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ellipticine and Brain Neoplasms

ellipticine has been researched along with Brain Neoplasms in 4 studies

ellipticine : A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
"The cytotoxicity of ellipticine to neuroblastomas was increased by pre-treating these cells with VPA or TSA."7.77Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma. ( Dvorakova, M; Eckschlager, T; Frei, E; Göttlicherova, M; Hrabeta, J; Hrebackova, J; Kizek, R; Kopejtkova, B; Moserova, M; Poljakova, J; Stiborova, M, 2011)
"The cytotoxicity of ellipticine to neuroblastomas was increased by pre-treating these cells with VPA or TSA."3.77Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma. ( Dvorakova, M; Eckschlager, T; Frei, E; Göttlicherova, M; Hrabeta, J; Hrebackova, J; Kizek, R; Kopejtkova, B; Moserova, M; Poljakova, J; Stiborova, M, 2011)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Acton, EM1
Narayanan, VL1
Risbood, PA1
Shoemaker, RH1
Vistica, DT1
Boyd, MR1
Jurayj, J1
Haugwitz, RD1
Varma, RK1
Paull, KD1
Barrett, JF1
Cushman, M1
Banerjee, S1
Pabbathi, A1
Sekhar, MC1
Samanta, A1
Poljakova, J1
Hrebackova, J1
Dvorakova, M1
Moserova, M1
Eckschlager, T1
Hrabeta, J1
Göttlicherova, M1
Kopejtkova, B1
Frei, E1
Kizek, R1
Stiborova, M1

Other Studies

4 other studies available for ellipticine and Brain Neoplasms

ArticleYear
Anticancer specificity of some ellipticinium salts against human brain tumors in vitro.
    Journal of medicinal chemistry, 1994, Jul-08, Volume: 37, Issue:14

    Topics: Brain Neoplasms; Drug Evaluation, Preclinical; Ellipticines; Humans; Structure-Activity Relationship

1994
Design and synthesis of ellipticinium salts and 1,2-dihydroellipticines with high selectivities against human CNS cancers in vitro.
    Journal of medicinal chemistry, 1994, Jul-08, Volume: 37, Issue:14

    Topics: Brain Neoplasms; Drug Design; Drug Evaluation, Preclinical; Ellipticines; Humans; Structure-Activity

1994
Dual fluorescence of ellipticine: excited state proton transfer from solvent versus solvent mediated intramolecular proton transfer.
    The journal of physical chemistry. A, 2011, Aug-25, Volume: 115, Issue:33

    Topics: Antineoplastic Agents; Brain Neoplasms; Ellipticines; Fluorescence; Humans; Hydrogen Bonding; Hydrop

2011
Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma.
    Neuro endocrinology letters, 2011, Volume: 32 Suppl 1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; DNA Damage; Dose-Response

2011