eflornithine has been researched along with Lung Neoplasms in 49 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have investigated effects of alpha-difluoromethylornithine (DFMO), both as a single agent and in combination with 5-fluorouracil (5-FU) against a human colon tumor xenograft (T6) grown as primary tissue culture in serum-free medium and in combination with doxorubicin (DX) against a human lung adenocarcinoma cell line (A549)." | 7.68 | In vitro response of a human colon tumor xenograft and a lung adenocarcinoma cell line to alpha-difluoromethylornithine alone and in combination with 5-fluorouracil and doxorubicin. ( Atabek, U; Zirvi, KA, 1991) |
| "The depletion of polyamines by alpha-difluoromethylornithine (DFMO) treatment of mice after subcutaneous inoculation of adenocarcinoma M3 cells caused a remarkable inhibition in the growth rate of primary tumors as well as in the occurrence and number of lung metastases with a concomitant increase in survival time." | 7.67 | Effect of alpha-difluoromethylornithine in lung metastases before and after surgery of primary adenocarcinoma tumors in mice. ( Algranati, ID; de Lustig, ES; Klein, S; Miret, JJ, 1985) |
| "We have investigated effects of alpha-difluoromethylornithine (DFMO), both as a single agent and in combination with 5-fluorouracil (5-FU) against a human colon tumor xenograft (T6) grown as primary tissue culture in serum-free medium and in combination with doxorubicin (DX) against a human lung adenocarcinoma cell line (A549)." | 3.68 | In vitro response of a human colon tumor xenograft and a lung adenocarcinoma cell line to alpha-difluoromethylornithine alone and in combination with 5-fluorouracil and doxorubicin. ( Atabek, U; Zirvi, KA, 1991) |
| " Small cell lung carcinoma cells die following polyamine depletion by difluoromethylornithine treatment while non-small cell lines demonstrate a typical cytostatic response." | 3.67 | Human lung tumor sensitivity to difluoromethylornithine as related to ornithine decarboxylase messenger RNA levels. ( Baylin, SB; Casero, RA; Luk, GD; Nelkin, BD, 1986) |
| "The depletion of polyamines by alpha-difluoromethylornithine (DFMO) treatment of mice after subcutaneous inoculation of adenocarcinoma M3 cells caused a remarkable inhibition in the growth rate of primary tumors as well as in the occurrence and number of lung metastases with a concomitant increase in survival time." | 3.67 | Effect of alpha-difluoromethylornithine in lung metastases before and after surgery of primary adenocarcinoma tumors in mice. ( Algranati, ID; de Lustig, ES; Klein, S; Miret, JJ, 1985) |
| "DFMO did not affect pulmonary metastasis when primary tumors of control and DFMO-treated mice were matched for size." | 1.35 | Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells. ( Bruggeman, R; Demers, LM; Griffith, JW; Jun, JY; Manni, A; Verderame, MF; Washington, S, 2008) |
| "The number and incidence of lung metastases were determined." | 1.33 | Metastasis of hormone-independent breast cancer to lung and bone is decreased by alpha-difluoromethylornithine treatment. ( Bond, JS; Demers, LM; DiGirolamo, DJ; Manni, A; Matters, G; Phadke, PA; Richert, MM; Washington, S; Welch, DR, 2005) |
| "Infiltrating squamous cell carcinomas of the URT occurred in 92% of the controls and were reduced by 50% in animals receiving DFMO (P = 0." | 1.32 | Chemoprevention of cancer of the upper respiratory tract of the Syrian golden hamster by aerosol administration of difluoromethylornithine and 5-fluorouracil. ( Estensen, RD; Wattenberg, LW; Wiedmann, TS, 2004) |
