eflornithine has been researched along with Pulmonary Fibrosis in 2 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giri, SN | 1 |
| Hyde, DM | 1 |
| Schwartz, LW | 1 |
| Younker, WR | 1 |
| Frost, SB | 1 |
| Rakieten, N | 1 |
| Raisfeld-Danse, IH | 1 |
2 other studies available for eflornithine and Pulmonary Fibrosis
| Article | Year |
|---|---|
The effect of alpha-difluoromethylornithine on the development of bleomycin-induced pulmonary fibrosis in hamsters.
Topics: Animals; Bleomycin; Collagen; Cricetinae; Eflornithine; Lung; Mesocricetus; Ornithine; Pulmonary Fib | 1982 |
Studies of the effects of alpha-difluoromethylornithine and ethanol on the pathogenesis of bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Eflornithine; Ethanol; Fibroblasts; Lung; Male; Mice; Mice, Inbred DBA; Microsom | 1983 |