eicosapentaenoic acid ethyl ester has been researched along with Disease Models, Animal in 19 studies
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study examined the effects of eicosapentaenoic acid (EPA) administration on the prevention of early hearing loss in diabetic mice." | 8.31 | Prevention of progressive hearing loss in a mouse model of diabetes by oral intake of eicosapentaenoic acid ethyl ester. ( Hashimoto, M; Matsuura, T; Sugahara, K; Tsuda, J; Yamamoto, Y; Yamashita, H, 2023) |
| "This study assessed the effects of eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA) on normal cardiac function (part 1) and congestive heart failure (CHF) (part 2) through electrocardiogram analysis and determination of EPA, DHA, and arachidonic acid (AA) concentrations in rat hearts." | 7.80 | Oral administration of eicosapentaenoic acid or docosahexaenoic acid modifies cardiac function and ameliorates congestive heart failure in male rats. ( Hirakawa, E; Janjua, N; Kabuto, H; Mankura, M; Takayama, F; Yamanushi, TT, 2014) |
| "The purpose of the present study was to test whether hyperlipidaemia and insulin resistance in type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats can be improved by dietary supplementation with purified eicosapentaenoic acid (EPA) or oleic acid (OA)." | 7.71 | Effect of eicosapentaenoic acid ethyl ester v. oleic acid-rich safflower oil on insulin resistance in type 2 diabetic model rats with hypertriacylglycerolaemia. ( Ishimura, N; Mawatari, K; Minami, A; Nakaya, Y; Okada, K; Sakamoto, S; Takishita, E, 2002) |
| "We investigated the effect of long-term administration of highly purified eicosapentaenoic acid ethyl ester (EPA-E), an n-3 polyunsaturated fatty acid derived from fish oil, in comparison to the effects of lard, olive oil, safflower oil, or distilled water as the control on the development of insulin resistance in Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of spontaneous non-insulin-dependent diabetes mellitus (NIDDM) with obesity." | 7.69 | Influence of highly purified eicosapentaenoic acid ethyl ester on insulin resistance in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus. ( Hata, S; Ikeda, Y; Ishikawa, T; Katoh, S; Mori, Y; Murakawa, Y; Nobukata, H; Shibutani, Y; Tajima, N; Yokoyama, J, 1997) |
| "This study examined the effects of eicosapentaenoic acid (EPA) administration on the prevention of early hearing loss in diabetic mice." | 4.31 | Prevention of progressive hearing loss in a mouse model of diabetes by oral intake of eicosapentaenoic acid ethyl ester. ( Hashimoto, M; Matsuura, T; Sugahara, K; Tsuda, J; Yamamoto, Y; Yamashita, H, 2023) |
| " Eicosapentaenoic acid-enriched phospholipids (EPA-PL) significantly ameliorate insulin resistance and elevate the level of hepatic lipolysis, which may have a synergistic effect with SCS in alleviating obesity-related insulin resistance via multiple mechanisms." | 3.91 | Synergistic effect of sea cucumber saponins and EPA-enriched phospholipids on insulin resistance in high-fat diet-induced obese mice. ( Ding, L; Han, XQ; Shi, HH; Wang, YM; Xue, CH; Zhang, LY; Zhang, TT, 2019) |
| "This study assessed the effects of eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA) on normal cardiac function (part 1) and congestive heart failure (CHF) (part 2) through electrocardiogram analysis and determination of EPA, DHA, and arachidonic acid (AA) concentrations in rat hearts." | 3.80 | Oral administration of eicosapentaenoic acid or docosahexaenoic acid modifies cardiac function and ameliorates congestive heart failure in male rats. ( Hirakawa, E; Janjua, N; Kabuto, H; Mankura, M; Takayama, F; Yamanushi, TT, 2014) |
| "The effect of ethyl eicosapentanoate (EPA-E) on statin-induced rhabdomyolysis was investigated by co-administration of EPA-E and pravastatin (PV), as a typical statin, to Eisai hyperbilirubinemic rats (EHBR)." | 3.73 | Improving effect of ethyl eicosapentanoate on statin-induced rhabdomyolysis in Eisai hyperbilirubinemic rats. ( Kakinuma, C; Naba, H; Ogihara, T; Ohnishi, S, 2006) |
