elacridar has been researched along with Breast Neoplasms in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmed-Belkacem, A; Blanc, M; Boumendjel, A; Di Pietro, A; Macalou, S | 1 |
| Azzariti, A; Berardi, F; Cantore, M; Colabufo, NA; Contino, M; Inglese, C; Niso, M; Paradiso, A; Perrone, MG; Perrone, R; Porcelli, L; Simone, GM | 1 |
| Bernhardt, G; Buschauer, A; Egger, M; Fricker, G; König, B; Kühnle, M; Mahringer, A; Müller, C | 1 |
| Bankstahl, JP; Bankstahl, M; Bauer, F; Chiba, P; Dörner, B; Erker, T; Kuntner, C; Langer, O; Löscher, W; Mairinger, S; Miller, DW; Müllauer, J; Müller, M; Stanek, J; Wanek, T | 1 |
| Bauer, S; Bernhardt, G; Bürger, K; Buschauer, A; Höcherl, P; König, B; Kühnle, M; Puentes, CO | 1 |
| Wang, YS; Wen, LJ; Zhang, J | 1 |
| Fujita, KI; Kato, Y; Kubota, Y; Masuo, Y; Nakamichi, N; Sasaki, Y; Shibutani, T; Yamazaki, E | 1 |
| Wang, XD; Zeng, S | 1 |
| Bankstahl, JP; Bankstahl, M; Erker, T; Kuntner, C; Langer, O; Löscher, W; Mairinger, S; Müller, M; Sauberer, M; Stanek, J; Strommer, S; Wacheck, V; Wanek, T | 1 |
| Boven, E; Hoogsteen, IJ; Kohlhagen, G; Maliepaard, M; Pinedo, HM; Pommier, Y; Scheffer, GL; Scheper, RJ; Schlüper, HM; van Hattum, AH | 1 |
| Herrmann, A; Lage, H; Osada, H; Woehlecke, H | 1 |
| Ejendal, KF; Hrycyna, CA | 1 |
| Bendayan, R; Rauth, AM; Wong, HL; Wu, XY | 1 |
| Du Vignaud, P; Grand-Perret, T; Hyafil, F; Vergely, C | 1 |
| Ballinger, JR; Moore, MJ; Muzzammil, T | 1 |
| Beijnen, JH; Jewell, RC; Koopman, FJ; Malingré, MM; Paul, EM; Rosing, H; Schellens, JH; Ten Bokkel Huinink, WW | 1 |
| Hudes, G | 1 |
| Beijnen, JH; Jewell, RC; Kruijtzer, CM; Paul, EM; Rosing, H; Schellens, JH; Schot, M; ten Bokkel Huinink, WW | 1 |
2 trial(s) available for elacridar and Breast Neoplasms
| Article | Year |
|---|---|
Co-administration of GF120918 significantly increases the systemic exposure to oral paclitaxel in cancer patients.
Topics: Acridines; Administration, Oral; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Biological Availability; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Female; Humans; Infusions, Intravenous; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Neoplasms, Unknown Primary; Paclitaxel; Tetrahydroisoquinolines | 2001 |
Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.
Topics: Acridines; Administration, Oral; Adult; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Breast Neoplasms; Drug Administration Schedule; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Isoquinolines; Middle Aged; Neoplasm Proteins; Tetrahydroisoquinolines; Topotecan | 2002 |
16 other study(ies) available for elacridar and Breast Neoplasms
| Article | Year |
|---|---|
Acridone derivatives: design, synthesis, and inhibition of breast cancer resistance protein ABCG2.
Topics: Acridines; Acridones; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Catalysis; Cell Line, Tumor; Cyclization; Drug Design; Drug Resistance, Neoplasm; Female; Flow Cytometry; Genes, MDR; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mitoxantrone; Neoplasm Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship | 2007 |
Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives.
Topics: Acridines; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Interactions; Drug Resistance, Multiple; Female; Humans; Isoquinolines; Ligands; Quinolines; Structure-Activity Relationship; Tetrahydroisoquinolines | 2008 |
Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Multiple; Female; Humans; Inhibitory Concentration 50; Multidrug Resistance-Associated Protein 2; Neoplasm Proteins; Quinolines; Structure-Activity Relationship | 2009 |
Radiosynthesis and in vivo evaluation of 1-[18F]fluoroelacridar as a positron emission tomography tracer for P-glycoprotein and breast cancer resistance protein.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Breast Neoplasms; Drug Resistance, Multiple; Female; Fluorine Radioisotopes; Humans; Isotope Labeling; Mice; Models, Molecular; Neoplasm Proteins; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Tissue Distribution | 2011 |
Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2).
