eflornithine has been researched along with Uterine Neoplasms in 3 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Uterine Neoplasms: Tumors or cancer of the UTERUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although tamoxifen appears to markedly reduce breast cancer risk in women with a prior diagnosis of atypical hyperplasia or in situ carcinoma, it is not clear what other groups of women receive substantial benefit." | 8.81 | Beyond tamoxifen new endpoints for breast cancer chemoprevention, new drugs for breast cancer prevention. ( Fabian, CJ; Kimler, BF, 2001) |
| "Although tamoxifen appears to markedly reduce breast cancer risk in women with a prior diagnosis of atypical hyperplasia or in situ carcinoma, it is not clear what other groups of women receive substantial benefit." | 4.81 | Beyond tamoxifen new endpoints for breast cancer chemoprevention, new drugs for breast cancer prevention. ( Fabian, CJ; Kimler, BF, 2001) |
| "Primary cultures of human uterine leiomyomas and matched normal myometrium were established from hysterectomy specimens." | 1.32 | The chemopreventive agents 4-HPR and DFMO inhibit growth and induce apoptosis in uterine leiomyomas. ( Broaddus, RR; Hsu, CJ; Wang, J; Xie, S; Zhang, S; Zou, C, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Broaddus, RR | 1 |
| Xie, S | 1 |
| Hsu, CJ | 1 |
| Wang, J | 1 |
| Zhang, S | 1 |
| Zou, C | 1 |
| Fabian, CJ | 1 |
| Kimler, BF | 1 |
| Holinka, CF | 1 |
| Gurpide, E | 1 |
1 review available for eflornithine and Uterine Neoplasms
| Article | Year |
|---|---|
Beyond tamoxifen new endpoints for breast cancer chemoprevention, new drugs for breast cancer prevention.
Topics: Aneuploidy; Angiogenesis Inhibitors; Anticarcinogenic Agents; Apoptosis; Aromatase Inhibitors; Breas | 2001 |
2 other studies available for eflornithine and Uterine Neoplasms
| Article | Year |
|---|---|
The chemopreventive agents 4-HPR and DFMO inhibit growth and induce apoptosis in uterine leiomyomas.
Topics: Antineoplastic Agents; Apoptosis; Cell Division; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Depen | 2004 |
Ornithine decarboxylase activity in human endometrium and endometrial cancer cells.
Topics: Adenocarcinoma; Cell Division; Cell Line; Corpus Luteum; Cycloheximide; Dactinomycin; Eflornithine; | 1985 |