ellipticine has been researched along with Neoplasms in 12 studies
ellipticine : A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anticancer agents are critical for the cancer treatment, but side effects and the drug resistance associated with the currently used anticancer agents create an urgent need to explore novel drugs with low side effects and high efficacy." | 2.61 | 1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships. ( Liu, Y; Xu, Z; Zhao, SJ, 2019) |
| "Among the remaining tumors, although they may process a wild-type p53, the pathways of p53-induced cell-cycle arrest and apoptosis are deficient." | 2.44 | Restoration of p53 to limit tumor growth. ( El-Deiry, WS; Wang, W, 2008) |
| "The proposal is advanced that anti-cancer drugs generally function by charge transfer resulting in formation of toxic oxy radicals which destroy the neoplasm." | 2.37 | Charge transfer-oxy radical mechanism for anti-cancer agents. ( Ames, JR; Cox, O; Elo, H; Jackson, H; Kovacic, P; Lumme, P; Ramirez, L; Rivera, LA; Ryan, MD, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Willemann, C | 1 |
| Grünert, R | 1 |
| Bednarski, PJ | 1 |
| Troschütz, R | 1 |
| Queiroz, MJ | 1 |
| Peixoto, D | 1 |
| Calhelha, RC | 1 |
| Soares, P | 1 |
| Dos Santos, T | 1 |
| Lima, RT | 1 |
| Campos, JF | 1 |
| Abreu, RM | 1 |
| Ferreira, IC | 1 |
| Vasconcelos, MH | 1 |
| Ngo, QA | 1 |
| Nguyen, le A | 1 |
| Vo, NB | 1 |
| Nguyen, TH | 2 |
| Roussi, F | 1 |
| Nguyen, VT | 1 |
| Hongthong, S | 1 |
| Meesin, J | 1 |
| Pailee, P | 1 |
| Soorukram, D | 1 |
| Kongsaeree, P | 1 |
| Prabpai, S | 1 |
| Piyachaturawat, P | 1 |
| Jariyawat, S | 1 |
| Suksen, K | 1 |
| Jaipetch, T | 1 |
| Nuntasaen, N | 1 |
| Reutrakul, V | 1 |
| Kuhakarn, C | 1 |
| Le-Nhat-Thuy, G | 1 |
| Dinh, TV | 1 |
| Pham-The, H | 1 |
| Nguyen Quang, H | 1 |
| Nguyen Thi, N | 1 |
| Dang Thi, TA | 1 |
| Hoang Thi, P | 1 |
| Le Thi, TA | 1 |
| Nguyen, HT | 1 |
| Nguyen Thanh, P | 1 |
| Le Duc, T | 1 |
| Nguyen, TV | 1 |
| Xu, Z | 1 |
| Zhao, SJ | 1 |
| Liu, Y | 1 |
| Studenovský, M | 1 |
| Sedláček, O | 1 |
| Hrubý, M | 1 |
| Pánek, J | 1 |
| Ulbrich, K | 1 |
| Prudent, R | 1 |
| Moucadel, V | 1 |
| Nguyen, CH | 1 |
| Barette, C | 1 |
| Schmidt, F | 1 |
| Florent, JC | 1 |
| Lafanechère, L | 1 |
| Sautel, CF | 1 |
| Duchemin-Pelletier, E | 1 |
| Spreux, E | 1 |
| Filhol, O | 1 |
| Reiser, JB | 1 |
| Cochet, C | 1 |
| Garbett, NC | 1 |
| Graves, DE | 1 |
| Wang, W | 1 |
| El-Deiry, WS | 1 |
| Kovacic, P | 1 |
| Ames, JR | 1 |
| Lumme, P | 1 |
| Elo, H | 1 |
| Cox, O | 1 |
| Jackson, H | 1 |
| Rivera, LA | 1 |
| Ramirez, L | 1 |
| Ryan, MD | 1 |
4 reviews available for ellipticine and Neoplasms
| Article | Year |
|---|---|
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Tria | 2019 |
Extending nature's leads: the anticancer agent ellipticine.
Topics: Animals; Antineoplastic Agents; Apocynaceae; Ellipticines; Humans; Neoplasms; Phytotherapy; Structur | 2004 |
Restoration of p53 to limit tumor growth.
Topics: Antineoplastic Agents; Apoptosis; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle | 2008 |
Charge transfer-oxy radical mechanism for anti-cancer agents.
Topics: Alkylation; Antineoplastic Agents; Antioxidants; DNA; Ellipticines; Free Radicals; Mercaptopurine; M | 1986 |
8 other studies available for ellipticine and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Synthesis and cytotoxic activity of 5,6-heteroaromatically annulated pyridine-2,4-diamines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Diamines; Drug Screening Assays, Antitu | 2009 |
New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death.
Topics: Amines; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line; Cell Proliferation; Dose-Response R | 2013 |
Synthesis and antiproliferativeactivity of new vinca alkaloids containing an α,β-unsaturated aromatic side chain.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Humans; Inhibitory Concentration 50; Molecular | 2015 |
Cytotoxic lanostanes from fruits of Garcinia wallichii Choisy (Guttiferae).
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Fruit; Garcinia; Humans; Lanosterol; Models, Mo | 2016 |
Design, synthesis and evaluation of novel hybrids between 4-anilinoquinazolines and substituted triazoles as potent cytotoxic agents.
Topics: Amino Acid Sequence; Aniline Compounds; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug S | 2018 |
Multi-responsive polymer micelles as ellipticine delivery carriers for cancer therapy.
Topics: Antineoplastic Agents; Ellipticines; Half-Life; Hydrogen-Ion Concentration; Micelles; Neoplasms; Pol | 2015 |
Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carbazoles; Casei | 2010 |