eflornithine has been researched along with Muscle Contraction in 5 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These studies indicate that normalization of vascular function can occur in the presence of significantly elevated blood pressure upon chronic administration of eflornithine." | 5.30 | Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension. ( Aziz, SM; Lipke, DW; Newman, PS; Soltis, EE; Tofiq, S, 1997) |
| " These studies indicate that normalization of vascular function can occur in the presence of significantly elevated blood pressure upon chronic administration of eflornithine." | 1.30 | Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension. ( Aziz, SM; Lipke, DW; Newman, PS; Soltis, EE; Tofiq, S, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grossi, M | 1 |
| Persson, L | 1 |
| Swärd, K | 2 |
| Turczyńska, KM | 1 |
| Forte, A | 1 |
| Hellstrand, P | 1 |
| Nilsson, BO | 2 |
| Lorenzen, JM | 1 |
| Ückert, S | 1 |
| Scheller, F | 1 |
| Haller, H | 1 |
| Kuczyk, MA | 1 |
| Lipke, DW | 1 |
| Newman, PS | 1 |
| Tofiq, S | 1 |
| Aziz, SM | 1 |
| Soltis, EE | 1 |
| Lindqvist, A | 1 |
| Pandita, RK | 1 |
| Persson, K | 1 |
| Thyberg, J | 1 |
| Fredholm, BB | 1 |
5 other studies available for eflornithine and Muscle Contraction
| Article | Year |
|---|---|
Inhibition of polyamine formation antagonizes vascular smooth muscle cell proliferation and preserves the contractile phenotype.
Topics: Animals; Cattle; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Eflornithine | 2014 |
Effects of arginase inhibitors on the contractile and relaxant responses of isolated human penile erectile tissue.
Topics: Adult; Arginase; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Eflornithine; Enzyme Inhibi | 2009 |
Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension.
Topics: Acetylcholine; Animals; Aorta; Aortic Coarctation; Eflornithine; Enzyme Inhibitors; Hypertension; Mu | 1997 |
Effects of polyamine synthesis inhibition on polyamines, growth and mechanical properties in hypertrophic rat urinary bladder.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Biogenic Polyamines; Calcium; Eflornithine; Enz | 1998 |
Modulation of arterial smooth muscle cells from contractile to synthetic phenotype requires induction of ornithine decarboxylase activity and polyamine synthesis.
Topics: Animals; Aorta; Cell Division; Cells, Cultured; Eflornithine; Enzyme Induction; Male; Muscle Contrac | 1987 |