Page last updated: 2024-10-26

ellipticine and Cancer of Colon

ellipticine has been researched along with Cancer of Colon in 5 studies

ellipticine : A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.

Research Excerpts

ExcerptRelevanceReference
" With this image-based assay, we identified ellipticine that increased the nuclear localization of GFP-mutant p53 protein but not GFP alone in Saos-2 osteosarcoma cells."3.74A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization. ( Datti, A; Dennis, JW; Koch, CA; Macrae, CJ; Mawji, IA; Schimmer, AD; Wrana, JL; Xu, GW, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lu, C1
Wang, W2
El-Deiry, WS2
Huang, C1
Zhang, XM1
Tavaluc, RT1
Hart, LS1
Dicker, DT1
Xu, GW1
Mawji, IA1
Macrae, CJ1
Koch, CA1
Datti, A1
Wrana, JL1
Dennis, JW1
Schimmer, AD1
Ohashi, M1
Sugikawa, E1
Nakanishi, N1
Auclair, C1
Pierre, A1
Voisin, E1
Pepin, O1
Cros, S1
Colas, C1
Saucier, JM1
Verschuere, B1
Gros, P1
Paoletti, C1

Other Studies

5 other studies available for ellipticine and Cancer of Colon

ArticleYear
Non-genotoxic anti-neoplastic effects of ellipticine derivative NSC176327 in p53-deficient human colon carcinoma cells involve stimulation of p73.
    Cancer biology & therapy, 2008, Volume: 7, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Survival; Colonic Neoplasms; DNA-Binding Proteins

2008
The combination of 5-fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells.
    Cancer biology & therapy, 2009, Volume: 8, Issue:22

    Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; DNA-Binding Proteins; Drug Synergism; Elli

2009
A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization.
    Apoptosis : an international journal on programmed cell death, 2008, Volume: 13, Issue:3

    Topics: Active Transport, Cell Nucleus; Cell Line, Tumor; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibit

2008
Inhibition of p53 protein phosphorylation by 9-hydroxyellipticine: a possible anticancer mechanism.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Lewis Lung; CDC2-CDC28 Kinases; Cell

1995
Physicochemical and pharmacological properties of the antitumor ellipticine derivative 2-(diethylamino-2-ethyl)9-hydroxy ellipticinium-chloride, HCl.
    Cancer research, 1987, Dec-01, Volume: 47, Issue:23

    Topics: Adenocarcinoma; Alkaloids; Animals; Antineoplastic Agents; Cell Line; Chemical Phenomena; Chemistry,

1987