Page last updated: 2024-10-25

eflornithine and Hypertrichosis

eflornithine has been researched along with Hypertrichosis in 5 studies

Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.

Hypertrichosis: Excessive hair growth at inappropriate locations, such as on the extremities, the head, and the back. It is caused by genetic or acquired factors, and is an androgen-independent process. This concept does not include HIRSUTISM which is an androgen-dependent excess hair growth in WOMEN and CHILDREN.

Research Excerpts

ExcerptRelevanceReference
" No serious adverse events were reported during the studies, and the only adverse events considered related to treatment were pruritus (three subjects) and dry skin at test site (one subject)."2.70Human dermal safety studies with eflornithine HCl 13.9% cream (Vaniqa), a novel treatment for excessive facial hair. ( Hickman, JG; Huber, F; Palmisano, M, 2001)
"Hirsutism is defined as the excessive growth of terminal hair on the face and body of a female in a typical male pattern distribution."2.44Hirsutism. ( Mofid, A; Seyyed Alinaghi, SA; Yazdani, T; Zandieh, S, 2008)
"A new topical treatment of hypertrichosis is eflornithine cream."2.41[Current treatment of hypertrichosis]. ( Kunte, C; Wolff, H, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Barbareschi, M1
Benetti, F1
Gaio, E1
Angileri, L1
Veraldi, S1
Valejo Coelho, MM1
Carvalho, R1
Mofid, A1
Seyyed Alinaghi, SA1
Zandieh, S1
Yazdani, T1
Hickman, JG1
Huber, F1
Palmisano, M1
Kunte, C1
Wolff, H1

Reviews

2 reviews available for eflornithine and Hypertrichosis

ArticleYear
Hirsutism.
    International journal of clinical practice, 2008, Volume: 62, Issue:3

    Topics: Diagnosis, Differential; Eflornithine; Enzyme Inhibitors; Female; Hair Removal; Hirsutism; Humans; H

2008
[Current treatment of hypertrichosis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2001, Volume: 52, Issue:11

    Topics: Eflornithine; Electrolysis; Enzyme Inhibitors; Female; Hair Removal; Hirsutism; Humans; Hypertrichos

2001

Trials

2 trials available for eflornithine and Hypertrichosis

ArticleYear
Capryloyl glycine and soy isoflavonoids in hypertrichosis: An experimental and placebo-controlled clinical study.
    Journal of cosmetic dermatology, 2021, Volume: 20 Suppl 1

    Topics: Adult; Eflornithine; Female; Glycine; Hair Removal; Humans; Hypertrichosis; Skin

2021
Human dermal safety studies with eflornithine HCl 13.9% cream (Vaniqa), a novel treatment for excessive facial hair.
    Current medical research and opinion, 2001, Volume: 16, Issue:4

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Dermatitis, Photoallergic; De

2001

Other Studies

1 other study available for eflornithine and Hypertrichosis

ArticleYear
Use of Eflornithine Hydrochloride Cream to Reduce Facial Hair Growth in Flapped Skin.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2019, Volume: 45, Issue:12

    Topics: Aged; Carcinoma, Basal Cell; Dermoscopy; Eflornithine; Esthetics; Female; Forehead; Hair; Humans; Hy

2019