eicosapentaenoic acid ethyl ester has been researched along with Alzheimer Disease in 4 studies
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pre-administration of TAK-085 (highly purified and concentrated n-3 fatty acids containing eicosapentaenoic acid ethyl ester and docosahexaenoic acid ethyl ester) at 300 mg kg(-1) day(-1) for 12 weeks significantly reduced the number of reference memory errors in an 8-arm radial maze, suggesting that long-term administration of TAK-085 improves cognitive leaning ability in rats." | 1.37 | Protective effects of prescription n-3 fatty acids against impairment of spatial cognitive learning ability in amyloid β-infused rats. ( Gamoh, S; Haque, AM; Hashimoto, M; Katakura, M; Shahdat, H; Shido, O; Tanabe, Y; Tozawa, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giudici, KV | 1 |
| de Souto Barreto, P | 1 |
| Beard, J | 1 |
| Cantet, C | 1 |
| Araujo de Carvalho, I | 1 |
| Rolland, Y | 1 |
| Vellas, B | 1 |
| Xu, ZJ | 1 |
| Li, Q | 1 |
| Ding, L | 1 |
| Shi, HH | 1 |
| Xue, CH | 1 |
| Mao, XZ | 1 |
| Wang, YM | 1 |
| Zhang, TT | 1 |
| Hashimoto, M | 1 |
| Tozawa, R | 1 |
| Katakura, M | 1 |
| Shahdat, H | 1 |
| Haque, AM | 1 |
| Tanabe, Y | 1 |
| Gamoh, S | 1 |
| Shido, O | 1 |
| Boston, PF | 1 |
| Bennett, A | 1 |
| Horrobin, DF | 1 |
| Bennett, CN | 1 |
2 trials available for eicosapentaenoic acid ethyl ester and Alzheimer Disease
| Article | Year |
|---|---|
Effect of long-term omega-3 supplementation and a lifestyle multidomain intervention on intrinsic capacity among community-dwelling older adults: Secondary analysis of a randomized, placebo-controlled trial (MAPT study).
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Dietary Supplements; Docosahexaenoic Acids; E | 2020 |
Ethyl-EPA in Alzheimer's disease--a pilot study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Eicosapentaenoic Acid; Erythrocyte Membrane; | 2004 |
2 other studies available for eicosapentaenoic acid ethyl ester and Alzheimer Disease
| Article | Year |
|---|---|
A comparative study of the effects of phosphatidylserine rich in DHA and EPA on Aβ-induced Alzheimer's disease using cell models.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; CHO Cells; Cricetulus; Docosahexae | 2021 |
Protective effects of prescription n-3 fatty acids against impairment of spatial cognitive learning ability in amyloid β-infused rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cerebral Cortex; Cerebral Ventricles; Cognition D | 2011 |