eflornithine has been researched along with Heart Diseases in 3 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cetrullo, S | 1 |
| Facchini, A | 1 |
| Stanic, I | 1 |
| Tantini, B | 1 |
| Pignatti, C | 1 |
| Caldarera, CM | 1 |
| Flamigni, F | 1 |
| Blum, JA | 1 |
| Burri, C | 1 |
| Hatz, C | 1 |
| Kazumba, L | 1 |
| Mangoni, P | 1 |
| Zellweger, MJ | 1 |
| Koenig, H | 1 |
| Goldstone, AD | 1 |
| Trout, JJ | 1 |
| Lu, CY | 1 |
1 trial available for eflornithine and Heart Diseases
| Article | Year |
|---|---|
Sleeping hearts: the role of the heart in sleeping sickness (human African trypanosomiasis).
Topics: Adult; Animals; Eflornithine; Electrocardiography; Female; Heart Diseases; Humans; Male; Melarsoprol | 2007 |
2 other studies available for eflornithine and Heart Diseases
| Article | Year |
|---|---|
Difluoromethylornithine inhibits hypertrophic, pro-fibrotic and pro-apoptotic actions of aldosterone in cardiac cells.
Topics: Aldosterone; Animals; Apoptosis; Biogenic Polyamines; Cells, Cultured; Eflornithine; Fibrosis; Gene | 2010 |
Polyamines mediate uncontrolled calcium entry and cell damage in rat heart in the calcium paradox.
Topics: Animals; Calcium; Cytosol; Eflornithine; Female; Heart Diseases; Hypothermia, Induced; Microscopy, E | 1987 |