elafin and Carcinoma--Squamous-Cell

elafin has been researched along with Carcinoma--Squamous-Cell* in 2 studies

Other Studies

2 other study(ies) available for elafin and Carcinoma--Squamous-Cell

ArticleYear
Human Papillomavirus Regulates HER3 Expression in Head and Neck Cancer: Implications for Targeted HER3 Therapy in HPV
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2017, Jun-15, Volume: 23, Issue:12

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Elafin; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Head and Neck Neoplasms; Human papillomavirus 16; Humans; Mice; Molecular Targeted Therapy; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Papillomavirus Infections; Receptor, ErbB-3; Repressor Proteins; RNA, Small Interfering; Squamous Cell Carcinoma of Head and Neck; Xenograft Model Antitumor Assays

2017
Exploiting the head and neck cancer oncogenome: widespread PI3K-mTOR pathway alterations and novel molecular targets.
    Cancer discovery, 2013, Volume: 3, Issue:7

    Two studies published in this issue of Cancer Discovery describe the emerging mutational landscape of head and neck squamous cell carcinomas (HNSCC) and their genomic and epigenetic alterations, thus identifying novel actionable cancer drivers and predictive biomarkers for targeted therapies. Most genomic alterations in HNSCC converge in a handful of molecular pathways, resulting in cell-cycle deregulation, genomic instability, cell differentiation defects, and persistent mitogenic signaling, the latter involving aberrant phosphoinositide 3-kinase (PI3K)/mTOR pathway activation, thereby rendering HNSCC responsive to PI3K/mTOR inhibitors. Cancer Discov; 3(7); 722-5. ©2013 AACR.

    Topics: Carcinoma, Squamous Cell; Cell Cycle; Elafin; Gene Expression Regulation, Neoplastic; Genomic Instability; Head and Neck Neoplasms; Humans; Molecular Targeted Therapy; Protein Kinase Inhibitors; Signal Transduction; TOR Serine-Threonine Kinases

2013