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ellipticine and Cancer of Lung

ellipticine has been researched along with Cancer of Lung in 13 studies

ellipticine : A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.

Research Excerpts

ExcerptRelevanceReference
"The carbazole scaffold is an active structure showing anti-cancer biological activity, and the structural diversity has been expanded through the improvement and optimization of synthesizing methods."5.72Design, synthesis, and evaluation of 9-(pyrimidin-2-yl)-9H-carbazole derivatives disrupting mitochondrial homeostasis in human lung adenocarcinoma. ( Chen, YR; Li, KT; Ou, TM; Su, XX; Sun, JW; Wang, H; Wang, XN; Wu, JQ; Wu, XZ, 2022)
"The carbazole scaffold is an active structure showing anti-cancer biological activity, and the structural diversity has been expanded through the improvement and optimization of synthesizing methods."1.72Design, synthesis, and evaluation of 9-(pyrimidin-2-yl)-9H-carbazole derivatives disrupting mitochondrial homeostasis in human lung adenocarcinoma. ( Chen, YR; Li, KT; Ou, TM; Su, XX; Sun, JW; Wang, H; Wang, XN; Wu, JQ; Wu, XZ, 2022)
" This drug delivery system offers exciting possibilities for cancer therapy by increasing the bioavailability of anti-neoplastic drug to the tumor site."1.39Synthesis of poly-(3-hydroxybutyrate-co-12 mol % 3-hydroxyvalerate) by Bacillus cereus FB11: its characterization and application as a drug carrier. ( Ahmad, B; Chen, P; Hameed, A; Hasan, F; Masood, F; Yasin, T, 2013)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's2 (15.38)18.2507
2000's3 (23.08)29.6817
2010's5 (38.46)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Ruckdeschel, JC1
Modi, SP1
el-Hamouly, W1
Portuese, E1
Archer, S1
Devraj, R1
Barrett, JF1
Fernandez, JA1
Katzenellenbogen, JA1
Cushman, M1
Scio, E1
Ribeiro, A1
Alves, TM1
Romanha, AJ1
Shin, YG1
Cordell, GA1
Zani, CL1
Toviwek, B1
Suphakun, P1
Choowongkomon, K1
Hannongbua, S1
Gleeson, MP1
Su, XX1
Chen, YR1
Wu, JQ1
Wu, XZ1
Li, KT1
Wang, XN1
Sun, JW1
Wang, H1
Ou, TM1
Gębarowski, T1
Wiatrak, B1
Gębczak, K1
Tylińska, B1
Gąsiorowski, K1
Masood, F1
Chen, P3
Yasin, T1
Hasan, F1
Ahmad, B1
Hameed, A1
Wang, JP1
Yu, YC1
Chen, SP2
Liang, HC1
Lin, CW2
Fang, K2
Zhang, L1
Bennett, WF1
Zheng, T1
Ouyang, PK1
Ouyang, X1
Qiu, X1
Luo, A1
Karttunen, M1
Cheng, WC1
Huang, HT1
Wu, Y1
Sadatmousavi, P1
Wang, R1
Lu, S1
Yuan, YF1
Moody, TW1
Czerwinski, G1
Tarasova, NI1
Moody, DL1
Michejda, CJ1
Keizer, HG1
De Leeuw, SJ1
Van Rijn, J1
Pinedo, HM1
Joenje, H1

Other Studies

13 other studies available for ellipticine and Cancer of Lung

ArticleYear
N-methylcarbamate derivatives of ellipticine and olivacine with cytotoxic activity against four human lung cancer cell lines.
    Journal of medicinal chemistry, 1992, Dec-25, Volume: 35, Issue:26

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carbamates; Ellipticines; Humans; Leukemia L1210; Lung N

1992
Design, synthesis, and biological evaluation of ellipticine-estradiol conjugates.
    Journal of medicinal chemistry, 1996, Aug-16, Volume: 39, Issue:17

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Survival; Central Nerv

1996
New bioactive coumarins from Kielmeyera albopunctata.
    Journal of natural products, 2003, Volume: 66, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Brazil; Chagas Disease; Clusiaceae; Coumarins; Humans; K

2003
Synthesis and evaluation of the NSCLC anti-cancer activity and physical properties of 4-aryl-N-phenylpyrimidin-2-amines.
    Bioorganic & medicinal chemistry letters, 2017, 10-15, Volume: 27, Issue:20

    Topics: A549 Cells; Amines; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Pr

2017
Design, synthesis, and evaluation of 9-(pyrimidin-2-yl)-9H-carbazole derivatives disrupting mitochondrial homeostasis in human lung adenocarcinoma.
    European journal of medicinal chemistry, 2022, Mar-15, Volume: 232

    Topics: Adenocarcinoma of Lung; Animals; Carbazoles; Carcinoma, Non-Small-Cell Lung; Homeostasis; Humans; Lu

2022
Effect of new olivacine derivatives on p53 protein level.
    Pharmacological reports : PR, 2020, Volume: 72, Issue:1

    Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; BALB 3T3 Cells; Cell Line, Tumor; Ellipticine

2020
Synthesis of poly-(3-hydroxybutyrate-co-12 mol % 3-hydroxyvalerate) by Bacillus cereus FB11: its characterization and application as a drug carrier.
    Journal of materials science. Materials in medicine, 2013, Volume: 24, Issue:8

    Topics: Antineoplastic Agents; Bacillus cereus; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Carri

2013
The collective nuclear migration of p53 and phosphorylated S473 of Akt during ellipticine-mediated apoptosis in human lung epithelial cancer cells.
    Molecular and cellular biochemistry, 2015, Volume: 407, Issue:1-2

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Nucleus; Cell Survival; Ellipticines; Gene

2015
Effect of Cholesterol on Cellular Uptake of Cancer Drugs Pirarubicin and Ellipticine.
    The journal of physical chemistry. B, 2016, Mar-31, Volume: 120, Issue:12

    Topics: Animals; Antineoplastic Agents; Cell Membrane; Cells, Cultured; CHO Cells; Cholesterol; Cricetulus;

2016
Ellipticine-induced apoptosis depends on Akt translocation and signaling in lung epithelial cancer cells.
    Lung cancer (Amsterdam, Netherlands), 2009, Volume: 63, Issue:2

    Topics: Active Transport, Cell Nucleus; Androstadienes; Antineoplastic Agents; Apoptosis; Autophagy; Cell Cy

2009
Self-assembling peptide-based nanoparticles enhance anticancer effect of ellipticine in vitro and in vivo.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Dr

2012
The development of VIP-ellipticine conjugates.
    Regulatory peptides, 2004, Dec-15, Volume: 123, Issue:1-3

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Drug Design; Ellipticines;

2004
Effect of artificial electron acceptors on the cytotoxicity of mitomycin C and doxorubicin in human lung tumor cells.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:7

    Topics: Carcinoma, Squamous Cell; Doxorubicin; Drug Interactions; Ellipticines; Humans; Lung Neoplasms; Meth

1989