ellipticine has been researched along with Leukemia L 1210 in 17 studies
ellipticine : A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dose-response curve was bell-shaped for both compounds." | 1.28 | Production of protein-associated DNA breaks by 8-methoxycaffeine, caffeine and 8-chlorocaffeine in isolated nuclei from L1210 cells: comparison with those produced by topoisomerase II inhibitors. ( Kohn, KW; Parodi, S; Pedrini, AM; Poggi, L; Pommier, Y; Russo, P, 1991) |
| "8-MOC has been postulated to produce chromosomal aberrations by DNA topoisomerase II inhibition." | 1.28 | 8-methoxycaffeine-induced protein-associated DNA breaks in isolated L1210 cell nuclei. ( Billi, G; Brega, I; Parodi, S; Piccini, D; Poggi, L; Russo, P; Vigani, A; Zignaigo, G, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (52.94) | 18.7374 |
| 1990's | 6 (35.29) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ruckdeschel, JC | 1 |
| Modi, SP | 1 |
| el-Hamouly, W | 1 |
| Portuese, E | 1 |
| Archer, S | 1 |
| Honda, T | 1 |
| Kato, M | 1 |
| Inoue, M | 1 |
| Shimamoto, T | 1 |
| Shima, K | 1 |
| Nakanishi, T | 1 |
| Yoshida, T | 1 |
| Noguchi, T | 1 |
| Werbel, LM | 1 |
| Angelo, M | 1 |
| Fry, DW | 1 |
| Worth, DF | 1 |
| Delbarre, A | 1 |
| Oberlin, R | 1 |
| Roques, BP | 1 |
| Borgna, JL | 1 |
| Rochefort, H | 1 |
| Le Pecq, JB | 1 |
| Jacquemin-Sablon, A | 1 |
| Tran-Thi, HA | 1 |
| Nguyen-Thi, T | 1 |
| Michel, S | 1 |
| Tillequin, F | 1 |
| Koch, M | 1 |
| Pfeiffer, B | 1 |
| Pierré, A | 3 |
| Trinh-Van-Dufat, H | 1 |
| Pommier, Y | 2 |
| Schwartz, RE | 1 |
| Kohn, KW | 2 |
| Zwelling, LA | 1 |
| Paoletti, C | 3 |
| Auclair, C | 2 |
| Lesca, P | 1 |
| Tocanne, JF | 1 |
| Malvy, C | 2 |
| Pinto, M | 1 |
| Moinet-Hedin, V | 1 |
| Tabka, T | 1 |
| Poulain, L | 1 |
| Godard, T | 1 |
| Lechevrel, M | 1 |
| Saturnino, C | 1 |
| Lancelot, JC | 1 |
| Le Talaër, JY | 1 |
| Gauduchon, P | 1 |
| Djuric, Z | 1 |
| Everett, CK | 1 |
| Valeriote, FA | 1 |
| Russo, P | 2 |
| Poggi, L | 2 |
| Parodi, S | 2 |
| Pedrini, AM | 1 |
| Monnot, M | 1 |
| Mauffret, O | 1 |
| Simon, V | 1 |
| Lescot, E | 1 |
| Psaume, B | 1 |
| Saucier, JM | 2 |
| Charra, M | 1 |
| Belehradek, J | 1 |
| Fermandjian, S | 1 |
| Zignaigo, G | 1 |
| Vigani, A | 1 |
| Billi, G | 1 |
| Brega, I | 1 |
| Piccini, D | 1 |
| Samadi-Baboli, M | 1 |
| Favre, G | 1 |
| Bernadou, J | 1 |
| Berg, D | 1 |
| Soula, G | 1 |
| Pierson, V | 1 |
| de Cointet, P | 1 |
| Nguyen, CH | 1 |
| Bisagni, E | 2 |
| Gros, P | 2 |
| Larue, L | 1 |
| Rivalle, C | 1 |
| Muzard, G | 1 |
| Paoletti, J | 1 |
| Voisin, E | 1 |
| Pepin, O | 1 |
| Cros, S | 2 |
| Colas, C | 1 |
| Verschuere, B | 1 |
1 review available for ellipticine and Leukemia L 1210
| Article | Year |
|---|---|
Ellipticine, 9-hydroxyellipticine, and 9-hydroxyellipiticinum: some biochemical properties of possible pharmacologic significance.