| "The purpose of the present study was to test whether hyperlipidaemia and insulin resistance in type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats can be improved by dietary supplementation with purified eicosapentaenoic acid (EPA) or oleic acid (OA)." | 3.71 | Effect of eicosapentaenoic acid ethyl ester v. oleic acid-rich safflower oil on insulin resistance in type 2 diabetic model rats with hypertriacylglycerolaemia. ( Ishimura, N; Mawatari, K; Minami, A; Nakaya, Y; Okada, K; Sakamoto, S; Takishita, E, 2002) |
| "We investigated the effect of long-term administration of highly purified eicosapentaenoic acid ethyl ester (EPA-E), an n-3 polyunsaturated fatty acid derived from fish oil, in comparison to the effects of lard, olive oil, safflower oil, or distilled water as the control on the development of insulin resistance in Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of spontaneous non-insulin-dependent diabetes mellitus (NIDDM) with obesity." | 3.69 | Influence of highly purified eicosapentaenoic acid ethyl ester on insulin resistance in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus. ( Hata, S; Ikeda, Y; Ishikawa, T; Katoh, S; Mori, Y; Murakawa, Y; Nobukata, H; Shibutani, Y; Tajima, N; Yokoyama, J, 1997) |
| "Cystamine treatment of various genetic models of HD demonstrated protection against neurodegeneration and/or improvement in behavior." | 1.37 | Cystamine and ethyl-eicosapentaenoic acid treatment fail to prevent malonate-induced striatal toxicity in mice. ( Leavitt, BR; Sivananthan, SN, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Vander Ploeg, M | 1 |
| Quinn, K | 1 |
| Armstrong, M | 1 |
| Manke, J | 1 |
| Reisdorph, N | 1 |
| Shaikh, SR | 1 |
| Matsuura, T | 1 |
| Sugahara, K | 1 |
| Yamamoto, Y | 1 |
| Tsuda, J | 1 |
| Hashimoto, M | 1 |
| Yamashita, H | 1 |
| Wang, CC | 1 |
| Du, L | 1 |
| Shi, HH | 2 |
| Ding, L | 2 |
| Yanagita, T | 1 |
| Xue, CH | 2 |
| Wang, YM | 2 |
| Zhang, TT | 2 |
| Fujii, M | 1 |
| Ohyanagi, C | 1 |
| Kawaguchi, N | 1 |
| Matsuda, H | 1 |
| Miyamoto, Y | 1 |
| Ohya, S | 1 |
| Nabe, T | 1 |
| Han, XQ | 1 |
| Zhang, LY | 1 |
| Yamanushi, TT | 1 |
| Kabuto, H | 1 |
| Hirakawa, E | 1 |
| Janjua, N | 1 |
| Takayama, F | 1 |
| Mankura, M | 1 |
| Song, C | 1 |
| Zhang, XY | 1 |
| Manku, M | 1 |
| Billman, GE | 1 |
| Nishijima, Y | 1 |
| Belevych, AE | 1 |
| Terentyev, D | 1 |
| Xu, Y | 1 |
| Haizlip, KM | 1 |
| Monasky, MM | 1 |
| Hiranandani, N | 1 |
| Harris, WS | 1 |
| Gyorke, S | 1 |
| Carnes, CA | 1 |
| Janssen, PM | 1 |
| Sivananthan, SN | 1 |
| Leavitt, BR | 2 |
| Van Raamsdonk, JM | 1 |
| Pearson, J | 1 |
| Rogers, DA | 1 |
| Lu, G | 1 |
| Barakauskas, VE | 1 |
| Barr, AM | 1 |
| Honer, WG | 1 |
| Hayden, MR | 1 |
| Naba, H | 1 |
| Kakinuma, C | 1 |
| Ohnishi, S | 1 |
| Ogihara, T | 1 |
| Sato, M | 1 |
| Katsuki, Y | 2 |
| Kanehiro, H | 2 |
| Iimura, M | 1 |
| Akada, Y | 1 |
| Mizota, M | 2 |
| Kunihiro, Y | 1 |
| Robinson, DR | 1 |
| Xu, LL | 1 |
| Tateno, S | 1 |
| Guo, M | 1 |
| Colvin, RB | 1 |
| Mori, Y | 1 |
| Murakawa, Y | 1 |
| Katoh, S | 1 |
| Hata, S | 1 |
| Yokoyama, J | 1 |
| Tajima, N | 1 |
| Ikeda, Y | 1 |
| Nobukata, H | 1 |
| Ishikawa, T | 1 |
| Shibutani, Y | 1 |
| Mizuguchi, K | 2 |
| Yano, T | 1 |
| Kawano, H | 1 |
| Abei, M | 1 |
| Tanaka, N | 1 |
| Katsumata, T | 1 |
| Katayama, Y | 1 |
| Obo, R | 1 |
| Muramatsu, H | 1 |
| Ohtori, T | 1 |
| Terashi, A | 1 |
| Shimizu, T | 1 |
| Iwamoto, T | 1 |
| Itou, S | 1 |
| Iwata, N | 1 |
| Endo, T | 1 |
| Takasaki, M | 1 |
| Minami, A | 1 |
| Ishimura, N | 1 |
| Sakamoto, S | 1 |
| Takishita, E | 1 |
| Mawatari, K | 1 |
| Okada, K | 1 |
| Nakaya, Y | 1 |
| Endo, S | 1 |
| Miyata, H | 1 |
| Kojima, M | 1 |
| Okada, M | 1 |
| Takase, A | 1 |
| Ishiguro, J | 1 |
19 other studies available for eicosapentaenoic acid ethyl ester and Disease Models, Animal
| Article | Year |
|---|---|
SPM pathway marker analysis of the brains of obese mice in the absence and presence of eicosapentaenoic acid ethyl esters.
