eflornithine has been researched along with Innate Inflammatory Response in 5 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Up-regulation of arginase contributes to airways hyperresponsiveness (AHR) in asthma by reducing L-arginine bioavailability for the nitric oxide (NO) synthase isozymes." | 5.39 | Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma. ( Gauvreau, GM; Grasemann, H; Inman, MD; Khanna, N; North, ML; Scott, JA, 2013) |
| "Up-regulation of arginase contributes to airways hyperresponsiveness (AHR) in asthma by reducing L-arginine bioavailability for the nitric oxide (NO) synthase isozymes." | 1.39 | Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma. ( Gauvreau, GM; Grasemann, H; Inman, MD; Khanna, N; North, ML; Scott, JA, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| North, ML | 1 |
| Grasemann, H | 1 |
| Khanna, N | 1 |
| Inman, MD | 1 |
| Gauvreau, GM | 1 |
| Scott, JA | 1 |
| Rial, NS | 1 |
| Meyskens, FL | 1 |
| Gerner, EW | 1 |
| Silva, MA | 1 |
| Klafke, JZ | 1 |
| Rossato, MF | 1 |
| Gewehr, C | 1 |
| Guerra, GP | 1 |
| Rubin, MA | 1 |
| Ferreira, J | 1 |
| Chen, X | 1 |
| Li, N | 1 |
| Wang, S | 1 |
| Hong, J | 1 |
| Fang, M | 1 |
| Yousselfson, J | 1 |
| Yang, P | 1 |
| Newman, RA | 1 |
| Lubet, RA | 1 |
| Yang, CS | 1 |
| Tjandrawinata, RR | 1 |
| Hawel, L | 1 |
| Byus, CV | 1 |
1 review available for eflornithine and Innate Inflammatory Response
| Article | Year |
|---|---|
Polyamines as mediators of APC-dependent intestinal carcinogenesis and cancer chemoprevention.
Topics: Adenomatous Polyposis Coli Protein; Animals; Clinical Trials as Topic; Eflornithine; Genetic Predisp | 2009 |
4 other studies available for eflornithine and Innate Inflammatory Response
| Article | Year |
|---|---|
Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma.
Topics: Adolescent; Adult; Animals; Asthma; Disease Models, Animal; Eflornithine; Female; Humans; Hypersensi | 2013 |
Role of peripheral polyamines in the development of inflammatory pain.
Topics: Animals; Eflornithine; Gene Expression Regulation, Enzymologic; Indoles; Inflammation; Male; Maleimi | 2011 |
Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Body Weight; Cyclooxygenase 2 | 2002 |
Regulation of putrescine export in lipopolysaccharide or IFN-gamma-activated murine monocytic-leukemic RAW 264 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; DNA; Dose-Response Relationship, Drug; Eflornithine | 1994 |