; Liu, F; McCullough, LD; Siegel, C, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhuvanendran, S | 1 |
| Bakar, SNS | 1 |
| Kumari, Y | 1 |
| Othman, I | 1 |
| Shaikh, MF | 1 |
| Hassan, Z | 1 |
| Siegel, C | 1 |
| Li, J | 1 |
| Liu, F | 1 |
| Benashski, SE | 1 |
| McCullough, LD | 1 |
2 other studies available for embelin and Brain Ischemia
| Article | Year |
|---|---|
Embelin Improves the Spatial Memory and Hippocampal Long-Term Potentiation in a Rat Model of Chronic Cerebral Hypoperfusion.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Benzoquinones; Brain Ischemia; Brain-Der | 2019 |
miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia.
Topics: 3' Untranslated Regions; Animals; Apoptosis Regulatory Proteins; Base Sequence; Benzoquinones; Bindi | 2011 |