| "Human lung squamous carcinoma cells L78 treated with 5 mmol/L alpha-difluoromethylornithine (DFMO) for 5 days showed significant growth inhibition and apoptosis induction." | 1.31 | [Effect of alpha-difluoromethylornithine on growth characteristics and expression of ALT-04ag gene of human lung carcinoma cells]. ( Cao, SL; Chen, ZH; Fan, MZ; Fang, Q; Ke, HP; Li, HY, 2002) |
| "The formation of lung metastases was prevented by 70 to 100%, depending on the treatment." | 1.28 | Endogenous and exogenous polyamines in support of tumor growth. ( Grauffel, C; Jones, R; Knödgen, B; Moulinoux, JP; Sarhan, S; Seiler, N, 1990) |
| "Treatment of mice bearing B16 melanoma with DFMO resulted in 81% inhibition of tumor growth compared to controls." | 1.28 | Effect of murine alpha-, beta-, and gamma-interferons in combination with alpha-difluoromethylornithine, an inhibitor of polyamine biosynthesis, on the tumor growth and metastasis of B16 melanoma and Lewis lung carcinoma in mice. ( Bowlin, TL; Fleischmann, WR; Rosenberger, AL; Sunkara, PS, 1989) |
| "When tilorone was given 7 days after tumor inoculation, it did not show any potentiation of antitumor activity of DFMO." | 1.27 | Potentiation of antitumor and antimetastatic activities of alpha-difluoromethylornithine by interferon inducers. ( Hagan, AC; Lachmann, PJ; Mayer, GD; Prakash, NJ; Rosenberger, AL; Sunkara, PS, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (51.02) | 18.7374 |
| 1990's | 11 (22.45) | 18.2507 |
| 2000's | 11 (22.45) | 29.6817 |
| 2010's | 1 (2.04) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Lam, SK | 1 |
| Yan, S | 1 |
| Xu, S | 1 |
| Ho, JC | 1 |
| Samoilenko, ОА | 1 |
| Milinevska, OA | 1 |
| Karnaushenko, OV | 1 |
| Shlyakhovenko, VA | 1 |
| Zaletok, SP | 1 |
| Anderson, MW | 2 |
| Goodin, C | 1 |
| Zhang, Y | 2 |
| Kim, S | 1 |
| Estensen, RD | 2 |
| Wiedmann, TS | 2 |
| Sekar, P | 1 |
| Buncher, CR | 1 |
| Khoury, JC | 1 |
| Garbow, JR | 1 |
| You, M | 1 |
| Tichelaar, JW | 2 |
| Manni, A | 5 |
| Washington, S | 5 |
| Craig, L | 1 |
| Cloud, M | 1 |
| Griffith, JW | 4 |
| Verderame, MF | 4 |
| Texter, LJ | 1 |
| Mauger, D | 3 |
| Demers, LM | 5 |
| Harms, JF | 1 |
| Welch, DR | 3 |
| Chen, ZH | 1 |
| Ke, HP | 1 |
| Li, HY | 1 |
| Fang, Q | 1 |
| Cao, SL | 1 |
| Fan, MZ | 2 |
| Xiang, Q | 1 |
| Xu, B | 1 |
| Wattenberg, LW | 1 |
| LeRiche, JC | 1 |
| Lam, S | 1 |
| Hu, X | 1 |
| Bruggeman, R | 2 |
| Richert, MM | 1 |
| Phadke, PA | 1 |
| Matters, G | 1 |
| DiGirolamo, DJ | 1 |
| Bond, JS | 1 |
| Jun, JY | 1 |
| Warrell, RP | 1 |
| Burchenal, JH | 1 |
| Luk, GD | 9 |
| Goodwin, G | 2 |
| Marton, LJ | 1 |
| Baylin, SB | 10 |
| Bartholeyns, J | 2 |
| Abeloff, MD | 3 |
| Griffin, CA | 1 |
| Sunkara, PS | 4 |
| Prakash, NJ | 2 |
| Rosenberger, AL | 4 |
| Hagan, AC | 1 |
| Lachmann, PJ | 1 |
| Mayer, GD | 1 |
| Mamont, P | 1 |
| Casara, P | 1 |
| Gazdar, AF | 2 |
| Gerner, EW | 1 |
| Kurtts, TA | 1 |
| Fuller, DJ | 1 |
| Casero, RA | 6 |
| Shao, D | 1 |
| Xiao, L | 1 |
| Ha, HC | 1 |
| Cipolla, B | 1 |
| Blanchard, Y | 1 |
| Chamaillard, L | 1 |
| Quemener, V | 1 |
| Guillé, F | 1 |
| Havouis, R | 1 |
| Moulinoux, JP | 2 |
| Boone, CW | 1 |
| Steele, VE | 2 |
| Gaylor, D | 1 |
| Kelloff, GJ | 1 |
| Sun, SY | 1 |
| Yue, P | 1 |
| Shroot, B | 1 |
| Hong, WK | 1 |
| Lotan, R | 1 |
| Gunning, WT | 1 |
| Kramer, PM | 1 |
| Lubet, RA | 1 |
| Pereira, MA | 1 |
| Samant, RS | 1 |
| Twentyman, PR | 1 |
| Wright, KA | 1 |
| Wallace, HM | 1 |
| Zirvi, KA | 1 |
| Atabek, U | 1 |
| Hessels, J | 1 |
