Page last updated: 2024-10-26

embelin and Alloxan Diabetes

embelin has been researched along with Alloxan Diabetes in 6 studies

embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.

Research Excerpts

ExcerptRelevanceReference
"These findings show that embelin could improve adipose tissue insulin sensitivity without increasing weight gain, enhance glycemic control, protect β-cell from damage and maintain glucose homeostasis in adipose tissue."3.79Insulin sensitization via partial agonism of PPARγ and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in type 2 diabetic rats. ( Balakrishna, K; Gandhi, GR; Ignacimuthu, S; Paulraj, MG; Stalin, A; Vishal, R, 2013)
"Embelin is a natural compound possessing a plethora of pharmacological activities, including antidiabetic activity."1.48Embelin-loaded oral niosomes ameliorate streptozotocin-induced diabetes in Wistar rats. ( Abidin, L; Ahad, A; Alam, MS; Aqil, M; Mir, SR; Mujeeb, M, 2018)
"Embelin treatment to HFD+STZ diabetic rats also improved the altered histoarchitecture of β-islets of pancreas and hepatocytes."1.39Anti-diabetic activity of embelin: involvement of cellular inflammatory mediators, oxidative stress and other biomarkers. ( Ansari, AA; Naik, SR; Niture, NT; Shah, PD, 2013)
"Embelin was also active by the oral route (25 and 50 mg/kg) in the incision and dead space wound models."1.39Embelin accelerates cutaneous wound healing in diabetic rats. ( Deshmukh, PT; Gupta, VB, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alam, MS1
Ahad, A1
Abidin, L1
Aqil, M1
Mir, SR1
Mujeeb, M1
Naik, SR1
Niture, NT1
Ansari, AA1
Shah, PD1
Wu, H1
Panakanti, R1
Li, F1
Mahato, RI1
Gupta, R1
Sharma, AK1
Sharma, MC1
Gupta, RS1
Gandhi, GR1
Stalin, A1
Balakrishna, K1
Ignacimuthu, S1
Paulraj, MG1
Vishal, R1
Deshmukh, PT1
Gupta, VB1

Other Studies

6 other studies available for embelin and Alloxan Diabetes

ArticleYear
Embelin-loaded oral niosomes ameliorate streptozotocin-induced diabetes in Wistar rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Administration, Oral; Animals; Antioxidants; Benzoquinones; Calorimetry, Differential Scanning; Diab

2018
Anti-diabetic activity of embelin: involvement of cellular inflammatory mediators, oxidative stress and other biomarkers.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Jul-15, Volume: 20, Issue:10

    Topics: Animals; Benzoquinones; Biomarkers; Diabetes Mellitus, Experimental; Embelia; Female; Hypoglycemic A

2013
XIAP gene expression protects β-cells and human islets from apoptotic cell death.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Apoptosis; Benzoquinones; Blood Glucose; Caspases; Cell Line; Cytokines; Diabetes Mellitus,

2010
Antioxidant activity and protection of pancreatic β-cells by embelin in streptozotocin-induced diabetes.
    Journal of diabetes, 2012, Volume: 4, Issue:3

    Topics: Animals; Antioxidants; Ascorbic Acid; Benzoquinones; Blood Glucose; Catalase; Diabetes Mellitus, Exp

2012
Insulin sensitization via partial agonism of PPARγ and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in type 2 diabetic rats.
    Biochimica et biophysica acta, 2013, Volume: 1830, Issue:1

    Topics: Adipose Tissue; Animals; Benzoquinones; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2;

2013
Embelin accelerates cutaneous wound healing in diabetic rats.
    Journal of Asian natural products research, 2013, Volume: 15, Issue:2

    Topics: Administration, Cutaneous; Animals; Benzoquinones; Diabetes Mellitus, Experimental; Disease Models,

2013