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ellipticine and Breast Cancer

ellipticine has been researched along with Breast Cancer in 16 studies

ellipticine : A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.

Research Excerpts

ExcerptRelevanceReference
"The effects of vasoactive intestinal peptide (VIP)-ellipticine (E) derivatives were investigated on breast cancer cells."7.71VIP-ellipticine derivatives inhibit the growth of breast cancer cells. ( Czerwinski, G; Michejda, CJ; Moody, TW; Tarasova, NI, 2002)
"Targeting breast cancer stem cells (BCSCs) offers a promising strategy for breast cancer treatment."5.40Effects of ellipticine on ALDH1A1-expressing breast cancer stem cells--an in vitro and in silico study. ( Banarji, A; Chauhan, PS; Chikati, R; Kumar, CS; Pandrangi, SL; Saxena, S, 2014)
"The effects of vasoactive intestinal peptide (VIP)-ellipticine (E) derivatives were investigated on breast cancer cells."3.71VIP-ellipticine derivatives inhibit the growth of breast cancer cells. ( Czerwinski, G; Michejda, CJ; Moody, TW; Tarasova, NI, 2002)
"Targeting breast cancer stem cells (BCSCs) offers a promising strategy for breast cancer treatment."1.40Effects of ellipticine on ALDH1A1-expressing breast cancer stem cells--an in vitro and in silico study. ( Banarji, A; Chauhan, PS; Chikati, R; Kumar, CS; Pandrangi, SL; Saxena, S, 2014)
"Ellipticine treatment increased the expression of Fas/APO-1 and its ligands, mFas ligand and sFas ligand, and subsequent activation of caspase-8."1.33The mechanism of ellipticine-induced apoptosis and cell cycle arrest in human breast MCF-7 cancer cells. ( Chang, CH; Hsu, YL; Kuo, PL; Lin, CC, 2005)
"Ellipticine treatment arrested MDA-MB-231 cells at the G2/M phase after 6 h of treatment."1.33The anti-proliferative inhibition of ellipticine in human breast mda-mb-231 cancer cells is through cell cycle arrest and apoptosis induction. ( Chang, CH; Hsu, YL; Kuo, PL; Kuo, YC; Lin, CC, 2005)
"MCF-7 human breast cancer cells, selected for resistance to adriamycin (AdrR), exhibit the phenotype of multidrug resistance (MDR)."1.27Altered regulation of P-450IA1 expression in a multidrug-resistant MCF-7 human breast cancer cell line. ( Averbuch, SD; Baird, WM; Cowan, KH; Fairchild, CR; Ivy, SP; Myers, CE; Nebert, DW; Tulpule, A, 1988)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's2 (12.50)18.2507
2000's3 (18.75)29.6817
2010's7 (43.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Delbarre, A1
Oberlin, R1
Roques, BP1
Borgna, JL1
Rochefort, H1
Le Pecq, JB1
Jacquemin-Sablon, A1
Devraj, R1
Barrett, JF1
Fernandez, JA1
Katzenellenbogen, JA1
Cushman, M1
Al-Trawneh, SA2
Zahra, JA2
Kamal, MR1
El-Abadelah, MM2
Zani, F2
Incerti, M2
Cavazzoni, A2
Alfieri, RR1
Petronini, PG1
Vicini, P2
Al-Taweel, SA1
Rizza, P1
Pellegrino, M1
Caruso, A2
Iacopetta, D2
Sinicropi, MS2
Rault, S2
Lancelot, JC1
El-Kashef, H2
Lesnard, A1
Rochais, C1
Dallemagne, P2
Saturnino, C2
Giordano, F1
Catalano, S1
Andò, S1
Ceramella, J1
Occhiuzzi, MA1
Barbarossa, A1
Rizzuti, B1
Grande, F1
Ghosh, S1
Kar, A1
Chowdhury, S1
Dasgupta, D1
Pandrangi, SL1
Chikati, R1
Chauhan, PS1
Kumar, CS1
Banarji, A1
Saxena, S1
Sedlacek, O1
Kucka, J1
Mattova, J1
Parizek, M1
Studenovsky, M1
Zadinova, M1
Pouckova, P1
Hruby, M1
Kuo, PL2
Hsu, YL2
Chang, CH2
Lin, CC2
Kuo, YC1
Oster, JB1
Creasey, WA1
Sureau, F1
Moreau, F1
Millot, JM1
Manfait, M1
Allard, B1
Aubard, J1
Schwaller, MA1
Moody, TW1
Czerwinski, G1
Tarasova, NI1
Michejda, CJ1
Vickers, PJ1
Dufresne, MJ1
Cowan, KH2
Ivy, SP1
Tulpule, A1
Fairchild, CR1
Averbuch, SD1
Myers, CE1
Nebert, DW1
Baird, WM1

