elastin and Leishmaniasis--Cutaneous

elastin has been researched along with Leishmaniasis--Cutaneous* in 1 studies

Other Studies

1 other study(ies) available for elastin and Leishmaniasis--Cutaneous

Article	Year
Matrix remodelling and fibroblast phenotype in early lesions of human cutaneous leishmaniasis. Pathology, research and practice, 1991, Volume: 187, Issue:8 The connective matrix participates directly in early pathological events observed in the cutaneous lesion of leishmaniasis, due to Leishmania braziliensis guyanensis. A sample of 19 skin biopsies was examined by light and electron microscopy, in order to identify the matrix components (collagen isotypes I to IV, elastin and membrane associated proteins) of the dermal infiltrate, and the pattern of organization of the reparative connective matrix. An extensive remodelling process of apparently parasite-independent nature involves different fibroblast sub-populations. The original organization of this immune-mediated lesion offers a rare opportunity to study in situ the local inflammatory mediators inducing the activation of fibroblasts and macrophages. Topics: Adolescent; Adult; Animals; Biopsy; Collagen; Connective Tissue; Elastin; Extracellular Matrix; Fibroblasts; Fluorescent Antibody Technique; Granuloma; Host-Parasite Interactions; Humans; Leishmaniasis, Cutaneous; Male; Membrane Proteins; Microscopy, Electron; Phenotype	1991

Article

Year

Matrix remodelling and fibroblast phenotype in early lesions of human cutaneous leishmaniasis.

Pathology, research and practice, 1991, Volume: 187, Issue:8

The connective matrix participates directly in early pathological events observed in the cutaneous lesion of leishmaniasis, due to Leishmania braziliensis guyanensis. A sample of 19 skin biopsies was examined by light and electron microscopy, in order to identify the matrix components (collagen isotypes I to IV, elastin and membrane associated proteins) of the dermal infiltrate, and the pattern of organization of the reparative connective matrix. An extensive remodelling process of apparently parasite-independent nature involves different fibroblast sub-populations. The original organization of this immune-mediated lesion offers a rare opportunity to study in situ the local inflammatory mediators inducing the activation of fibroblasts and macrophages.

Topics: Adolescent; Adult; Animals; Biopsy; Collagen; Connective Tissue; Elastin; Extracellular Matrix; Fibroblasts; Fluorescent Antibody Technique; Granuloma; Host-Parasite Interactions; Humans; Leishmaniasis, Cutaneous; Male; Membrane Proteins; Microscopy, Electron; Phenotype

1991