Topics: Alkaloids; Animals; Cytochrome P-450 Enzyme System; DNA; Ellipticines; Leukemia L1210; Membrane Lipi | 1981 |
16 other studies available for ellipticine and Leukemia L 1210
| Article | Year |
|---|---|
N-methylcarbamate derivatives of ellipticine and olivacine with cytotoxic activity against four human lung cancer cell lines.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carbamates; Ellipticines; Humans; Leukemia L1210; Lung N | 1992 |
Synthesis and antitumor activity of quaternary ellipticine glycosides, a series of novel and highly active antitumor agents.
Topics: Alkaloids; Animals; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; Ellipticines; Glycoside | 1988 |
Basically substituted ellipticine analogues as potential antitumor agents.
Topics: Alkaloids; Animals; Drug Evaluation, Preclinical; Ellipticines; Indicators and Reagents; Leukemia L1 | 1986 |
Ellipticine derivatives with an affinity to the estrogen receptor, an approach to develop intercalating drugs with a specific effect on the hormone-dependent breast cancer.
Topics: Alkaloids; Animals; Breast Neoplasms; Cattle; Cell Line; DNA; Ellipticines; Female; Humans; In Vitro | 1985 |
Synthesis and cytotoxic activity of pyranocarbazole analogues of ellipticine and acronycine.
Topics: Acronine; Animals; Antineoplastic Agents; Carbazoles; Cell Line, Tumor; Ellipticines; Leukemia L1210 | 2004 |
Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents.
Topics: Adenosine Triphosphate; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Binding Sites; Da | 1984 |
Biological properties of 5,11-dimethyl-6H-pyrido[3,2-b]carbazoles: a new class of potent antitumour drugs.
Topics: Animals; Antineoplastic Agents; Cell Survival; Comet Assay; DNA Damage; Drug Design; Ellipticines; L | 2000 |
DNA damage and cytotoxicity in L1210 cells by ellipticine and a structural analogue, N-2-(diethylaminoethyl)-9-hydroxyellipticinium chloride.
Topics: Animals; DNA Damage; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Drug Screening Assays, Antitum | 1992 |
Production of protein-associated DNA breaks by 8-methoxycaffeine, caffeine and 8-chlorocaffeine in isolated nuclei from L1210 cells: comparison with those produced by topoisomerase II inhibitors.
Topics: Animals; Autoradiography; Caffeine; Cell Nucleus; DNA Damage; DNA Topoisomerases, Type II; DNA-Bindi | 1991 |
DNA-drug recognition and effects on topoisomerase II-mediated cytotoxicity. A three-mode binding model for ellipticine derivatives.
Topics: Animals; Cell Survival; Circular Dichroism; DNA; DNA Damage; DNA Topoisomerases, Type II; Ellipticin | 1991 |
8-methoxycaffeine-induced protein-associated DNA breaks in isolated L1210 cell nuclei.
Topics: Animals; Caffeine; Chromosome Aberrations; Cross-Linking Reagents; DNA Damage; Doxorubicin; Elliptic | 1990 |
Comparative study of the incorporation of ellipticine-esters into low density lipoprotein (LDL) and selective cell uptake of drug--LDL complex via the LDL receptor pathway in vitro.
Topics: Alkaloids; Animals; Cell Survival; Ellipticines; Leukemia L1210; Lipoproteins, LDL; Macrophages; Rec | 1990 |
Interrelationship between affinity for DNA, cytotoxicity and induction of DNA-breaks in cultured L1210 cells for two series of tricyclic intercalators. Simplified analogues of ellipticine derivatives.
Topics: Alkaloids; Amsacrine; Animals; Cell Survival; DNA; DNA Damage; DNA, Neoplasm; Ellipticines; Intercal | 1989 |
A new series of ellipticine derivatives (1-(alkylamino)-9-methoxyellipticine). Synthesis, DNA binding, and biological properties.
Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Line; Cell Survival; DNA; Ellipticines; Intercalatin | 1988 |
Physicochemical and pharmacological properties of the antitumor ellipticine derivative 2-(diethylamino-2-ethyl)9-hydroxy ellipticinium-chloride, HCl.
Topics: Adenocarcinoma; Alkaloids; Animals; Antineoplastic Agents; Cell Line; Chemical Phenomena; Chemistry, | 1987 |
Interaction between ellipticine derivatives and circular supercoiled DNA as revealed by gel electrophoresis. Possible relationship with the mechanisms of cytotoxicity .
Topics: Alkaloids; Animals; Cell Survival; Cells, Cultured; DNA, Superhelical; Electrophoresis, Agar Gel; El | 1986 |