elastin and Toxoplasmosis

elastin has been researched along with Toxoplasmosis* in 1 studies

Other Studies

1 other study(ies) available for elastin and Toxoplasmosis

ArticleYear
Elevated concentrations of matrix metalloproteinase-12 and elastin degradation products in the sera of pregnant women infected with Toxoplasma gondii.
    Annals of tropical medicine and parasitology, 2011, Volume: 105, Issue:3

    Although the expression of matrix metalloproteinase-12 (MMP-12) appears to be increased in most inflammatory diseases, the role of this enzyme in the pathogenesis of toxoplasmosis in pregnant women, if any, is unknown. In a recent study in Taiwan, the serum concentrations of MMP-12 and its substrate elastin were evaluated in pregnant women with Toxoplasma gondii infection. Compared with the healthy pregnant and non-pregnant women used as controls, the pregnant women with toxoplasmosis had significantly higher serum concentrations of MMP-12 and significantly higher levels of elastin synthesis and degradation. Interaction between MMP-12 and elastin in the serum samples was confirmed by co-immunoprecipitation. It seems possible that MMP-12 may contribute to elastin degradation occurring during the pathogenesis of toxoplasmosis in pregnant women.

    Topics: Antibodies, Protozoan; Elastin; Female; Humans; Immunoglobulin G; Immunoglobulin M; Matrix Metalloproteinase 12; Pregnancy; Pregnancy Complications, Parasitic; Toxoplasma; Toxoplasmosis

2011