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Combinatorial Chemistry Techniques; Dose-Response Relationship, Drug; Female; Humans; Inhibitory Concentration 50; Molecular Structure; Neoplasm Proteins; Protein Transport; Quinolines | 2011 |
Nano-gold micelles loaded Dox and Elacridar for reversing drug resistance of breast cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Resistance; Female; Gold; Humans; Metal Nanoparticles; Micelles | 2023 |
Involvement of the Transporters P-Glycoprotein and Breast Cancer Resistance Protein in Dermal Distribution of the Multikinase Inhibitor Regorafenib and Its Active Metabolites.
Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Breast Neoplasms; Diketopiperazines; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Mice; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Skin; Tetrahydroisoquinolines; Tissue Distribution | 2017 |
The transport of gastrodin in Caco-2 cells and uptake in Bcap37 and Bcap37/MDR1 cells.
Topics: Acridines; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzyl Alcohols; Biological Transport; Blood-Brain Barrier; Breast Neoplasms; Caco-2 Cells; Cell Line, Tumor; Drug Resistance, Multiple; Gastrodia; Glucosides; Humans; Plants, Medicinal; Prohibitins; Rhodamine 123; Tetrahydroisoquinolines; Verapamil | 2010 |
A comparative small-animal PET evaluation of [11C]tariquidar, [11C]elacridar and (R)-[11C]verapamil for detection of P-glycoprotein-expressing murine breast cancer.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Breast Neoplasms; Carbon Radioisotopes; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Resistance, Neoplasm; Feasibility Studies; Female; Gene Expression Regulation, Neoplastic; Mice; Phenotype; Positron-Emission Tomography; Quinolines; Tetrahydroisoquinolines; Verapamil | 2012 |
Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity.
Topics: Acridines; Animals; Antigens, CD; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Cell Division; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Female; Humans; Immunoenzyme Techniques; Isoquinolines; Membrane Glycoproteins; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Ovarian Neoplasms; Tetrahydroisoquinolines; Tetraspanin 29; Tetrazolium Salts; Thiazoles; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 2002 |
Reversal of breast cancer resistance protein-mediated drug resistance by tryprostatin A.
Topics: Acridines; Antineoplastic Agents; Breast Neoplasms; Cell Division; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Indole Alkaloids; Kinetics; Mitoxantrone; Piperazines; Stomach Neoplasms; Tetrahydroisoquinolines; Tumor Cells, Cultured | 2003 |
Differential sensitivities of the human ATP-binding cassette transporters ABCG2 and P-glycoprotein to cyclosporin A.
Topics: Acridines; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Cyclosporine; Female; HeLa Cells; Humans; Intracellular Membranes; Kinetics; Microsomes; Neoplasm Proteins; Recombinant Proteins; Substrate Specificity; Tetrahydroisoquinolines; Transfection | 2005 |
Simultaneous delivery of doxorubicin and GG918 (Elacridar) by new polymer-lipid hybrid nanoparticles (PLN) for enhanced treatment of multidrug-resistant breast cancer.
Topics: Acridines; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Doxorubicin; Drug Carriers; Drug Combinations; Drug Compounding; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Lipids; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polymers; Surface Properties; Tetrahydroisoquinolines | 2006 |
In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative.
Topics: Acridines; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Survival; Colonic Neoplasms; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Female; Humans; Isoquinolines; Leukemia P388; Mice; Mice, Inbred DBA; Ovary; Tetrahydroisoquinolines; Tumor Cells, Cultured | 1993 |
99Tcm-sestamibi imaging of inhibition of the multidrug resistance transporter in a mouse xenograft model of human breast cancer.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cyclosporins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Isoquinolines; Mammary Neoplasms, Animal; Mice; Mice, SCID; Neoplasm Transplantation; Radionuclide Imaging; Sensitivity and Specificity; Technetium Tc 99m Sestamibi; Tetrahydroisoquinolines; Transplantation, Heterologous | 1999 |
Boosting bioavailability of topotecan: what do we gain?
Topics: Acridines; Administration, Oral; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Intestinal Absorption; Isoquinolines; Neoplasm Proteins; Tetrahydroisoquinolines; Topoisomerase I Inhibitors; Topotecan | 2002 |