Page last updated: 2024-10-26

eicosapentaenoic acid ethyl ester and Coronary Artery Disease

eicosapentaenoic acid ethyl ester has been researched along with Coronary Artery Disease in 7 studies

Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.

Research Excerpts

ExcerptRelevanceReference
"Though statin therapy is known to slow coronary atherosclerosis progression and reduce cardiovascular (CV) events, significant CV risk still remains."3.01Effect of icosapent ethyl on progression of coronary atherosclerosis in patients with elevated triglycerides on statin therapy: a prospective, placebo-controlled randomized trial (EVAPORATE): interim results. ( Bhatt, DL; Budoff, MJ; Kinninger, A; Lakshmanan, S; Le Pa, VT; May, HT; Muhlestein, JB; Nelson, JR; Roy, SK; Shaikh, K; Shekar, C; Tayek, J, 2021)
"Patients had to have coronary atherosclerosis as documented by MDCT (one or more angiographic stenoses with ≥20% narrowing), be on statin therapy, and have persistently elevated triglyceride (TG) levels."2.94Effect of icosapent ethyl on progression of coronary atherosclerosis in patients with elevated triglycerides on statin therapy: final results of the EVAPORATE trial. ( Bhatt, DL; Budoff, MJ; Kinninger, A; Lakshmanan, S; Le, VT; May, HT; Muhlestein, JB; Nelson, JR; Roy, SK; Shaikh, K; Shekar, C; Tayek, J, 2020)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's5 (71.43)2.80

Authors

AuthorsStudies
Chapman, MJ1
Zamorano, JL1
Parhofer, KG1
Rabbat, MG1
Lakshmanan, S3
Benjamin, MM1
Doros, G1
Kinninger, A3
Budoff, MJ3
Bhatt, DL3
Muhlestein, JB2
Le Pa, VT1
May, HT3
Shaikh, K2
Shekar, C2
Roy, SK2
Tayek, J2
Nelson, JR3
Le, VT2
Tokgozoglu, L1
Catapano, AL1
Budoff, M1
Brent Muhlestein, J1
Roy, S1
Lan, NSR1
Fegan, PG1
Yeap, BB1
Rankin, JM1
Watts, GF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of the Effect of Eicosapentaenoic Acid (EPA) on Markers of Atherothrombosis in Patients With Type-2 Diabetes[NCT06129526]Phase 4450 participants (Anticipated)Interventional2023-12-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for eicosapentaenoic acid ethyl ester and Coronary Artery Disease

ArticleYear
Reducing residual cardiovascular risk in Europe: Therapeutic implications of European medicines agency approval of icosapent ethyl/eicosapentaenoic acid.
    Pharmacology & therapeutics, 2022, Volume: 237

    Topics: Adult; Atherosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Eicosapentaenoic Acid; Hea

2022

Trials

3 trials available for eicosapentaenoic acid ethyl ester and Coronary Artery Disease

ArticleYear
Effect of icosapent ethyl on progression of coronary atherosclerosis in patients with elevated triglycerides on statin therapy: a prospective, placebo-controlled randomized trial (EVAPORATE): interim results.
    Cardiovascular research, 2021, 03-21, Volume: 117, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Computed Tomography Angiography; Coronary Angiography; C

2021
Effect of icosapent ethyl on progression of coronary atherosclerosis in patients with elevated triglycerides on statin therapy: final results of the EVAPORATE trial.
    European heart journal, 2020, 10-21, Volume: 41, Issue:40

    Topics: Aged; Coronary Artery Disease; Eicosapentaenoic Acid; Female; Humans; Hydroxymethylglutaryl-CoA Redu

2020
Effect of Vascepa (icosapent ethyl) on progression of coronary atherosclerosis in patients with elevated triglycerides (200-499 mg/dL) on statin therapy: Rationale and design of the EVAPORATE study.
    Clinical cardiology, 2018, Volume: 41, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Biomarkers; Coronary Artery Disease; Disease Progre

2018

Other Studies

3 other studies available for eicosapentaenoic acid ethyl ester and Coronary Artery Disease

ArticleYear
Benefit of icosapent ethyl on coronary physiology assessed by computed tomography angiography fractional flow reserve: EVAPORATE-FFRCT.
    European heart journal. Cardiovascular Imaging, 2023, 06-21, Volume: 24, Issue:7

    Topics: Computed Tomography Angiography; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; C

2023
Can EPA evaporate plaques?
    European heart journal, 2020, 10-21, Volume: 41, Issue:40

    Topics: Coronary Artery Disease; Eicosapentaenoic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibito

2020
Icosapent ethyl for dyslipidaemia in patients with diabetes and coronary artery disease: Act now to reduce it.
    Diabetes, obesity & metabolism, 2019, Volume: 21, Issue:7

    Topics: Aged; Coronary Artery Disease; Diabetes Mellitus, Type 2; Dyslipidemias; Eicosapentaenoic Acid; Fema

2019