elastin and Precancerous-Conditions

Chemical peeling is a common treatment in cosmetic dermatology. A peel that has been used for many years is trichloroacetic acid. Its adverse effects have for a long time been a major limitation. We present a practical review of the characteristics, mechanisms of action, indications, and complications of superficial chemical peels and of peeling with trichloroacetic acid.

Topics: Acids; Animals; Chemexfoliation; Collagen Type I; Drug Combinations; Elastin; Epidermis; Ethanol; Facial Dermatoses; Humans; Hyperpigmentation; Keratolytic Agents; Lactic Acid; Mice; Pigmentation Disorders; Precancerous Conditions; Resorcinols; Salicylates; Skin Aging; Skin Neoplasms; Trichloroacetic Acid

Topics: Animals; Basement Membrane; Cathepsin B; Cathepsins; Collagen; Connective Tissue; Elastin; Fibronectins; Glycosaminoglycans; Humans; Mast Cells; Microbial Collagenase; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Plasminogen Activators; Precancerous Conditions

Topics: Elastin; Endoscopy; Humans; Microscopy, Confocal; Precancerous Conditions; Prospective Studies; Pulmonary Alveoli; Reproducibility of Results; Respiratory Tract Neoplasms

A fibroproliferative lesion arising anterior to the lower end of the scapula and containing polymorphic often fiberlike deposits of weakly elastinophilic fibrillary material is described. It is compared on the light and ultrastructural level to a typical elastofibroma. The fibrillary material seen in this tumor strongly resembles that which surrounds the strongly elastinophilic deposits in the typical elastofibroma and from which the elastin is thought to be derived. It is concluded that elastin-producing tumors form a continuum; at one end of which lies the tumor we have designated pre-elastofibroma and at the other, the typical elastofibroma.

Topics: Bone Neoplasms; Elastin; Female; Fibroma; Humans; Middle Aged; Precancerous Conditions; Scapula