Other Studies

16 other studies available for ellipticine and Breast Cancer

ArticleYear
Ellipticine derivatives with an affinity to the estrogen receptor, an approach to develop intercalating drugs with a specific effect on the hormone-dependent breast cancer.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:6

    Topics: Alkaloids; Animals; Breast Neoplasms; Cattle; Cell Line; DNA; Ellipticines; Female; Humans; In Vitro

1985
Design, synthesis, and biological evaluation of ellipticine-estradiol conjugates.
    Journal of medicinal chemistry, 1996, Aug-16, Volume: 39, Issue:17

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Survival; Central Nerv

1996
Synthesis and biological evaluation of tetracyclic fluoroquinolones as antibacterial and anticancer agents.
    Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell

2010
Synthesis and biological evaluation of tetracyclic thienopyridones as antibacterial and antitumor agents.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell

2011
3-(Dipropylamino)-5-hydroxybenzofuro[2,3-f]quinazolin-1(2H)-one (DPA-HBFQ-1) plays an inhibitory role on breast cancer cell growth and progression.
    European journal of medicinal chemistry, 2016, Jan-01, Volume: 107

    Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Breast Neoplasms; Cell Line, Tumor; Chemistry Techniq

2016
Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization.
    European journal of medicinal chemistry, 2019, Nov-01, Volume: 181

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; DNA Topoisomerases, Type I; Drug Design;

2019
Ellipticine binds to a human telomere sequence: an additional mode of action as a putative anticancer agent?
    Biochemistry, 2013, Jun-18, Volume: 52, Issue:24

    Topics: Antineoplastic Agents; Breast Neoplasms; Calorimetry, Differential Scanning; Cell Line, Tumor; Circu

2013
Effects of ellipticine on ALDH1A1-expressing breast cancer stem cells--an in vitro and in silico study.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:1

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Amino Acid Sequence; Antineoplastic Agents;

2014
Multistage-targeted pH-responsive polymer conjugate of Auger electron emitter: optimized design and in vivo activity.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Oct-15, Volume: 63

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Drug Delivery Systems; Drug Screening Assays, Anti

2014
The mechanism of ellipticine-induced apoptosis and cell cycle arrest in human breast MCF-7 cancer cells.
    Cancer letters, 2005, Jun-08, Volume: 223, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carrier Proteins; Cell Cycle; Cell Proliferation

2005
The anti-proliferative inhibition of ellipticine in human breast mda-mb-231 cancer cells is through cell cycle arrest and apoptosis induction.
    Anti-cancer drugs, 2005, Volume: 16, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell P

2005
Enhancement of cellular uptake of ellipticine by insulin preincubation.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:10

    Topics: Alkaloids; Animals; Breast Neoplasms; Cell Survival; Cells, Cultured; DNA; Dose-Response Relationshi

1981
Microspectrofluorometry of the protonation state of ellipticine, an antitumor alkaloid, in single cells.
    Biophysical journal, 1993, Volume: 65, Issue:5

    Topics: Biophysical Phenomena; Biophysics; Breast Neoplasms; Chromatin; DNA, Neoplasm; Ellipticines; Female;

1993
VIP-ellipticine derivatives inhibit the growth of breast cancer cells.
    Life sciences, 2002, Jul-19, Volume: 71, Issue:9

    Topics: Amino Acid Sequence; Breast Neoplasms; Cell Division; Ellipticines; Humans; Molecular Sequence Data;

2002
Relation between cytochrome P450IA1 expression and estrogen receptor content of human breast cancer cells.
    Molecular endocrinology (Baltimore, Md.), 1989, Volume: 3, Issue:1

    Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Breast Neoplasms; Cell Nucleus; Cytochrome P-450 Enzy

1989
Altered regulation of P-450IA1 expression in a multidrug-resistant MCF-7 human breast cancer cell line.
    The Journal of biological chemistry, 1988, Dec-15, Volume: 263, Issue:35

    Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Blotting, Northern; Breast Neoplasms; Cell Line; Chlo

1988