eflornithine has been researched along with Lupus Nephritis in 2 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Lupus Nephritis: Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsu, HC | 1 |
| Thomas, T | 1 |
| Seibold, JR | 2 |
| Thomas, TJ | 2 |
| Gunnia, UB | 1 |
| Amenta, PS | 1 |
2 other studies available for eflornithine and Lupus Nephritis
| Article | Year |
|---|---|
Studies on the effects of an ornithine decarboxylase inhibitor on lupus nephritis reveal a post-transcriptional modification of the enzyme.
Topics: Animals; Blotting, Northern; Eflornithine; Female; Kidney; Lupus Nephritis; Mice; Mice, Inbred BALB | 1993 |
Successful treatment of lupus nephritis in MRL-lpr/lpr mice by inhibiting ornithine decarboxylase.
Topics: Animals; Antibodies, Antinuclear; Disease Models, Animal; Dose-Response Relationship, Drug; Eflornit | 1991 |