em 523 has been researched along with Muscle Contraction in 8 studies
*Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Itoh, Z; Koga, H; Omura, S; Ozaki, K; Takanashi, H; Yogo, K | 1 |
| Akima, M; Itoh, Z; Kamei, K; Koga, H; Omura, S; Onoma, M; Ozaki, K; Sudo, H; Takanashi, H; Yogo, K | 1 |
| Haga, N; Inatomi, N; Itoh, Z; Mizumoto, A; Shiba, Y; Yamamoto, O | 1 |
| Depoortere, I; Dharanipragada, R; Florance, JR; Galdes, A; Macielag, MJ; Marvin, MS; Peeters, TL | 1 |
| Inatomi, N; Mizuki, A; Sato, S; Shiba, Y; Yamamoto, O | 1 |
| Kitazawa, T; Ohga, A; Taneike, T | 1 |
| Matthijs, G; Peeters, TL; Vantrappen, G | 1 |
| Inatomi, N; Itoh, Z; Marui, S; Omura, S; Satoh, H; Satoh, T | 1 |
8 other study(ies) available for em 523 and Muscle Contraction
| Article | Year |
|---|---|
In vitro pharmacological characterization of mitemcinal (GM-611), the first acid-resistant non-peptide motilin receptor agonist, in smooth muscle of rabbit small intestine.
Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Calcium Chloride; Diltiazem; Dose-Response Relationship, Drug; Erythromycin; Hexamethonium; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Intestine, Small; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth; Naloxone; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Tetrodotoxin; Tropisetron; Verapamil | 2007 |
Effects of mitemcinal (GM-611), an acid-resistant nonpeptide motilin receptor agonist, on the gastrointestinal contractile activity in conscious dogs.
Topics: Administration, Oral; Animals; Digestion; Dogs; Dose-Response Relationship, Drug; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal Tract; Injections, Intravenous; Male; Motilin; Muscle Contraction; Muscle, Smooth; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide | 2007 |
Stimulatory mechanism of EM523-induced contractions in postprandial stomach of conscious dogs.
Topics: Animals; Anti-Bacterial Agents; Atropine; Dipeptides; Dogs; Dopamine; Eating; Erythromycin; Hexamethonium; Indoles; Motilin; Muscle Contraction; Naloxone; Ondansetron; Serotonin Antagonists; Stomach; Substance P | 1995 |
The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit.
Topics: Animals; Binding, Competitive; Digestive System; Duodenum; Erythromycin; Motilin; Muscle Contraction; Muscle, Smooth; Pyloric Antrum; Rabbits | 1994 |
[Mechanism of increased gastric motility effect of EM523].
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Eating; Erythromycin; Gastrointestinal Agents; Gastrointestinal Motility; Muscle Contraction; Muscle, Smooth; Stomach | 1995 |
Functional characterization of neural and smooth muscle motilin receptors in the chicken proventriculus and ileum.
Topics: Animals; Chickens; Dogs; Erythromycin; Gastrointestinal Agents; Hormones; Ileum; Motilin; Muscle Contraction; Muscle, Smooth; Proventriculus; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Swine | 1997 |
Ca2+ dependence of motilide-induced contractions in rabbit duodenal muscle strips in vitro.
Topics: Animals; Calcium; Duodenum; Erythromycin; In Vitro Techniques; Molecular Structure; Motilin; Muscle Contraction; Muscle, Smooth; Rabbits | 1991 |
EM-523, an erythromycin derivative, and motilin show similar contractile activity in isolated rabbit intestine.
Topics: Acetylcholine; Animals; Atropine; Dinoprost; Drug Interactions; Erythromycin; Female; Guinea Pigs; Intestine, Small; Male; Motilin; Muscle Contraction; Muscle, Smooth; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Tetrodotoxin | 1990 |