| Kingma, AW | 1 |
| Muskiet, FA | 1 |
| Sarhan, S | 3 |
| Seiler, N | 3 |
| Grauffel, C | 1 |
| Jones, R | 1 |
| Knödgen, B | 2 |
| Falco, JP | 1 |
| Lupu, R | 1 |
| Borges, M | 1 |
| Nelkin, BD | 3 |
| Jasti, RK | 1 |
| Davidson, NE | 1 |
| Mabry, M | 2 |
| Roizin-Towle, L | 1 |
| Yarlett, N | 1 |
| Pirro, JP | 1 |
| Delohery, TM | 1 |
| Bowlin, TL | 1 |
| Fleischmann, WR | 1 |
| Claverie, N | 1 |
| Mamont, PS | 1 |
| Denstman, SC | 1 |
| Ervin, SJ | 1 |
| Tsai, DC | 1 |
| Nakagawa, T | 1 |
| McDowell, E | 1 |
| Gesell, M | 1 |
| Eggleston, JC | 1 |
| McCann, PP | 1 |
| Sjoerdsma, A | 2 |
| Rosen, ST | 1 |
| Zeltzman, M | 1 |
| Go, B | 1 |
| Theiss, HW | 1 |
| Smith, J | 1 |
| Bepler, G | 1 |
| Carney, DN | 1 |
| Nau, MM | 1 |
| Minna, JD | 1 |
| Kubota, S | 1 |
| Ohsawa, N | 1 |
| Takaku, F | 1 |
| Niederkorn, JY | 1 |
| Sanborn, GE | 1 |
| Gamel, JW | 1 |
| Gerhart, F | 1 |
| Nakaike, S | 1 |
| Kashiwagi, K | 1 |
| Terao, K | 1 |
| Iio, K | 1 |
| Igarashi, K | 1 |
| Klein, S | 1 |
| Miret, JJ | 1 |
| Algranati, ID | 1 |
| de Lustig, ES | 1 |
1 review available for eflornithine and Lung Neoplasms
| Article | Year |
|---|---|
Methylglyoxal-bis(guanylhydrazone) (Methyl-GAG): current status and future prospects.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Tri | 1983 |
1 trial available for eflornithine and Lung Neoplasms
| Article | Year |
|---|---|
Methylglyoxal-bis(guanylhydrazone) (Methyl-GAG): current status and future prospects.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Tri | 1983 |
48 other studies available for eflornithine and Lung Neoplasms
| Article | Year |
|---|---|
Targeting polyamine as a novel therapy in xenograft models of malignant pleural mesothelioma.
Topics: Animals; Eflornithine; Heterografts; Lung Neoplasms; Mesothelioma, Malignant; Mice; Mice, Nude; Poly | 2020 |
Effect of polyamine metabolism inhibitors on Lewis lung carcinoma growth and metastasis.
Topics: Animals; Arginase; Arginine; Carcinoma, Lewis Lung; Cell Line, Tumor; Drug Screening Assays, Antitum | 2015 |
Effect of dietary green tea extract and aerosolized difluoromethylornithine during lung tumor progression in A/J strain mice.
Topics: Aerosols; Animals; Antineoplastic Agents; Chemoprevention; Disease Progression; Eflornithine; Female | 2008 |
Effects of alpha-difluoromethylornithine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice.
Topics: Animals; Eflornithine; Enzyme Inhibitors; Female; Green Fluorescent Proteins; Humans; Luminescent Pr | 2003 |
[Effect of alpha-difluoromethylornithine on growth characteristics and expression of ALT-04ag gene of human lung carcinoma cells].
Topics: Antigens, Neoplasm; Apoptosis; Carcinoma, Squamous Cell; Cell Division; Down-Regulation; Eflornithin | 2002 |
[Apoptotic induction of human lung carcinoma A549 cells by DFMO through Fas/FasL pathway].
Topics: Antineoplastic Agents; Apoptosis; Cell Division; Eflornithine; Fas Ligand Protein; fas Receptor; Hum | 2003 |
Chemoprevention of cancer of the upper respiratory tract of the Syrian golden hamster by aerosol administration of difluoromethylornithine and 5-fluorouracil.
Topics: Administration, Inhalation; Aerosols; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Squa | 2004 |
Activation of the Akt/nuclear factor-kappaB signaling axis in developing lung neoplasia.
Topics: Anticarcinogenic Agents; Budesonide; Catechin; Cell Line, Tumor; Eflornithine; Humans; Lung Neoplasm | 2004 |
Effects of polyamine synthesis inhibitors on primary tumor features and metastatic capacity of human breast cancer cells.
