Page last updated: 2024-10-26

eicosapentaenoic acid ethyl ester and Schizophrenia

eicosapentaenoic acid ethyl ester has been researched along with Schizophrenia in 9 studies

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"This study determined if augmentation of neuroleptics with 3 g/day of ethyl eicosapentaenoic acid (EPA) improves symptoms and cognition in patients with schizophrenia or schizoaffective disorder."9.09A placebo-controlled trial of omega-3 fatty acid (ethyl eicosapentaenoic acid) supplementation for residual symptoms and cognitive impairment in schizophrenia. ( Boronow, J; Dickerson, F; Fenton, WS; Hibbeln, JR; Knable, M, 2001)
"This study determined if augmentation of neuroleptics with 3 g/day of ethyl eicosapentaenoic acid (EPA) improves symptoms and cognition in patients with schizophrenia or schizoaffective disorder."5.09A placebo-controlled trial of omega-3 fatty acid (ethyl eicosapentaenoic acid) supplementation for residual symptoms and cognitive impairment in schizophrenia. ( Boronow, J; Dickerson, F; Fenton, WS; Hibbeln, JR; Knable, M, 2001)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Qiao, Y1
Mei, Y1
Han, H1
Liu, F1
Yang, XM1
Shao, Y1
Xie, B1
Long, B1
Bentsen, H2
Landrø, NI1
Osnes, K1
Refsum, H1
Solberg, DK1
Bøhmer, T1
Veerman, SR1
Schulte, PF1
Begemann, MJ1
de Haan, L1
Pawełczyk, T2
Grancow, M1
Kotlicka-Antczak, M2
Trafalska, E2
Gębski, P1
Szemraj, J1
Żurner, N1
Pawełczyk, A2
Grancow-Grabka, M1
Horrobin, DF1
Berger, GE1
Smesny, S1
Amminger, GP1
Fenton, WS1
Dickerson, F1
Boronow, J1
Hibbeln, JR1
Knable, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Omega-3 Fatty Acids in First-episode Schizophrenia - a Randomized Controlled Study of Efficacy and Relapse Prevention (OFFER). Rationale, Design, and Methods.[NCT02210962]Phase 480 participants (Anticipated)Interventional2011-09-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for eicosapentaenoic acid ethyl ester and Schizophrenia

ArticleYear
Non-glutamatergic clozapine augmentation strategies: a review and meta-analysis.
    Pharmacopsychiatry, 2014, Volume: 47, Issue:7

    Topics: Antidepressive Agents; Antipsychotic Agents; Brief Psychiatric Rating Scale; Clozapine; Double-Blind

2014
Bioactive lipids in schizophrenia.
    International review of psychiatry (Abingdon, England), 2006, Volume: 18, Issue:2

    Topics: Antipsychotic Agents; Arachidonic Acid; Brain; Clinical Trials as Topic; Drug Therapy, Combination;

2006

Trials

5 trials available for eicosapentaenoic acid ethyl ester and Schizophrenia

ArticleYear
Neurocognitive effects of an omega-3 fatty acid and vitamins E+C in schizophrenia: A randomised controlled trial.
    Prostaglandins, leukotrienes, and essential fatty acids, 2018, Volume: 136

    Topics: Adult; Antipsychotic Agents; Ascorbic Acid; Attention; Eicosapentaenoic Acid; Executive Function; Fa

2018
A randomized placebo-controlled trial of an omega-3 fatty acid and vitamins E+C in schizophrenia.
    Translational psychiatry, 2013, Dec-17, Volume: 3

    Topics: Adolescent; Adult; Antipsychotic Agents; Ascorbic Acid; Double-Blind Method; Drug Therapy, Combinati

2013
Omega-3 fatty acids in first-episode schizophrenia - a randomized controlled study of efficacy and relapse prevention (OFFER): rationale, design, and methods.
    BMC psychiatry, 2015, May-02, Volume: 15

    Topics: Adolescent; Adult; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, U

2015
A randomized controlled study of the efficacy of six-month supplementation with concentrated fish oil rich in omega-3 polyunsaturated fatty acids in first episode schizophrenia.
    Journal of psychiatric research, 2016, Volume: 73

    Topics: Adolescent; Adult; Age Factors; Antipsychotic Agents; Dietary Supplements; Double-Blind Method; Eico

2016
A placebo-controlled trial of omega-3 fatty acid (ethyl eicosapentaenoic acid) supplementation for residual symptoms and cognitive impairment in schizophrenia.
    The American journal of psychiatry, 2001, Volume: 158, Issue:12

    Topics: Adult; Antipsychotic Agents; Cognition Disorders; Double-Blind Method; Drug Therapy, Combination; Ei

2001

Other Studies

2 other studies available for eicosapentaenoic acid ethyl ester and Schizophrenia

ArticleYear
Effects of Omega-3 in the treatment of violent schizophrenia patients.
    Schizophrenia research, 2018, Volume: 195

    Topics: Adult; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Female; Humans; Male;

2018
omega-3 Fatty acid for schizophrenia.
    The American journal of psychiatry, 2003, Volume: 160, Issue:1

    Topics: Antipsychotic Agents; Drug Therapy, Combination; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Humans

2003