eflornithine has been researched along with Stomach Ulcer in 10 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to determine the efficacy of L-arginine in healing of gastric ulcers induced by acetic acid and to assess the role of nitric oxide (NO), prostaglandins, gastrin and polyamines in the healing process." | 7.69 | Healing of chronic gastric ulcerations by L-arginine. Role of nitric oxide, prostaglandins, gastrin and polyamines. ( Brzozowski, T; Dembiński, A; Drozdowicz, D; Konturek, SJ; Stachura, J, 1995) |
| "This study was designed to determine the efficacy of L-arginine in healing of gastric ulcers induced by acetic acid and to assess the role of nitric oxide (NO), prostaglandins, gastrin and polyamines in the healing process." | 3.69 | Healing of chronic gastric ulcerations by L-arginine. Role of nitric oxide, prostaglandins, gastrin and polyamines. ( Brzozowski, T; Dembiński, A; Drozdowicz, D; Konturek, SJ; Stachura, J, 1995) |
| "Pretreatment with indomethacin, to suppress mucosal generation of prostaglandins (PG), greatly augmented stress-induced gastric ulcerations and antagonized the protection exerted by both Solcoseryl and EGF." | 1.28 | Solcoseryl in prevention of stress-induced gastric lesions and healing of chronic ulcers. ( Bielański, W; Brzozowski, T; Drozdowicz, D; Konturek, SJ; Pytko-Polonczyk, J, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (90.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Konturek, SJ | 6 |
| Brzozowski, T | 6 |
| Majka, I | 1 |
| Pawlik, W | 1 |
| Stachura, J | 2 |
| Wang, JY | 2 |
| Johnson, LR | 2 |
| Drozdowicz, D | 2 |
| Dembiński, A | 2 |
| Konturek, PC | 2 |
| Brzozowska, I | 1 |
| Kwiecien, S | 1 |
| Hahn, EG | 2 |
| Szlachcic, A | 1 |
| Ye, YN | 1 |
| Liu, ES | 1 |
| Shin, VY | 1 |
| Koo, MW | 1 |
| Li, Y | 1 |
| Wei, EQ | 1 |
| Matsui, H | 1 |
| Cho, CH | 1 |
| Marcuard, SP | 1 |
| Silverman, JF | 1 |
| Finley, JL | 1 |
| Seidel, ER | 1 |
| Pytko-Polonczyk, J | 1 |
| Bielański, W | 1 |
| Konturek, PK | 1 |
10 other studies available for eflornithine and Stomach Ulcer
| Article | Year |
|---|---|
Omentum and basic fibroblast growth factor in healing of chronic gastric ulcerations in rats.
Topics: Animals; Blood Flow Velocity; Chronic Disease; Dinoprostone; Eflornithine; Fibroblast Growth Factor | 1994 |
Expression of protooncogenes c-fos and c-myc in healing of gastric mucosal stress ulcers.
Topics: Animals; Blotting, Northern; Blotting, Western; DNA; DNA Probes; Eflornithine; Enzyme Induction; Gas | 1994 |
Healing of chronic gastric ulcerations by L-arginine. Role of nitric oxide, prostaglandins, gastrin and polyamines.
Topics: Animals; Arginine; Chronic Disease; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Efl | 1995 |
Involvement of ornithine decarboxylase and polyamines in epidermal growth factor-induced recovery of gastric mucosa from gastric lesions provoked by stress.
Topics: Animals; Anti-Ulcer Agents; Eflornithine; Enzyme Inhibitors; Epidermal Growth Factor; Gastric Mucosa | 1998 |
Polyamines and epidermal growth factor in the recovery of gastric mucosa from stress-induced gastric lesions.
Topics: Animals; Eflornithine; Enzyme Inhibitors; Epidermal Growth Factor; Gastric Mucosa; Male; Ornithine D | 1998 |
A mechanistic study of proliferation induced by Angelica sinensis in a normal gastric epithelial cell line.
Topics: Angelica sinensis; Animals; Apiaceae; Cell Division; Cells, Cultured; Disease Models, Animal; DNA; D | 2001 |
Ornithine decarboxylase activity during gastric ulcer healing in dogs.
Topics: Animals; Dogs; Eflornithine; Gastric Mucosa; Ornithine Decarboxylase; Polyamines; Stomach Ulcer; Tim | 1992 |
Luminal polyamines stimulate repair of gastric mucosal stress ulcers.
Topics: Animals; DNA; Eflornithine; Gastric Mucosa; Male; Ornithine Decarboxylase; Parietal Cells, Gastric; | 1990 |
Solcoseryl in prevention of stress-induced gastric lesions and healing of chronic ulcers.
Topics: Actihaemyl; Analysis of Variance; Animals; Dinoprostone; Eflornithine; Epidermal Growth Factor; Gast | 1991 |
Role of epidermal growth factor, prostaglandin, and sulfhydryls in stress-induced gastric lesions.
Topics: 16,16-Dimethylprostaglandin E2; Animals; DNA; Eflornithine; Epidermal Growth Factor; Ethylmaleimide; | 1990 |