Topics: Animals; Brain Chemistry; Diet, High-Fat; Disease Models, Animal; Eicosapentaenoic Acid; Lipoxins; M | 2021 |
Prevention of progressive hearing loss in a mouse model of diabetes by oral intake of eicosapentaenoic acid ethyl ester.
Topics: Animals; Cochlea; Deafness; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Mode | 2023 |
Dietary EPA-Enriched Phospholipids Alleviate Chronic Stress and LPS-Induced Depression- and Anxiety-Like Behavior by Regulating Immunity and Neuroinflammation.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Corticosterone; Depression; Disease Models, Animal; Eicos | 2021 |
Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum.
Topics: Administration, Oral; Animals; Biological Availability; Ceramides; Dermatitis, Atopic; Diet; Disease | 2018 |
Synergistic effect of sea cucumber saponins and EPA-enriched phospholipids on insulin resistance in high-fat diet-induced obese mice.
Topics: Adipose Tissue; Adipose Tissue, White; Animals; Chemokine CCL2; Diet, High-Fat; Disease Models, Anim | 2019 |
Oral administration of eicosapentaenoic acid or docosahexaenoic acid modifies cardiac function and ameliorates congestive heart failure in male rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dietary Supplements; Disease Models, Animal; Docos | 2014 |
Increased phospholipase A2 activity and inflammatory response but decreased nerve growth factor expression in the olfactory bulbectomized rat model of depression: effects of chronic ethyl-eicosapentaenoate treatment.
Topics: Analysis of Variance; Animals; Celecoxib; Corticosterone; Corticotropin-Releasing Hormone; Cyclooxyg | 2009 |
Effects of dietary omega-3 fatty acids on ventricular function in dogs with healed myocardial infarctions: in vivo and in vitro studies.
Topics: Animals; Calcium; Dietary Supplements; Disease Models, Animal; Docosahexaenoic Acids; Dogs; Dose-Res | 2010 |
Cystamine and ethyl-eicosapentaenoic acid treatment fail to prevent malonate-induced striatal toxicity in mice.
Topics: Animals; Corpus Striatum; Cystamine; Disease Models, Animal; Eicosapentaenoic Acid; Huntington Disea | 2011 |
Ethyl-EPA treatment improves motor dysfunction, but not neurodegeneration in the YAC128 mouse model of Huntington disease.
Topics: Animals; Behavior, Animal; Cell Count; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphopr | 2005 |
Improving effect of ethyl eicosapentanoate on statin-induced rhabdomyolysis in Eisai hyperbilirubinemic rats.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Eicosapentaeno | 2006 |
Effects of ethyl all-cis-5,8,11,14,17-icosapentaenoate on the physical properties of arterial walls in high cholesterol diet-fed rabbits.
Topics: Administration, Oral; Animals; Aorta; Arteriosclerosis Obliterans; Cholesterol, Dietary; Disease Mod | 1993 |
Suppression of autoimmune disease by dietary n-3 fatty acids.
Topics: Animals; Autoimmune Diseases; Cattle; Dietary Fats; Disease Models, Animal; Docosahexaenoic Acids; D | 1993 |
Influence of highly purified eicosapentaenoic acid ethyl ester on insulin resistance in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus.
Topics: Animals; Blood Glucose; Body Composition; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, A | 1997 |
[Preventive effects of eicosapentaenoic acid (EPA) on cholesterol gallstone formation in hamsters].
Topics: Animals; Bile; Cholelithiasis; Cholesterol; Cricetinae; Disease Models, Animal; Eicosapentaenoic Aci | 1997 |
Delayed administration of ethyl eicosapentate improves local cerebral blood flow and metabolism without affecting infarct volumes in the rat focal ischemic model.
Topics: Animals; Autoradiography; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Delayed- | 1999 |
Effect of ethyl icosapentaenoate (EPA) on the concentration of tumor necrosis factor (TNF) and interleukin-1 (IL-1) in the carotid artery of cuff-sheathed rabbit models.
Topics: Animals; Arteriosclerosis; Carotid Arteries; Disease Models, Animal; Eicosapentaenoic Acid; Interleu | 2001 |
Effect of eicosapentaenoic acid ethyl ester v. oleic acid-rich safflower oil on insulin resistance in type 2 diabetic model rats with hypertriacylglycerolaemia.
Topics: Abdomen; Adipose Tissue; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Dietary Sup | 2002 |
[Pharmacological studies of eicosapentaenoic acid ethylester (EPA-E) on high cholesterol diet-fed rabbits].
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Blood Platelets; Cholesterol, Dietary; Disease Models, A | 1988 |