eflornithine has been researched along with Teratoma in 8 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Teratoma: A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schindler, J | 3 |
| Kelly, M | 3 |
| McCann, PP | 3 |
| Heby, O | 3 |
| Oredsson, SM | 3 |
| Kanje, M | 1 |
| Fleck, JF | 1 |
| Sledge, GW | 1 |
| Benenati, SV | 1 |
| Frolik, CA | 1 |
| Roth, BJ | 1 |
| Hirsch, KS | 1 |
| Wallon, M | 1 |
| Holm, I | 1 |
| Thorsson, L | 1 |
| Jetten, AM | 1 |
| Shirley, JE | 1 |
| Billgren, M | 1 |
8 other studies available for eflornithine and Teratoma
| Article | Year |
|---|---|
Inhibition of ornithine decarboxylase induces embryonal carcinoma cell differentiation.
Topics: Animals; Carboxy-Lyases; Cell Differentiation; Cell Line; Eflornithine; Mice; Neoplasms, Experimenta | 1983 |
Polyamine biosynthetic enzymes as targets in cancer chemotherapy.
Topics: Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; Cell Transformatio | 1984 |
Binding of insulin-like growth factors to Tera-2 human embryonal carcinoma cells during differentiation.
Topics: Binding Sites; Binding, Competitive; Cell Differentiation; Cell Division; Cell Line; DNA Replication | 1991 |
Residual proliferative capacity in F9 teratocarcinoma stem cell cultures treated with alpha-difluoromethylornithine, an inducer of parietal endoderm differentiation.
Topics: Cell Differentiation; Cell Division; Eflornithine; Embryonal Carcinoma Stem Cells; Endoderm; Humans; | 1990 |
Inhibition of ornithine decarboxylase by retinoic acid and difluoromethylornithine in relation to their effects on differentiation and proliferation.
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Cells, Cultured; Eflornithine; Fibroblasts; | 1985 |
The response of several murine embryonal carcinoma cell lines to stimulation of differentiation by alpha-difluoromethylornithine.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Line; Eflornithine; Embryo | 1985 |
Induction of F9 embryonal carcinoma cell differentiation by inhibition of polyamine synthesis.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chromat | 1985 |
Alterations in polyamine metabolism during embryonal carcinoma cell differentiation in vitro.
Topics: Animals; Cell Differentiation; Cell Line; Eflornithine; Kinetics; Mice; Ornithine; Ornithine Decarbo | 1985 |