Topics: Amidines; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proli | 2005 |
Metastasis of hormone-independent breast cancer to lung and bone is decreased by alpha-difluoromethylornithine treatment.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Eflornithine; Fe | 2005 |
Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Eflornithine; Extracellular Signal-Regulated MAP Kina | 2008 |
Polyamines are necessary for the survival of human small-cell lung carcinoma in culture.
Topics: Carcinoma, Small Cell; Cell Aggregation; Cell Division; Cell Survival; Cells, Cultured; Eflornithine | 1981 |
Treatment of metastatic Lewis lung carcinoma with DL-alpha-difluoromethylornithine.
Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Eflornithine; Female; Lung; Lung N | 1983 |
Successful treatment with DL-alpha-difluoromethylornithine in established human small cell variant lung carcinoma implants in athymic mice.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line; Drug Evaluation, Preclinical; Eflornithine; | 1983 |
Potentiation of antitumor and antimetastatic activities of alpha-difluoromethylornithine by interferon inducers.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Drug Synergism; Eflornithine; Fluorenes; L | 1984 |
Antitumor properties of (2R,5R)-6-heptyne-2,5-diamine, a new potent enzyme-activated irreversible inhibitor of ornithine decarboxylase, in rodents.
Topics: Alkynes; Animals; Antineoplastic Agents; Diamines; Dose-Response Relationship, Drug; Drug Evaluation | 1984 |
Growth-inhibitory effects of DL-alpha-difluoromethylornithine in the spectrum of human lung carcinoma cells in culture.
Topics: Antineoplastic Agents; Cell Division; Cell Line; Drug Evaluation, Preclinical; Eflornithine; Humans; | 1982 |
An essential role for polyamines in tumor metastases.
Topics: Animals; Antineoplastic Agents; Cell Division; Eflornithine; Lung Neoplasms; Mice; Mice, Inbred C57B | 1982 |
Stress induction of the spermidine/spermine N1-acetyltransferase by a post-transcriptional mechanism in mammalian cells.
Topics: Acetylation; Acetyltransferases; Animals; CHO Cells; Cricetinae; Ditiocarb; Eflornithine; Enzyme Ind | 1993 |
Isolation of a polyamine transport deficient cell line from the human non-small cell lung carcinoma line NCI H157.
Topics: Acetyltransferases; Antineoplastic Agents; Biological Transport; Carcinoma, Non-Small-Cell Lung; Cel | 1996 |
In vivo, synergestic inhibition of MAT-LyLu rat prostatic adenocarcinoma growth by polyamine deprivation and low-dose cyclophosphamide.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Co | 1996 |
Use of Druckrey analysis to quantitatively evaluate the chemopreventive efficacy of N-difluoromethylornithine (DFMO), a prototype proliferation inhibitor.
Topics: Animals; Anticarcinogenic Agents; Cell Division; Cell Transformation, Neoplastic; Eflornithine; Fema | 1998 |
Implication of c-Myc in apoptosis induced by the retinoid CD437 in human lung carcinoma cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Carcinoma, Non-Small-Cell Lung; cdc25 Phosphatases; Cyst | 1999 |
Chemoprevention of vinyl carbamate-induced lung tumors in strain A mice.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Chemoprevention; Dexamethaso | 2000 |
Influence of polyamines on in vitro and in vivo features of aggressive and metastatic behavior by human breast cancer cells.
Topics: Animals; Biogenic Polyamines; Blotting, Northern; Breast Neoplasms; Collagen; Dose-Response Relation | 2002 |
Effects of cyclosporin A and a non-immunosuppressive analogue, O-acetyl cyclosporin A, upon the growth of parent and multidrug resistant human lung cancer cells in vitro.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Cell Line; Cel | 1992 |
In vitro response of a human colon tumor xenograft and a lung adenocarcinoma cell line to alpha-difluoromethylornithine alone and in combination with 5-fluorouracil and doxorubicin.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Colonic Neoplasms; Do | 1991 |
Growth inhibition of two solid tumors in mice, caused by polyamine depletion, is not attended by alterations in cell-cycle phase distribution.
Topics: Animals; Cell Cycle; Cell Division; Eflornithine; Female; Fibrosarcoma; Kinetics; Lung Neoplasms; Mi | 1991 |
Endogenous and exogenous polyamines in support of tumor growth.
Topics: Animals; Antineoplastic Agents; Cell Division; Eflornithine; Female; Leukocyte Count; Lung Neoplasms | 1990 |
v-rasH induces non-small cell phenotype, with associated growth factors and receptors, in a small cell lung cancer cell line.
