ellipticine has been researched along with Leukemia in 5 studies
ellipticine : A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ellipticine induces formation of two DNA adducts in leukemia HL-60 and CCRF-CEM cells, identical with deoxyguanosine adducts generated by ellipticine metabolites 13-hydroxyellipticine and 12-hydroxyellipticine in vitro and in vivo." | 7.74 | DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells. ( Aimová, D; Eckschlager, T; Frei, E; Gomez, JE; Hrabeta, J; Poljaková, J; Stiborová, M, 2007) |
| "Ellipticine induces formation of two DNA adducts in leukemia HL-60 and CCRF-CEM cells, identical with deoxyguanosine adducts generated by ellipticine metabolites 13-hydroxyellipticine and 12-hydroxyellipticine in vitro and in vivo." | 3.74 | DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells. ( Aimová, D; Eckschlager, T; Frei, E; Gomez, JE; Hrabeta, J; Poljaková, J; Stiborová, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Devraj, R | 1 |
| Barrett, JF | 1 |
| Fernandez, JA | 1 |
| Katzenellenbogen, JA | 1 |
| Cushman, M | 1 |
| Isaka, M | 1 |
| Jaturapat, A | 1 |
| Rukseree, K | 1 |
| Danwisetkanjana, K | 1 |
| Tanticharoen, M | 1 |
| Thebtaranonth, Y | 1 |
| Shahabuddin, MS | 1 |
| Nambiar, M | 1 |
| Moorthy, BT | 1 |
| Naik, PL | 1 |
| Choudhary, B | 1 |
| Advirao, GM | 1 |
| Raghavan, SC | 1 |
| Poljaková, J | 1 |
| Frei, E | 1 |
| Gomez, JE | 1 |
| Aimová, D | 1 |
| Eckschlager, T | 1 |
| Hrabeta, J | 1 |
| Stiborová, M | 1 |
| Shenoy, S | 1 |
| Vasania, VS | 1 |
| Gopal, M | 1 |
| Mehta, A | 1 |
5 other studies available for ellipticine and Leukemia
| Article | Year |
|---|---|
Design, synthesis, and biological evaluation of ellipticine-estradiol conjugates.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Survival; Central Nerv | 1996 |
Phomoxanthones A and B, novel xanthone dimers from the endophytic fungus Phomopsis species.
Topics: Animals; Antimalarials; Antineoplastic Agents; Antitubercular Agents; Ascomycota; Carcinoma, Squamou | 2001 |
A novel structural derivative of natural alkaloid ellipticine, MDPSQ, induces necrosis in leukemic cells.
Topics: Alkaloids; Annexin A5; Apoptosis; Biological Transport; Cell Cycle; Cell Death; Cell Line, Tumor; Ce | 2011 |
DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; DNA Adducts; Ellipticines; Humans; Leukemia | 2007 |
8-Methyl-4-(3-diethylaminopropylamino) pyrimido [4',5';4,5] thieno (2,3-b) quinoline (MDPTQ), a quinoline derivate that causes ROS-mediated apoptosis in leukemia cell lines.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; DNA Damage; E | 2007 |