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ellipticine and Neoplasms

ellipticine has been researched along with Neoplasms in 12 studies

ellipticine : A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Anticancer agents are critical for the cancer treatment, but side effects and the drug resistance associated with the currently used anticancer agents create an urgent need to explore novel drugs with low side effects and high efficacy."2.611,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships. ( Liu, Y; Xu, Z; Zhao, SJ, 2019)
"Among the remaining tumors, although they may process a wild-type p53, the pathways of p53-induced cell-cycle arrest and apoptosis are deficient."2.44Restoration of p53 to limit tumor growth. ( El-Deiry, WS; Wang, W, 2008)
"The proposal is advanced that anti-cancer drugs generally function by charge transfer resulting in formation of toxic oxy radicals which destroy the neoplasm."2.37Charge transfer-oxy radical mechanism for anti-cancer agents. ( Ames, JR; Cox, O; Elo, H; Jackson, H; Kovacic, P; Lumme, P; Ramirez, L; Rivera, LA; Ryan, MD, 1986)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's4 (33.33)29.6817
2010's7 (58.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Willemann, C1
Grünert, R1
Bednarski, PJ1
Troschütz, R1
Queiroz, MJ1
Peixoto, D1
Calhelha, RC1
Soares, P1
Dos Santos, T1
Lima, RT1
Campos, JF1
Abreu, RM1
Ferreira, IC1
Vasconcelos, MH1
Ngo, QA1
Nguyen, le A1
Vo, NB1
Nguyen, TH2
Roussi, F1
Nguyen, VT1
Hongthong, S1
Meesin, J1
Pailee, P1
Soorukram, D1
Kongsaeree, P1
Prabpai, S1
Piyachaturawat, P1
Jariyawat, S1
Suksen, K1
Jaipetch, T1
Nuntasaen, N1
Reutrakul, V1
Kuhakarn, C1
Le-Nhat-Thuy, G1
Dinh, TV1
Pham-The, H1
Nguyen Quang, H1
Nguyen Thi, N1
Dang Thi, TA1
Hoang Thi, P1
Le Thi, TA1
Nguyen, HT1
Nguyen Thanh, P1
Le Duc, T1
Nguyen, TV1
Xu, Z1
Zhao, SJ1
Liu, Y1
Studenovský, M1
Sedláček, O1
Hrubý, M1
Pánek, J1
Ulbrich, K1
Prudent, R1
Moucadel, V1
Nguyen, CH1
Barette, C1
Schmidt, F1
Florent, JC1
Lafanechère, L1
Sautel, CF1
Duchemin-Pelletier, E1
Spreux, E1
Filhol, O1
Reiser, JB1
Cochet, C1
Garbett, NC1
Graves, DE1
Wang, W1
El-Deiry, WS1
Kovacic, P1
Ames, JR1
Lumme, P1
Elo, H1
Cox, O1
Jackson, H1
Rivera, LA1
Ramirez, L1
Ryan, MD1

Reviews

4 reviews available for ellipticine and Neoplasms

ArticleYear
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Tria

2019
Extending nature's leads: the anticancer agent ellipticine.
    Current medicinal chemistry. Anti-cancer agents, 2004, Volume: 4, Issue:2

    Topics: Animals; Antineoplastic Agents; Apocynaceae; Ellipticines; Humans; Neoplasms; Phytotherapy; Structur

2004
Restoration of p53 to limit tumor growth.
    Current opinion in oncology, 2008, Volume: 20, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle

2008
Charge transfer-oxy radical mechanism for anti-cancer agents.
    Anti-cancer drug design, 1986, Volume: 1, Issue:3

    Topics: Alkylation; Antineoplastic Agents; Antioxidants; DNA; Ellipticines; Free Radicals; Mercaptopurine; M

1986

Other Studies

8 other studies available for ellipticine and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Synthesis and cytotoxic activity of 5,6-heteroaromatically annulated pyridine-2,4-diamines.
    Bioorganic & medicinal chemistry, 2009, Jul-01, Volume: 17, Issue:13

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Diamines; Drug Screening Assays, Antitu

2009
New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death.
    European journal of medicinal chemistry, 2013, Volume: 69

    Topics: Amines; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line; Cell Proliferation; Dose-Response R

2013
Synthesis and antiproliferativeactivity of new vinca alkaloids containing an α,β-unsaturated aromatic side chain.
    Bioorganic & medicinal chemistry letters, 2015, Dec-01, Volume: 25, Issue:23

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Humans; Inhibitory Concentration 50; Molecular

2015
Cytotoxic lanostanes from fruits of Garcinia wallichii Choisy (Guttiferae).
    Bioorganic & medicinal chemistry letters, 2016, 12-01, Volume: 26, Issue:23

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Fruit; Garcinia; Humans; Lanosterol; Models, Mo

2016
Design, synthesis and evaluation of novel hybrids between 4-anilinoquinazolines and substituted triazoles as potent cytotoxic agents.
    Bioorganic & medicinal chemistry letters, 2018, 12-15, Volume: 28, Issue:23-24

    Topics: Amino Acid Sequence; Aniline Compounds; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug S

2018
Multi-responsive polymer micelles as ellipticine delivery carriers for cancer therapy.
    Anticancer research, 2015, Volume: 35, Issue:2

    Topics: Antineoplastic Agents; Ellipticines; Half-Life; Hydrogen-Ion Concentration; Micelles; Neoplasms; Pol

2015
Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2.
    Cancer research, 2010, Dec-01, Volume: 70, Issue:23

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carbazoles; Casei

2010