Topics: Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Eflornithine; Epidermal Growth | 1990 |
Hyperthermia studies in polyamine-altered human lung carcinoma cells.
Topics: Acclimatization; Cell Line; Cell Survival; Eflornithine; Hot Temperature; Humans; In Vitro Technique | 1990 |
Effect of murine alpha-, beta-, and gamma-interferons in combination with alpha-difluoromethylornithine, an inhibitor of polyamine biosynthesis, on the tumor growth and metastasis of B16 melanoma and Lewis lung carcinoma in mice.
Topics: Animals; Drug Synergism; Eflornithine; Interferon Type I; Interferon-gamma; Lung Neoplasms; Melanoma | 1989 |
Comparative antitumor properties in rodents of irreversible inhibitors of L-ornithine decarboxylase, used as such or as prodrugs.
Topics: Administration, Oral; Alkynes; Animals; Diamines; Eflornithine; Injections, Intraperitoneal; Leukemi | 1989 |
Comparison of the effects of treatment with the polyamine analogue N1,N8 bis(ethyl)spermidine (BESpd) or difluoromethylornithine (DFMO) on the Topoisomerase II mediated formation of 4'-(9-acridinylamino) methanesulfon-m-anisidide (m-AMSA) induced cleavabl
Topics: Amsacrine; Chemical Precipitation; DNA Topoisomerases, Type II; DNA, Neoplasm; Eflornithine; Humans; | 1987 |
The growth-inhibitory effect of 4-hydroperoxycyclophosphamide against human non-small cell lung carcinoma is enhanced by low-dose difluoromethylornithine.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cyclophosphamide; Dose-Response Relationship, Drug; Drug | 1988 |
v-Ha-ras oncogene insertion: a model for tumor progression of human small cell lung cancer.
Topics: Carcinoembryonic Antigen; Carcinoma, Small Cell; Cell Division; Cell Line; Clone Cells; DNA Transpos | 1988 |
Human lung tumor sensitivity to difluoromethylornithine as related to ornithine decarboxylase messenger RNA levels.
Topics: Carcinoma; Carcinoma, Small Cell; Cell Cycle; Cells, Cultured; Eflornithine; Humans; Lung Neoplasms; | 1986 |
Anchorage dependency effects on difluoromethylornithine cytotoxicity in human lung carcinoma cells.
Topics: Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Aggregation; Cell Communication; Cell Survival | 1986 |
Long-term maintenance therapy of established human small cell variant lung carcinoma implants in athymic mice with a cyclic regimen of difluoromethylornithine.
Topics: Animals; Body Weight; Carcinoma, Small Cell; Cell Aggregation; Eflornithine; Female; Lung Neoplasms; | 1986 |
Phase II trials of alpha-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer.
Topics: Aged; Antineoplastic Agents; Carcinoma, Small Cell; Colonic Neoplasms; Drug Evaluation; Eflornithine | 1986 |
Cytotoxic response of the relatively difluoromethylornithine-resistant human lung tumor cell line NCI H157 to the polyamine analogue N1,N8-bis(ethyl)spermidine.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, | 1987 |
Additive and differential biological activity of alpha-interferon A, difluoromethylornithine, and their combination on established human lung cancer cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Line; Dopa Decarboxylase; Dose-Resp | 1986 |
Antimetastatic activity of DL-alpha-difluoromethylornithine, an inhibitor of polyamine biosynthesis, in mice.
Topics: Animals; Eflornithine; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neop | 1987 |
Effects of DL-alpha-difluoromethylornithine on the growth and metastasis of B16 melanoma in vivo.
Topics: Animals; Eflornithine; Female; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Polyamines | 1987 |
Suicide enzyme inhibition as a chemotherapeutic strategy for controlling metastases derived from intraocular melanomas.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Eflornithine; Enzyme Inhibitor | 1987 |
Chain-fluorinated polyamines as tumor markers--I. In vivo transformation of 2,2-difluoroputrescine into 6,6-difluorospermidine and 6,6-difluorospermine.
Topics: Animals; Biomarkers, Tumor; Biotransformation; Cattle; Cell Division; Eflornithine; Female; Liver Ne | 1987 |
Combined use of alpha-difluoromethylornithine and an inhibitor of S-adenosylmethionine decarboxylase in mice bearing P388 leukemia or Lewis lung carcinoma.
Topics: Adenosylmethionine Decarboxylase; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined | 1988 |
Effect of alpha-difluoromethylornithine in lung metastases before and after surgery of primary adenocarcinoma tumors in mice.
Topics: Adenocarcinoma; Animals; Eflornithine; Lung; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; | 1985 |