elacridar has been researched along with Disease Models, Animal in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Crish, JF; Elmquist, WF; Gampa, G; Hinojosa, AQ; Kenchappa, RS; Kim, M; Luu, A; Mohammad, AS; Parrish, KE; Rosenfeld, SS; Sarkaria, JN; West, R | 1 |
| Abdallah, IM; Al-Shami, KM; Kaddoumi, A; Yang, E | 1 |
| Abreu, MT; Beck, AP; Cao, W; Chen, ML; Cominelli, F; Crynen, G; Delmas, A; Hommes, DW; Izard, T; Jackson, CB; Kayama, H; Kim, SY; Koralov, SB; Lacey, PN; Lorenz, RG; Martinez, GJ; McKevitt, K; Oikonomopoulos, A; Rangarajan, ES; Rodriguez-Palacios, A; Sun, A; Sundrud, MS; Takeda, K | 1 |
| Becher, OJ; Chung, AH; Crabtree, D; Elmquist, WF; Halvorson, KG; Hu, G; Mittapalli, RK; Parrish, KE | 1 |
| Bankstahl, JP; Bankstahl, M; Erker, T; Kuntner, C; Langer, O; Löscher, W; Mairinger, S; Müller, M; Sauberer, M; Stanek, J; Strommer, S; Wacheck, V; Wanek, T | 1 |
| Agarwal, S; Decker, SA; Donelson, R; Elmquist, WF; Gallardo, JL; Mittapalli, RK; Ohlfest, JR; Pokorny, JL; Santacruz, KS; Sarkaria, JN; Seiler, C; Zellmer, DM | 1 |
7 other study(ies) available for elacridar and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Benzamides; Blood-Brain Barrier; Brain; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Glioblastoma; Humans; Kinesins; Mice; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Proteins; Quinazolines; Tetrahydroisoquinolines; Xenograft Model Antitumor Assays | 2020 |
Blood-Brain Barrier Disruption Increases Amyloid-Related Pathology in TgSwDI Mice.
Topics: Acridines; Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Blood-Brain Barrier; Brain; Cell Line; Disease Models, Animal; Immunoglobulin G; Immunohistochemistry; Male; Matrix Metalloproteinase 9; Mice; Mice, Transgenic; NF-kappa B; Signal Transduction; Synapses; Tetrahydroisoquinolines; Tight Junctions | 2021 |
The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids.
Topics: Acridines; Adult; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Acids and Salts; Biological Transport; CD4-Positive T-Lymphocytes; Crohn Disease; Disease Models, Animal; Female; Gene Expression Regulation; Homeodomain Proteins; Homeostasis; Humans; Ileitis; Ileum; Immunity, Mucosal; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Oxidative Stress; Signal Transduction; Tetrahydroisoquinolines | 2017 |
ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B-Driven Brainstem Glioma Model.
Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Blood-Brain Barrier; Brain Stem Neoplasms; Cell Line, Tumor; Dasatinib; Disease Models, Animal; Drug Synergism; Gene Expression; Glioma; Humans; Mice; Mice, Knockout; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Tetrahydroisoquinolines; Treatment Outcome; Xenograft Model Antitumor Assays | 2016 |
A comparative small-animal PET evaluation of [11C]tariquidar, [11C]elacridar and (R)-[11C]verapamil for detection of P-glycoprotein-expressing murine breast cancer.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Breast Neoplasms; Carbon Radioisotopes; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Resistance, Neoplasm; Feasibility Studies; Female; Gene Expression Regulation, Neoplastic; Mice; Phenotype; Positron-Emission Tomography; Quinolines; Tetrahydroisoquinolines; Verapamil | 2012 |
Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Dasatinib; Disease Models, Animal; Endothelium, Vascular; Glioblastoma; Humans; Mice; Mice, Knockout; Molecular Targeted Therapy; Oncogenes; Permeability; Pyrimidines; Signal Transduction; Survival Analysis; Tetrahydroisoquinolines; Thiazoles; Tight Junctions; Tissue Distribution; Treatment Outcome; Xenograft Model Antitumor Assays | 2012 |