eflornithine has been researched along with Medulloblastoma in 2 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Medulloblastoma: A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deen, DF | 1 |
| Chiarodo, A | 1 |
| Grimm, EA | 1 |
| Fike, JR | 1 |
| Israel, MA | 1 |
| Kun, LE | 1 |
| Levin, VA | 2 |
| Marton, LJ | 1 |
| Packer, RJ | 1 |
| Pegg, AE | 1 |
1 review available for eflornithine and Medulloblastoma
| Article | Year |
|---|---|
Chemotherapy of primary brain tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Efl | 1985 |
1 other study available for eflornithine and Medulloblastoma
| Article | Year |
|---|---|
Brain Tumor Working Group Report on the 9th International Conference on Brain Tumor Research and Therapy. Organ System Program, National Cancer Institute.
Topics: Adult; Animals; Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Clinical Trials as | 1993 |