eflornithine has been researched along with Weight Gain in 3 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The toxicity of DFMO in combination with TAM was evaluated in female rats following 13 weeks of daily administration by gavage." | 1.30 | Difluoromethylornithine in combination with tamoxifen in female rats: 13-week oral toxicity study. ( Brown, AP; Crowell, JA; Levine, BS; Morrissey, RL, 1999) |
| " The higher dosage (0." | 1.27 | Preventive treatment of rabbit coccidiosis with alpha-difluoromethylornithine. ( Alunda, JM; Ordóñez-Escudero, D; San Martín-Núñez, BV, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, AP | 1 |
| Morrissey, RL | 1 |
| Crowell, JA | 1 |
| Levine, BS | 1 |
| McWilliams, ML | 1 |
| Chen, GD | 1 |
| Fechter, LD | 1 |
| San Martín-Núñez, BV | 1 |
| Ordóñez-Escudero, D | 1 |
| Alunda, JM | 1 |
3 other studies available for eflornithine and Weight Gain
| Article | Year |
|---|---|
Difluoromethylornithine in combination with tamoxifen in female rats: 13-week oral toxicity study.
Topics: Administration, Oral; Alanine Transaminase; Animals; Anticarcinogenic Agents; Blood Proteins; Bone M | 1999 |
Characterization of the ototoxicity of difluoromethylornithine and its enantiomers.
Topics: Animals; Auditory Threshold; Deafness; Eflornithine; Enzyme Inhibitors; Guinea Pigs; Hair Cells, Aud | 2000 |
Preventive treatment of rabbit coccidiosis with alpha-difluoromethylornithine.
Topics: Animals; Aspartate Aminotransferases; Coccidiosis; Eating; Eflornithine; Feces; Intestinal Diseases, | 1988 |