eflornithine has been researched along with Granulocytic Leukemia, Chronic in 3 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grzelkowska, K | 2 |
| Motyl, T | 2 |
| Ostrowski, J | 1 |
| Trzeciak, L | 1 |
| Ask, A | 1 |
| Persson, L | 1 |
| Rehnholm, A | 1 |
| Frostesjö, L | 1 |
| Holm, I | 1 |
| Heby, O | 1 |
| Kasterka, M | 1 |
| Blachowski, S | 1 |
| Sysa, P | 1 |
3 other studies available for eflornithine and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
The effect of OA on proliferation and polyamine metabolism of K 562 leukemic cells and their responsiveness to natural killer cell activity.
Topics: Base Sequence; Biogenic Polyamines; Cell Division; Eflornithine; Humans; Killer Cells, Natural; Leuk | 1995 |
Development of resistance to hydroxyurea during treatment of human myelogenous leukemia K562 cells with alpha-difluoromethylornithine as a result of coamplification of genes for ornithine decarboxylase and ribonucleotide reductase R2 subunit.
Topics: Animals; Blotting, Northern; Blotting, Southern; Cricetinae; Cricetulus; DNA Probes; Drug Resistance | 1993 |
TGF-beta 1 inhibits polyamine biosynthesis in K 562 leukemic cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosylmethionine Decarboxylase; Apoptosis; Cell Div | 1993 |