eflornithine has been researched along with Mesothelioma in 1 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Mesothelioma: A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant mesothelioma is an aggressive tumor, usually induced by asbestos exposure, that has a poor prognosis and is unresponsive to conventional therapy." | 1.29 | Potential for interferon-alpha-based therapy in mesothelioma: assessment in a murine model. ( Bielefeldt-Ohmann, H; Fitzpatrick, DR; Jarnicki, AG; Marzo, AL; Musk, AW; Robinson, BW, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bielefeldt-Ohmann, H | 1 |
| Fitzpatrick, DR | 1 |
| Marzo, AL | 1 |
| Jarnicki, AG | 1 |
| Musk, AW | 1 |
| Robinson, BW | 1 |
1 other study available for eflornithine and Mesothelioma
| Article | Year |
|---|---|
Potential for interferon-alpha-based therapy in mesothelioma: assessment in a murine model.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Combined Chemotherapy Protocols; beta Carotene; Caro | 1995 |