elacridar has been researched along with Benign Neoplasms in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Akra, L; Bae, DH; Huang, MLH; Jansson, PJ; Lane, DJR; Park, KC; Richardson, DR; Sahni, S | 1 |
| Lamprecht, A; Singh, MS | 1 |
| Hu, Y; Hu, Z; Huang, W; Li, Y; Wu, J; Zhou, Z | 1 |
| de Boer-Dennert, M; de Leeuw, K; Jewell, RC; Luyten, GP; Paul, EM; Planting, AS; Purvis, NB; Sonneveld, P; Sparreboom, A; van der Burg, ME; van der Gaast, A; Verweij, J; Wissel, PS | 1 |
| Hardwick, LJ; van Veen, HW; Velamakanni, S | 1 |
| Beijnen, JH; Jewell, RC; Kuppens, IE; Mangum, SG; Paul, EM; Radema, SA; Schellens, JH; Voest, EE; Witteveen, EO | 1 |
| Ballinger, JR; Moore, MJ; Muzzammil, T | 1 |
1 review(s) available for elacridar and Benign Neoplasms
| Article | Year |
|---|---|
The emerging pharmacotherapeutic significance of the breast cancer resistance protein (ABCG2).
Topics: Acridines; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Neoplasms; Technology, Pharmaceutical; Tetrahydroisoquinolines; Topotecan | 2007 |
2 trial(s) available for elacridar and Benign Neoplasms
| Article | Year |
|---|---|
A phase I and pharmacologic study of the MDR converter GF120918 in combination with doxorubicin in patients with advanced solid tumors.
Topics: Acridines; Administration, Oral; Adult; Aged; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Drug Interactions; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Tetrahydroisoquinolines | 2005 |
A phase I, randomized, open-label, parallel-cohort, dose-finding study of elacridar (GF120918) and oral topotecan in cancer patients.
Topics: Acridines; Administration, Oral; Adult; Aged; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cohort Studies; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Proteins; Neoplasms; Research Design; Tetrahydroisoquinolines; Topotecan | 2007 |
4 other study(ies) available for elacridar and Benign Neoplasms
| Article | Year |
|---|---|
Tumor stressors induce two mechanisms of intracellular P-glycoprotein-mediated resistance that are overcome by lysosomal-targeted thiosemicarbazones.
Topics: Acridines; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Hypoxia-Inducible Factor 1, alpha Subunit; Lysosomes; Models, Biological; Neoplasm Proteins; Neoplasms; Organelle Biogenesis; Protein Transport; RNA Interference; Tetrahydroisoquinolines; Thiosemicarbazones; Tumor Microenvironment | 2018 |
Cargoing P-gp inhibitors via nanoparticle sensitizes tumor cells against doxorubicin.
Topics: Acridines; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Carriers; Drug Resistance, Neoplasm; Humans; Nanoparticles; Neoplasms; Polyvinyl Alcohol; Sodium Dodecyl Sulfate; Surface-Active Agents; Tetrahydroisoquinolines; Verapamil | 2015 |
HZ08 reverse P-glycoprotein mediated multidrug resistance in vitro and in vivo.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Dogs; Drug Resistance, Multiple; Humans; Isoquinolines; KB Cells; Madin Darby Canine Kidney Cells; Mice; Neoplasms; Tetrahydroisoquinolines; Transplantation, Heterologous; Verapamil | 2015 |
In vitro comparison of sestamibi, tetrofosmin, and furifosmin as agents for functional imaging of multidrug resistance in tumors.
Topics: Acridines; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporins; Drug Resistance, Neoplasm; Furans; Humans; Isoquinolines; Neoplasms; Organophosphorus Compounds; Organotechnetium Compounds; Technetium Tc 99m Sestamibi; Tetrahydroisoquinolines; Tomography, Emission-Computed, Single-Photon; Tumor Cells, Cultured | 2000 |