eflornithine has been researched along with Leukemia P388 in 6 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Leukemia P388: An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chandar, N | 1 |
| Nagarajan, B | 1 |
| Bartholeyns, J | 1 |
| Mamont, P | 1 |
| Casara, P | 1 |
| He, Y | 1 |
| Shimogori, T | 1 |
| Kashiwagi, K | 2 |
| Shirahata, A | 1 |
| Igarashi, K | 2 |
| Kremmer, T | 2 |
| Boldizsár, M | 2 |
| Holczinger, L | 2 |
| Nakaike, S | 1 |
| Terao, K | 1 |
| Iio, K | 1 |
| Pályi, I | 1 |
| Lörincz, I | 1 |
| Paulik, E | 1 |
| Pokorny, E | 1 |
6 other studies available for eflornithine and Leukemia P388
| Article | Year |
|---|---|
Host liver changes in leukemic mice: effect of alpha-difluoromethyl ornithine, an inhibitor of polyamine synthesis.
Topics: Animals; beta-N-Acetylhexosaminidases; Eflornithine; Female; gamma-Glutamyltransferase; Glutathione; | 1984 |
Antitumor properties of (2R,5R)-6-heptyne-2,5-diamine, a new potent enzyme-activated irreversible inhibitor of ornithine decarboxylase, in rodents.
Topics: Alkynes; Animals; Antineoplastic Agents; Diamines; Dose-Response Relationship, Drug; Drug Evaluation | 1984 |
Inhibition of cell growth by combination of alpha-difluoromethylornithine and an inhibitor of spermine synthase.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cyclohexylamines; Drug Syner | 1995 |
In vivo effects of DL-alpha-difluoromethylornithine on the polyamine and nucleotide phosphate metabolism in P388/S leukemia cells.
Topics: Animals; Cell Line; Eflornithine; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred St | 1986 |
Combined use of alpha-difluoromethylornithine and an inhibitor of S-adenosylmethionine decarboxylase in mice bearing P388 leukemia or Lewis lung carcinoma.
Topics: Adenosylmethionine Decarboxylase; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined | 1988 |
Changes in the polyamine and nucleotide metabolism of P388 leukemia cells treated with DL-alpha-difluoromethylornithine in culture.
Topics: Animals; Dose-Response Relationship, Drug; Eflornithine; Leukemia P388; Leukemia, Experimental; Mice | 1988 |