Compounds > elacridar
Page last updated: 2024-09-03

elacridar and Astrocytoma, Grade IV

elacridar has been researched along with Astrocytoma, Grade IV in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Crish, JF; Elmquist, WF; Gampa, G; Hinojosa, AQ; Kenchappa, RS; Kim, M; Luu, A; Mohammad, AS; Parrish, KE; Rosenfeld, SS; Sarkaria, JN; West, R1
Allhenn, D; Béduneau, A; Lamprecht, A; Neumann, D; Pellequer, Y1
Beijnen, JH; Beumer, JH; Buil, LC; Christner, SM; de Gooijer, MC; Lin, F; Roig, EM; van Tellingen, O; Würdinger, T1
Bakken, K; Elmquist, WF; Mittapalli, RK; Parrish, KE; Pokorny, J; Sarkaria, JN1
Agarwal, S; Decker, SA; Donelson, R; Elmquist, WF; Gallardo, JL; Mittapalli, RK; Ohlfest, JR; Pokorny, JL; Santacruz, KS; Sarkaria, JN; Seiler, C; Zellmer, DM1
Bernhardt, G; Buschauer, A; Gartner, M; Giannis, A; Gross, D; Müller, C; Sarli, V1

Other Studies

6 other study(ies) available for elacridar and Astrocytoma, Grade IV

ArticleYear
Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma.
    Scientific reports, 2020, 04-16, Volume: 10, Issue:1

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Benzamides; Blood-Brain Barrier; Brain; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Glioblastoma; Humans; Kinesins; Mice; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Proteins; Quinazolines; Tetrahydroisoquinolines; Xenograft Model Antitumor Assays

2020
A "drug cocktail" delivered by microspheres for the local treatment of rat glioblastoma.
    Journal of microencapsulation, 2013, Volume: 30, Issue:7

    Topics: Acridines; Animals; Antineoplastic Agents, Phytogenic; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Carriers; Etoposide; Glioblastoma; Lactic Acid; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrazoles; Rats; Rats, Inbred F344; Sulfonamides; Tetrahydroisoquinolines

2013
ABCB1, ABCG2, and PTEN determine the response of glioblastoma to temozolomide and ABT-888 therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, May-15, Volume: 20, Issue:10

    Topics: Acridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzimidazoles; Blood-Brain Barrier; Blotting, Western; Brain; Cell Line, Tumor; Dacarbazine; Dogs; Glioblastoma; Humans; Immunohistochemistry; Kaplan-Meier Estimate; LLC-PK1 Cells; Madin Darby Canine Kidney Cells; Metabolic Clearance Rate; Mice, Knockout; Mice, Nude; PTEN Phosphohydrolase; Swine; Temozolomide; Tetrahydroisoquinolines; Treatment Outcome

2014
Efflux transporters at the blood-brain barrier limit delivery and efficacy of cyclin-dependent kinase 4/6 inhibitor palbociclib (PD-0332991) in an orthotopic brain tumor model.
    The Journal of pharmacology and experimental therapeutics, 2015, Volume: 355, Issue:2

    Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Dogs; Drug Resistance, Neoplasm; Drug Synergism; Female; Glioblastoma; Heterografts; Madin Darby Canine Kidney Cells; Male; Mice; Mice, Knockout; Mice, Nude; Neoplasm Transplantation; Piperazines; Pyridines; Tetrahydroisoquinolines

2015
Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:10

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Dasatinib; Disease Models, Animal; Endothelium, Vascular; Glioblastoma; Humans; Mice; Mice, Knockout; Molecular Targeted Therapy; Oncogenes; Permeability; Pyrimidines; Signal Transduction; Survival Analysis; Tetrahydroisoquinolines; Thiazoles; Tight Junctions; Tissue Distribution; Treatment Outcome; Xenograft Model Antitumor Assays

2012
Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:2

    Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Flow Cytometry; Fluoresceins; Glioblastoma; Humans; Insecticides; Kinesins; Molecular Structure; Paclitaxel; Pyrimidines; Quinazolines; Rotenone; Spindle Apparatus; Tetrahydroisoquinolines; Thiones; Time Factors; Tubulin; Tubulin Modulators; Vinblastine

2007